Jonathan Michaels BA (Cantab), MB BChir MA (Cantab), FRCS (Ed), MChir (Cantab)

Jonathan Michaels Large

Honorary Professor of Clinical Decision Science

Health Economics and Decision Science
University of Sheffield
Regent Court, 30 Regent Street
Sheffield S1 4DA

Office: 1011

Tel: (+44) (0)114 222 2993 (Secretary)
Fax: (+44) (0)114 222 0749


I have had close links with the School of Health and Related Research in Sheffield since moving to Sheffield as a Consultant Vascular Surgeon in 1994.  I was appointed to an Honorary Chair at the School of Health and Related Research in 2003 and to a Chair of Professor of Vascular Surgery in 2004.  I stopped my clinical practice in 2011 but have continued as Professor of Clinical Decision Science continuing with a number of research projects related to technology appraisal and decision science.  I am currently leading the NIHR Programme Grant looking at The Design, Development, Commissioning and Evaluation of Patient Focused Vascular Services.

Prior to moving to Sheffield in 1994, I was a Clinical Lecturer at the Nuffield Department of Surgery in Oxford.

Research Interests

My research interests include clinical decision science, economic and decision analytic modelling, technology appraisal and the organisation and delivery of sub-specialist services.  Due to my previous clinical experience many of these projects relate to areas of vascular disease, although I also have wider interests relating to a range of technologies and issues around outcome assessment and decision science in general.

Teaching Interests

In the past I have been closely involved in teaching of both clinical trainees and post graduate students on the masters programmes.  I was involved in the development and running of the masters programme in clincial research and have supervised and examined for higher degrees.

Current Projects

  • Studies of the effectiveness and cost effectiveness of treatments for peripheral arterial disease.
  • Studies of the effectiveness and cost effectiveness of new treatments for varicose veins.
  • Studies relating to clinical decision making in areas of vascular disease including aortic aneurysm and carotid disease.
  • Studies of the drivers to the configuration of sub-specialist vascular services.
  • Studies of patient and societal preferences for various aspects of service provision and delivery. 
  • The development of Patient Reported Outcome Measures (PROMs) for vascular disease.

Professional Activities

  • Chair of Steering Committee for BASIL 2 and BASIL 3 Trials
  • Previous Vice Chair of NICE Appraisal Committee
  • Previous Chair of NICE Guideline Development Group for Peripheral Arterial Disease
  • Previous Chair of Interventional Procedures Priorities Panel and Member of Prioritisation Group and Strategy and Oversight Group for the NIHR HTA Programme
  • Recently a Member of Editorial Board British Journal of Surgery

Key Publications

  • Phillips, P., Lumley, E., Duncan, R., Aber, A., Woods, H.B., Jone, G.L., Michaels, J. (2018) 'A systematic review of qualitative research into people's experiences of living with venous leg ulcers', Journal of Advanced Nursing, 74:(3):550-63.
  • Aber, A., Lumley, E., Phillips, P., Woods, H.B., Jones, G., Michaels, J. (2018) 'Themes that Determine Quality of Life in Patients with Peripheral Arterial Disease: A Systematic Review', Patient.
  • Sidloff, D.A., Saratzis, A., Sweeting, M.J., Michaels, J., Powell, J.T., Thompson, S.G., et al. (2017). Sex differences in mortality after abdominal aortic aneurysm repair in the UK, British Journal of Surgery, 104(12):1656-64.
  • Phillips, P., Poku,E., Essat, M., Woods, H.B., Goka, E.A., Kaltenthaler, E.C., Walters, S., Shackley, P., Michaels, J. (2017). 'Procedure Volume and the Association with Short-term Mortality Following Abdominal Aortic Aneurysm Repair in European Populations: A Systamtic Review. European Journal of Vascular and Endovascular Surgery, 53(1):77-88.
  • Michaels, J. A. (2016). 'Bridging the gap between academics and practitioners', The BMJ Opinion, [Internet]. 13 March 2018; (23 Feb). Available from: