Dr Maria Price

MSci, PhD

School of Medicine and Population Health

Postdoctoral Research Associate

m.l.price@sheffield.ac.uk
+44 114 215 9214

DU10, D Floor Medical School, The Medical School

Full contact details

Dr Maria Price
School of Medicine and Population Health
DU10, D Floor Medical School
The Medical School
Beech Hill Road
Sheffield
S10 2RX

Profile: I am a postdoctoral researcher in the Department of Clinical Medicine, University of Sheffield, investigating breast cancer metastasis into bone. I completed my PhD at the University of Birmingham in 2025, investigating the impact of G protein-coupled receptor (GPCR) modulation on bone remodelling. I have also carried out international collaborative work at the University of Southern Denmark, Odense.

Qualifications

MSci Biochemistry with Professional Placement - University of Birmingham - September 2017-July 2021
PhD Metabolism and Systems Science - University of Birmingham - September 2021-April 2025

Research interests: My research is focused on the bone metastasis of late stage breast cancer. This involves utilising 2D and 3D cell culture models and in vivo models to investigate the activation of dormant breast cancer tumour cells in bone. The aim of my research is to identify new therapies for the treatment of breast cancer bone metastasis, focusing on preventing the activation of dormant tumour cells.

Publications

Show: Featured publications All publications

Featured publications

Price ML, Wyatt RA, Correia J, Areej Z, Hinds M, Crastin A, Hardy RS, Frost M & Gorvin CM (2025) Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts. Journal of Molecular Endocrinology, 74(4).
Martin CS, Crastin A, Sagmeister MS, Kalirai MS, Turner JD, MacDonald L, Kurowska-Stolarska M, Scheel-Toellner D, Taylor AE, Gilligan LC , Storbeck K et al (2024) Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis. Journal of Autoimmunity, 147, 103263-103263.
Price ML, Ley CD & Gorvin CM (2022) The emerging role of heterodimerisation and interacting proteins in ghrelin receptor function. Journal of Endocrinology, 252(1), R23-R39.
Hansen MS, Madsen K, Price M, Søe K, Omata Y, Zaiss MM, Gorvin CM, Frost M & Rauch A () Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity. Bone Research, 12(1).
Fenton CG, Crastin A, Martin CS, Suresh S, Montagna I, Hussain B, Naylor AJ, Jones SW, Hansen MS, Gorvin CM , Price M et al () 11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation. International Journal of Molecular Sciences, 23(13), 7334-7334.

Price ML, Wyatt RA, Correia J, Areej Z, Hinds M, Crastin A, Hardy RS, Frost M & Gorvin CM (2025) Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts. Journal of Molecular Endocrinology, 74(4).
Martin CS, Crastin A, Sagmeister MS, Kalirai MS, Turner JD, MacDonald L, Kurowska-Stolarska M, Scheel-Toellner D, Taylor AE, Gilligan LC , Storbeck K et al (2024) Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis. Journal of Autoimmunity, 147, 103263-103263.
Price ML, Ley CD & Gorvin CM (2022) The emerging role of heterodimerisation and interacting proteins in ghrelin receptor function. Journal of Endocrinology, 252(1), R23-R39.
Hansen MS, Madsen K, Price M, Søe K, Omata Y, Zaiss MM, Gorvin CM, Frost M & Rauch A () Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity. Bone Research, 12(1).
Fenton CG, Crastin A, Martin CS, Suresh S, Montagna I, Hussain B, Naylor AJ, Jones SW, Hansen MS, Gorvin CM , Price M et al () 11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation. International Journal of Molecular Sciences, 23(13), 7334-7334.

Price ML, Wyatt RA, Crastin A, Jamaluddin A, Hardy RS, Frost M & Gorvin CM (2025) G protein-coupled receptor 35 (GPR35) stimulation reduces osteoclast activity in primary human bone cells, Cold Spring Harbor Laboratory.
Price ML, Wyatt RA, Correia J, Areej Z, Hinds M, Crastin A, Hardy RS, Frost M & Gorvin CM (2024) Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts, Cold Spring Harbor Laboratory.