Dr Emma Simpson

All publications

Journal articles

• Siegfried EC, Simpson EL, Cork MJ, Arkwright PD, Wine Lee L, Chen Z, Prescilla R, Bansal A, Levit NA & Rodríguez Marco A (2023) Dupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years. Dermatology and Therapy, 13(9), 1987-2000.
• Davis S, Simpson E, Hamilton J, James MM-S, Rawdin A, Wong R, Goka E, Gittoes N & Selby P (2020) Denosumab, raloxifene, romosozumab and teriparatide to prevent osteoporotic fragility fractures: a systematic review and economic evaluation. Health Technology Assessment, 24(29). View this article in WRRO
• Simpson E, Martyn-St James M, Hamilton J, Wong R, Gittoes N, Selby P & Davis S (2020) Clinical effectiveness of denosumab, raloxifene, romosozumab, and teriparatide for the prevention of osteoporotic fragility fractures : a systematic review and network meta-analysis. Bone, 130. View this article in WRRO
• Simpson EL, Ren S, Hock ES, Stevens JW, Binard A, Pers Y-M, Archer R, Paisley S, Stevenson MD, Herpin C & Ghabri S (2019) Rheumatoid arthritis treated with 6-months of first-line biologic or biosimilar therapy: an updated systematic review and network meta-analysis.. International Journal of Technology Assessment in Health Care. View this article in WRRO
• Tappenden P, Carroll C, Stevens J, Simpson E, Thokala P, Wong R, Wright J & Auer R (2019) Ibrutinib for Treating Waldenström’s Macroglobulinaemia: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 37(1), 7-18. View this article in WRRO
• Tappenden P, Simpson E, Hamilton J, Pollard D, Clowes M, Kaltenthaler E, Meiklejohn D & Morley N (2018) Ibrutinib for Treating Relapsed or Refractory Mantle Cell Lymphoma: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics. View this article in WRRO
• Bermejo I, Ren S, Simpson E, Clowes M, Scott DL, Young A & Stevenson M (2018) Sarilumab for Previously-Treated Moderate or Severe Rheumatoid Arthritis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 36(12), 1427-1437. View this article in WRRO
• Simpson EL, Hock E, Stevenson M, Wong R, Dracup N, Wailoo A, Conaghan PG, Estrach C, Edwards CJ & Wakefield RJ (2018) What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis. Health Technology Assessment, 22(20). View this article in WRRO
• Ren S, Bermejo I, Simpson E, Wong R, Scott D, Young A & Stevenson M (2018) Baricitinib for Previously Treated Moderate or Severe Rheumatoid Arthritis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics. View this article in WRRO
• Wailoo A, Hock ES, Stevenson M, Martyn-St James M, Rawdin A, Simpson E, Wong R, Dracup N, Scott DL & Young A (2017) The clinical effectiveness and Cost-Effectiveness of Treat-To-Target strategies in rheumatoid arthritis: A systematic review and cost-effectiveness analysis. Health Technology Assessment, 21(71), 1-258. View this article in WRRO
• Stevenson MD, Wailoo AJ, Tosh JC, Hernandez-Alava M, Gibson LA, Stevens JW, Archer RJ, Simpson EL, Hock ES, Young A & Scott DL (2017) The Cost-effectiveness of Sequences of Biological Disease-modifying Antirheumatic Drug Treatment in England for Patients with Rheumatoid Arthritis Who Can Tolerate Methotrexate. Journal of Rheumatology, 44(7), 973-980. View this article in WRRO
• Stevenson M, Archer R, Tosh J, Simpson E, Everson-Hock E, Stevens J, Hernandez-Alava M, Paisley S, Dickinson K, Scott D , Young A et al (2016) Corrigendum: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation. Health Technology Assessment, 20(35), 611-614.
• Thokala P, Simpson E, Tappenden P, Stevens J, Dickinson K, Ryder S & Harrison P (2016) Ledipasvir-Sofosbuvir for Treating Chronic Hepatitis C: A NICE Single Technology Appraisal—An Evidence Review Group Perspective. PharmacoEconomics, 34(8), 741-750. View this article in WRRO
• Squires H, Stevenson M, Simpson E, Harvey R & Stevens J (2016) Trastuzumab Emtansine for Treating HER2-Positive, Unresectable, Locally Advanced or Metastatic Breast Cancer After Treatment with Trastuzumab and a Taxane: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 34(7), 673-680. View this article in WRRO
• Stevenson M, Archer R, Tosh J, Simpson E, Everson-Hock E, Stevens J, Hernandez-Alava M, Paisley S, Dickinson K, Scott D , Young A et al (2016) Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation. Health Technology Assessment, 20(35), 1-610. View this article in WRRO
• Simpson EL, Davis S, Thokala P, Breeze PR, Bryden P & Wong R (2015) Sipuleucel-T for the Treatment of Metastatic Hormone-Relapsed Prostate Cancer: A NICE Single Technology Appraisal; An Evidence Review Group Perspective. PharmacoEconomics, 33(11), 1187-1194. View this article in WRRO
• Holmes M, Davis S & Simpson E (2015) Alteplase for the Treatment of Acute Ischaemic Stroke: A NICE Single Technology Appraisal; an Evidence Review Group Perspective. PharmacoEconomics, 33(3), 225-233. View this article in WRRO
• Meng Y, Squires H, Stevens JW, Simpson E, Harnan S, Thomas S, Michaels J, Stansby G & O'Donnell ME (2014) Cost-Effectiveness of Cilostazol, Naftidrofuryl Oxalate, and Pentoxifylline for the Treatment of Intermittent Claudication in People With Peripheral Arterial Disease. Angiology, 65(3), 190-197.
• Simpson EL, Kearns B, Stevenson MD, Cantrell AJ, Littlewood C & Michaels JA (2014) Enhancements to angioplasty for peripheral arterial occlusive disease: systematic review, cost-effectiveness assessment and expected value of information analysis.. Health Technol Assess, 18(10), 1-252.
• Stevens JW, Simpson E, Harnan S, Squires H, Meng Y, Thomas S, Michaels J & Stansby G (2013) Authors' reply: Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication (Br J Surg2012; 99: 1630-1638). British Journal of Surgery, 100(13), 1838-1839.
• Simpson E, Stevenson M, Scope A, Poku E, Minton J & Evans P (2013) Echocardiography in newly diagnosed atrial fibrillation patients: a systematic review and economic evaluation.. Health Technol Assess, 17(36), 1-vi.
• Simpson EL, Michaels JA, Thomas SM & Cantrell AJ (2013) Systematic review and meta-analysis of additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease.. Br J Surg, 100(9), 1128-1137.
• Rafia R, Simpson E, Stevenson M & Papaioannou D (2013) Trabectedin for the Treatment of Advanced Metastatic Soft Tissue Sarcoma: A NICE Single Technology Appraisal. PharmacoEconomics, 31(6), 471-478.
• Simpson EL, Fitzgerald P, Evans P, Tappenden P, Kalita N, Reckless JPD & Bakhai A (2013) Bivalirudin for the treatment of ST-segment elevation myocardial infarction: a NICE single technology appraisal.. Pharmacoeconomics, 31(4), 269-275.
• Hummel SR, Stevenson MD, Simpson EL & Staffurth J (2012) A Model of the Cost-effectiveness of Intensity-modulated Radiotherapy in Comparison with Three-dimensional Conformal Radiotherapy for the Treatment of Localised Prostate Cancer. Clinical Oncology, 24(10).
• Stevens JW, Simpson E, Harnan S, Squires H, Meng Y, Thomas S, Michaels J & Stansby G (2012) Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication.. Br J Surg, 99(12), 1630-1638.
• Squires H, Simpson E, Meng Y, Harnan S, Stevens J, Wong R, Thomas S, Michaels J & Stansby G (2011) A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease.. Health Technol Assess, 15(40), 1-210.
• Hummel S, Simpson EL, Hemingway P, Stevenson MD & Rees A (2011) Intensity-modulated radiotherapy for the treatment of prostate cancer: A systematic review and economic evaluation. Journal of Urology, 186(2), 534-535.
• Jackson RJ, Cooper KL, Tappenden P, Rees A, Simpson EL, Read RC & Nicholson KG (2011) Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review.. J Infect, 62(1), 14-25.
• Hummel S, Simpson EL, Hemingway P, Stevenson MD & Rees A (2010) Intensity-modulated radiotherapy for the treatment of prostate cancer: a systematic review and economic evaluation.. Health Technol Assess, 14(47), 1-iv.
• Simpson EL, Rafia R, Stevenson MD & Papaioannou D (2010) Trabectedin for the treatment of advanced metastatic soft tissue sarcoma.. Health Technol Assess, 14 Suppl 1, 63-67.
• Stevenson MD, Simpson EL, Rawdin AC & Papaioannou DE (2010) A review of discrete event simulation in National Coordinating Centre for Health Technology Assessment-funded work and a case study exploring the cost-effectiveness of testing for thrombophilia in patients presenting with an initial idiopathic venous thromboembolism.. J. Simulation, 4, 14-23.
• Jassem J, Carroll C, Ward SE, Simpson E & Hind D (2009) The clinical efficacy of cytotoxic agents in locally advanced or metastatic breast cancer patients pretreated with an anthracycline and a taxane: a systematic review.. Eur J Cancer, 45(16), 2749-2758.
• Simpson EL, Duenas A, Holmes MW, Papaioannou D & Chilcott J (2009) Spinal cord stimulation for chronic pain of neuropathic or ischaemic origin: systematic review and economic evaluation.. Health Technol Assess, 13(17), iii-154.
• Tappenden P, Jackson R, Cooper K, Rees A, Simpson E, Read R & Nicholson K (2009) Amantadine, oseltamivir and zanamivir for the prophylaxis of influenza (including a review of existing guidance no. 67): a systematic review and economic evaluation.. Health Technol Assess, 13(11), iii-246.
• Tappenden P, McCabe C, Chilcott J, Simpson E, Nixon R, Madan J, Fisk JD & Brown M (2009) Cost-effectiveness of disease-modifying therapies in the management of multiple sclerosis for the Medicare population.. Value Health, 12(5), 657-665.
• Simpson EL, Stevenson MD, Radwin A & Papaioannou D (2009) Thrombophilia testing in people with venous thromboembolism: Systematic review and cost-effectiveness analysis. Health Technology Assessment, 13, iii-50.
• Sutcliffe P, Hummel S, Simpson E, Young T, Rees A, Wilkinson A, Hamdy F, Clarke N & Staffurth J (2009) Use of classical and novel biomarkers as prognostic risk factors for localised prostate cancer: a systematic review.. Health Technol Assess, 13(5), iii.
• Simpson EL, Stevenson MD, Rawdin A & Papaioannou D (2009) Thrombophilia testing in people with venous thromboembolism: systematic review and cost-effectiveness analysis.. Health Technol Assess, 13(2), iii-91.
• Hind D, Ward S, De Nigris E, Simpson E, Carroll C & Wyld L (2007) Hormonal therapies for early breast cancer: systematic review and economic evaluation.. Health Technol Assess, 11(26), iii-134.
• Ward S, Simpson E, Davis S, Hind D, Rees A & Wilkinson A (2007) Taxanes for the adjuvant treatment of early breast cancer: systematic review and economic evaluation.. Health Technol Assess, 11(40), 1-144.
• Simpson EL, Bryant LD, Ruddy R & Atkin K (2006) Developing partnerships for research: Training workshops for mental health service users, carers and workers. Psychiatric Bulletin, 30(2), 67-69.
• Simpson EL & House AO (2003) User and carer involvement in mental health services: from rhetoric to science. BRIT J PSYCHIAT, 183, 89-91.
• Simpson EL & House AO (2002) Involving users in the delivery and evaluation of mental health services: systematic review.. BMJ, 325(7375), 1265.
• Simpson EL, House AO & Barkham M (2002) A Guide to Involving Users, Ex-users and Carers in Mental Health Service Planning, Delivery or Research: a health technology approach. A Guide to Involving Users, Ex-users and Carers in Mental Health Service Planning, Delivery or Research: A Health Technology Approach.
• Lawrenson RA, Whalley A, Simpson E & Farmer RDT (1999) DoH seems to have underestimated incidence of venous thromboembolism in users of combined oral contraceptives. BMJ, 319(7206), 387-387.
• Simpson EL, Barkham M, Gilbody S & House A () Involving service users as trainers for professionals working in adult statutory mental health services.
• Simpson EL, Barkham M, Gilbody S & House A () Involving service users as researchers for the evaluation of adult statutory mental health services.
• Simpson EL, Rafia R, Stevenson MD & Papaioannou D () Trabectedin for the treatment of advanced metastatic soft tissue sarcoma. Health Technology Assessment, 14(Suppl 1), 63-67.
• Hock ES, Martyn-St James M, Wailoo A, Scott DL, Stevenson M, Rawdin A, Simpson EL, Dracup N & Young A () Treat-to-Target Strategies in Rheumatoid Arthritis: a Systematic Review and Cost-Effectiveness Analysis. SN Comprehensive Clinical Medicine.

Chapters

• Simpson EL, Barkham M, Gilbody S & House A () Involving service users as service providers for adult statutory mental health services John Wiley & Sons, Ltd
• Simpson EL, Barkham M, Gilbody S & House A () Involving service users as trainers for professionals working in adult statutory mental health services John Wiley & Sons, Ltd
• Simpson EL, Barkham M, Gilbody S & House A () Involving service users as researchers for the evaluation of adult statutory mental health services John Wiley & Sons, Ltd

Conference proceedings papers

• Wailoo AJ , Stevenson M , Tosh J , Hernández M , Stevens JW , Archer R , Simpson E , Everson Hock E , Scott D , Young A , Paisley S et al (2014) The Cost-Effectiveness of Biologic DMARDs in Patients With Severe or Mild-To-Severe Rheumatoid Arthritis After Conventional DMARDs. ISPOR 17th Annual European Congress, Vol. Value in Health, Vol. 17, Issue 7, A380. Amsterdam, The Netherlands
• Stevenson M , Wailoo A , Tosh J , Hernandez M , Stevens J , Archer R , Simpson E , Everson-Hock E , Scott D , Young A , Paisley S et al (2014) The cost-effectiveness of biologic DMARDs in patients with severe or mild-to-severe RA after conventional DMARDs. SMDM (Society for Medical Decision Making) conference 15th Biennial European Meeting. Antwerp, Belgium
• Wailoo AJ, Stevenson M, Tosh J, Hernández M, Stevens JW, Archer R, Simpson E, everson HE, Scott D, Young A , Paisley S et al (2014) The Cost-Effectiveness of Biologic Dmards in Patients With Severe or Mild-To-Severe Rheumatoid Arthritis After Conventional Dmards. Value in Health, Vol. 17(7) (pp A380-A380)
• Simpson EL , Michaels JA. , Thomas SM & AJ C (2013) Systematic review and meta-analysis of additional technologies to enhance angioplasty for infra-inguinal peripheral arterial occlusive disease.. HTAi 10th Annual Meeting. Seoul, Korea
• Meng Y, Squires H, Stevens JW, Simpson E, Harnan S, Thomas S, Michaels J, Stansby G & O'Donnell M (2012) PCV30 Cost-Effectiveness of Cilostazol, Naftidrofuryl Oxalate, Pentoxifylline and Inositol Nicotinate for the Treatment of Intermittent Claudication in People with Peripheral Arterial Disease in the Uk. Value in Health, Vol. 15(7) (pp A633-A633)
• Duenas A , Simpson E , Chilcott J & M H (2008) Cost-effectiveness of spinal cord stimulation for chronic pain of neuropathic origin in the UK. IFORS (International Federation of Operational Research Societies Conference). Sandton South Africa
• Jackson R , Tappenden P , Cooper K , Simpson E , Rees A , Read R & K N (2008) The clinical effectiveness of oseltamivir, amantadine and zanamivir for the prophylaxis of influenza: A systematic review. Poster M17.4. HTAi 2008. Montreal Canada
• Stevenson MD, Simpson EL, Rawdin A & Papaioannou D (2007) The cost-effectiveness of thrombophilia testing in patients with idiopathic venous thromboembolism. Abstract 3262. 29th Annual Meeting of The Society for Medical Decision Making (SMDM). Pittsburgh, Pennsylvania, USA
• Meng Y, Squires H, Stevens J, Simpson E, Thomas S, Michaels J, Stansby G & O'Donnell M () Cost-effectiveness of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease in the UK (2012)
• Harnan S, Simpson E, Stevens JW, Squires H, Wong R, Meng Y, Thomas S, Michaels J & Stansby G () A systematic review and meta analysis of the clinical effectiveness of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for symptom management of intermittent claudication (2012)

Reports

• Blackmore C, Beecroft C, Parry G, Booth A, Tantam D, Chambers E, Simpson E, Roberts E & Saxon D (2009) A Systematic Review of the Efficacy and Clinical Effectiveness of Group Analysis and Analytic/Dynamic Group Psychotherapy

Posters

• Ghabri S, Simpson EL, Ren S, Hock E, Archer R, Binard A, Pers Y, Stevens JW, Herpin C & Stevenson M (2018) PMS4 - RHEUMATOID ARTHRITIS TREATED WITH SIX-MONTHS OF FIRST-LINE BIOLOGIC OR BIOSIMILAR THERAPY: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS.
• Poku E , Simpson E , Scope A & P E (2012) Diagnostic accuracy of echocardiography for co-existing pathologies in atrial fibrillation patients: systematic review. HTAi 9th Annual Meeting.
• Simpson E, Stevenson M, Hock E, Wong R, Wakefield RJ, Conaghan PG, Estrach C & Edwards C Ultrasound to Guide Treatment Decisions in Rheumatoid Arthritis.