Dr Paul Collini

MBChB PhD BSc MRCP DTM&H FHEA

School of Medicine and Population Health

Senior Clinical Lecturer in Infectious Diseases

p.collini@sheffield.ac.uk
+44 114 215 9530

L Floor, The Medical School

Full contact details

Dr Paul Collini
School of Medicine and Population Health
L Floor
The Medical School
Beech Hill Road
Sheffield
S10 2RX

Profile

For enquiries please contact - SMPH-West-Operational@sheffield.ac.uk

I joined the University of Sheffield in 2006 as a Lecturer and Honorary SpR in Infectious Diseases (based at the Royal Hallamshire Hospital).

I qualified from Edinburgh University Medical School in 1998 and my general medical training was at St George's Hospital London.

I was involved in the roll out programme for ARV in Africa, setting up and running a clinic in Ghana from 2003-2005 while a clinical lecturer at the Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

I am currently a Senior Clinical Lecturer.

Research interests

My research interest is in the innate immune response to pneumococcal infection in HIV, with a specific focus on the role of the macrophage. My MRC clinical training fellowship title is `The modulation of macrophage apoptosis during S. pneumoniae infection by HIV-1 or antiretroviral agents´.

I also have an ongoing interest in the roll out of antiretroviral treatment (ART) for HIV in resource-poor settings. Specifically, I continue to follow a closed cohort of Ghanaian HIV patients on ART in collaboration with researchers from the KNUST in Ghana and the James Cook University Hospital, Middlesbrough and Newcastle University in the UK.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Weissman D, Alameh M-G, de Silva T, Collini P, Hornsby H, Brown R, LaBranche CC, Edwards RJ, Sutherland L, Santra S , Mansouri K et al (2020) D614G Spike mutation increases SARS CoV-2 susceptibility to neutralization. Cell Host & Microbe. View this article in WRRO
Bewley MA, Budd RC, Ryan E, Cole J, Collini P, Marshall J, Kolsum U, Beech G, Emes RD, Tcherniaeva I , Berbers GAM et al (2018) Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.. American Journal of Respiratory and Critical Care Medicine, 198(6). View this article in WRRO
Collini PJ, Bewley MA, Mohasin M, Marriott HM, Miller RF, Geretti AM, Beloukas A, Papadimitropoulos A, Read RC, Noursadeghi M & Dockrell D (2018) HIV gp120 in the Lungs of Antiretroviral Therapy–treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci. American Journal of Respiratory and Critical Care Medicine, 197(12). View this article in WRRO
Collini PJ, Kuijper E & Dockrell DH (2013) Clostridium difficile infection in patients with HIV/AIDS.. Curr HIV/AIDS Rep, 10(3), 273-282.
Dodd MC, Collini PJ & Dockrell DH (2013) Low concordance with HIV testing guidelines in a retrospective review of intensive care practice.. Thorax, 68(11), 1072-1074.
Collini P, Read R & Dockrell D (2012) HIV-1 alters macrophage apoptosis in response to Streptococcus pneumoniae. HIV MEDICINE, 13, 30-30.
Collini PJ, Bauer M, Kuijper E & Dockrell DH (2012) Clostridium difficile infection in HIV-seropositive individuals and transplant recipients. Journal of Infection, 64(2), 131-147. View this article in WRRO
Collini P, Noursadeghi M, Sabroe I, Miller RF & Dockrell DH (2010) Monocyte and macrophage dysfunction as a cause of HIV-1 induced dysfunction of innate immunity.. Curr Mol Med, 10(8), 727-740. View this article in WRRO
Sarfo FS, Bibby DF, Schwab U, Appiah LT, Clark DA, Collini P, Phillips R, Green I, Dittmar MT & Chadwick DR (2009) Inadvertent non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in dual HIV-1/2 and HIV-2 seropositive West Africans: a retrospective study.. J Antimicrob Chemother, 64(3), 667-669.
Collini P, Premchand N, Lockwood D & Greig J (2009) Successful use of miltefosine and sodium stibogluconate, in combination, for the treatment of an HIV-positive patient with visceral leishmaniasis: a case report and brief review of the literature.. Ann Trop Med Parasitol, 103(5), 455-459.
Partridge DG, Collini P & McKendrick MW (2009) HIV testing: the boundaries. A survey of HIV testing practices and barriers to more widespread testing in a British teaching hospital.. Int J STD AIDS, 20(6), 427-428.
Collini P, Schwab U, Sarfo S, Obeng-Baah J, Norman B, Chadwick D, Bibby D & Bedu-Addo G (2009) Sustained immunological responses to highly active antiretroviral therapy at 36 months in a Ghanaian HIV cohort.. Clin Infect Dis, 48(7), 988-991.
Payne BAI, Nsutebu EF, Hunter ER, Olarinde O, Collini P, Dunbar JAT, Basta MST, Elston JWT, Schmid ML, Thaker H & Chadwick DR (2008) Low prevalence of transmitted antiretroviral drug resistance in a large UK HIV-1 cohort. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 62(3), 464-468.
Collini P, Beadsworth M, Anson J, Neal T, Burnham P, Deegan P, Beeching N & Miller A (2007) Community-acquired pneumonia: doctors do not follow national guidelines.. Postgrad Med J, 83(982), 552-555.
Li C, Collini P, Danso K, Owusu-Ofori S, Dompreh A, Candotti D, Opare-Sem O & Allain J-P (2006) GB virus C and HIV-1 RNA load in single virus and co-infected West African individuals.. AIDS, 20(3), 379-386.

All publications

Journal articles

Sharrack S, Cox M, Carter S, Cohen D, Collini P, Dunkley L, Umair H, Jade J, Maxwell JR, Raza M , Nadin T et al (2025) P002 Refining pre-immunosuppression protocols: a national survey and regional quality improvement project focusing on latent tuberculosis infection. Rheumatology, 64(Supplement_3).
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N , Abdelaziz A et al (2025) Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. eClinicalMedicine, 81, 103080-103080.
Callaby H, Olver J, Emery K, Richards KS, Killip M, Groves N, Beadsworth MBJ, Price DA, Cooke GS, Collini P , Cole J et al (2025) Monkeypox virus isolation from longitudinal samples in 11 hospitalised patients. The Lancet Infectious Diseases, 25(1), e4-e5.
Colton H, Barratt N, Temperton N, Hornsby H, Angyal A, Grouneva I, Lindsey BB, Kearns P, Barnes E, Goodyear CS , Richter A et al (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology. View this article in WRRO
Cooper R, Greig J, Piercy H & Collini P (2024) Investigating the Pregnancy and Post-Partum Health Experiences of Women Living with HIV. Maternal and Child Health Journal, 1-8.
Dockrell DH, Breen R, Collini P, Lipman MCI & Miller RF (2024) British HIV Association guidelines on the management of opportunistic infection in people living with HIV: The clinical management of pulmonary opportunistic infections 2024. HIV Medicine, 25(S2), 3-37.
Faust SN, Haynes R, Jones CE, Staplin N, Whittaker E, Jaki T, Juszczak E, Spata E, Wan M, Bamford A , Dimitri P et al (2024) Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Child & Adolescent Health, 8(3), 190-200. View this article in WRRO
Sidhu JK, Siggins MK, Liew F, Russell CD, Uruchurtu ASS, Davis C, Turtle L, Moore SC, Hardwick HE, Oosthuyzen W , Thomson EC et al (2024) Delayed Mucosal Antiviral Responses Despite Robust Peripheral Inflammation in Fatal COVID-19. The Journal of Infectious Diseases, 230(1), e17-e29.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K , Wood GK et al (2023) Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses. Nature Communications, 14(1). View this article in WRRO
Shahi F, Collini P & Darton T (2023) 53 TRANSLATE TB: Transcriptional signatures for latent TB, Sheffield, UK. Clinical Infection in Practice, 20(Supplement 1). View this article in WRRO
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N , Abdelaziz A et al (2023) Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet Diabetes & Endocrinology. View this article in WRRO
Williams DM, Hornsby HR, Shehata OM, Brown R, Gallis M, Meardon N, Newman TAH, Plowright M, Zafred D, Shun-Shion ASM , Hodder AJ et al (2023) Establishing SARS-CoV-2 membrane protein-specific antibodies as a valuable serological target via high-content microscopy. iScience, 26(7). View this article in WRRO
Goldswain H, Dong X, Penrice-Randal R, Alruwaili M, Shawli GT, Prince T, Williamson MK, Raghwani J, Randle N, Jones B , Donovan-Banfield I et al (2023) The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection. Genome Biology, 24(1). View this article in WRRO
Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Wade P et al (2023) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. Chest.
Tricou V, Eyre S, Ramjee M, Collini P, Mojares Z, Loeliger E, Mandaric S, Rauscher M, Brose M, Lefevre I , Folschweiller N et al (2023) A randomized phase 3 trial of the immunogenicity and safety of coadministration of a live-attenuated tetravalent dengue vaccine (TAK-003) and an inactivated hepatitis a (HAV) virus vaccine in a dengue non-endemic country. Vaccine.
Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C , Moore SC et al (2023) SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination. eBioMedicine, 87.
Shakoor S, Durojaiye OC & Collini PJ (2023) Outcomes of outpatient parenteral antimicrobial therapy (OPAT) for urinary tract infections – A single center retrospective cohort study. Clinical Infection in Practice, 17.
Collini P & Mawson RL (2023) A new era of HIV care for age-associated multimorbidity. Current Opinion in Infectious Diseases, 36(1), 9-14.
Siggins MK, Davies K, Fellows R, Thwaites RS, Baillie JK, Semple MG, Openshaw PJM, Zelek WM, Harris CL & Morgan BP (2023) Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19. Immunology, 168(3), 473-492.
Collini P & Winslow DL (2022) Addressing the burden of HIV-associated chronic lung disease in West Africa. AIDS, 36(14), 2075-2076.
Vink E, Davis C, MacLean A, Pascall D, McDonald SE, Gunson R, Hardwick HE, Oosthuyzen W, Openshaw PJM, Baillie JK , Semple MG et al (2022) Viral Coinfections in Hospitalized Coronavirus Disease 2019 Patients Recruited to the International Severe Acute Respiratory and Emerging Infections Consortium WHO Clinical Characterisation Protocol UK Study. Open Forum Infectious Diseases, 9(11).
Keir HR, Long MB, Abo-Leyah H, Giam YH, Vadiveloo T, Pembridge T, Hull RC, Delgado L, Band M, McLaren-Neil F , Adamson S et al (2022) Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial. The Lancet Respiratory Medicine.
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H, Abbott A, Abbott A , Abdallah N et al (2022) Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. The Lancet, 400(10349), 359-368.
Relph KA, Russell CD, Fairfield CJ, Turtle L, de Silva TI, Siggins MK, Drake TM, Thwaites RS, Abrams S, Moore SC , Hardwick HE et al (2022) Procalcitonin is not a reliable biomarker of bacterial coinfection in people with coronavirus disease 2019 undergoing microbiological investigation at the time of hospital admission. Open Forum Infectious Diseases, 9(5). View this article in WRRO
Millar JE, Neyton L, Seth S, Dunning J, Merson L, Murthy S, Russell CD, Keating S, Swets M, Sudre CH , Spector TD et al (2022) Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study. Scientific Reports, 12. View this article in WRRO
Närhi F, Moonesinghe SR, Shenkin SD, Drake TM, Mulholland RH, Donegan C, Dunning J, Fairfield CJ, Girvan M, Hardwick HE , Ho A et al (2022) Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study. The Lancet Digital Health, 4(4), e220-e234.
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N, Abdelaziz A, Abdelfattah M , Abdelqader B et al (2022) Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399(10325), 665-676. View this article in WRRO
RECOVERY Collaborative Group T (2022) Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399(10320), 143-151. View this article in WRRO
Dejnirattisai W, Huo J, Zhou D, Zahradník J, Supasa P, Liu C, Duyvesteyn HME, Ginn HM, Mentzer AJ, Tuekprakhon A , Nutalai R et al (2022) SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses. Cell, 185(3), 467-484.e15. View this article in WRRO
Laundy N, Colley S, Fawcett J, Ryder L, Vedio A, Cohen D & Collini P (2022) Assessment of latent tuberculosis infection pre-immunomodulatory therapy; 5 year experience in a UK centre. Clinical Infection in Practice, 13, 100136-100136.
Kraef C, Bentzon A, Panteleev A, Skrahina A, Bolokadze N, Tetradov S, Podlasin R, Karpov I, Borodulina E, Denisova E , Azina I et al (2021) Delayed diagnosis of tuberculosis in persons living with HIV in Eastern Europe: associated factors and effect on mortality—a multicentre prospective cohort study. BMC Infectious Diseases, 21(1).
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I , Cameron-Ruiz N et al (2021) A prenylated dsRNA sensor protects against severe COVID-19. Science, 374(6567). View this article in WRRO
Colton H, Hodgson D, Hornsby H, Brown R, Mckenzie J, Bradley KL, James C, Lindsey BB, Birch S, Marsh L , Wood S et al (2021) Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust. Wellcome Open Research, 6.
Drake TM, Riad AM, Fairfield CJ, Egan C, Knight SR, Pius R, Hardwick HE, Norman L, Shaw CA, McLean KA , Thompson AAR et al (2021) Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study. The Lancet, 398(10296), 223-237. View this article in WRRO
Niemi MEK, Karjalainen J, Liao RG, Neale BM, Daly M, Ganna A, Pathak GA, Andrews SJ, Kanai M, Veerapen K , Fernandez-Cadenas I et al (2021) Mapping the human genetic architecture of COVID-19. Nature, 600(7889), 472-477. View this article in WRRO
Leclerc QJ, Fuller NM, Keogh RH, Diaz-Ordaz K, Sekula R, Semple MG, Baillie JK, Semple MG, Openshaw PJM, Carson G , Alex B et al (2021) Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England. BMC Health Services Research, 21. View this article in WRRO
Russell CD, Fairfield CJ, Drake TM, Turtle L, Seaton RA, Wootton DG, Sigfrid L, Harrison EM, Docherty AB, de Silva TI , Egan C et al (2021) Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study : a multicentre, prospective cohort study. The Lancet Microbe. View this article in WRRO
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N, Abdelaziz A, Abdelfattah M , Abdelqader B et al (2021) Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. The Lancet, 397(10289), 2049-2059. View this article in WRRO
The Lancet Rheumatology (2021) Going viral: misinformation in the time of COVID-19. The Lancet Rheumatology, 3(6), e393-e393.
Docherty AB, Mulholland RH, Lone NI, Cheyne CP, De Angelis D, Diaz-Ordaz K, Donegan C, Drake TM, Dunning J, Funk S , García-Fiñana M et al (2021) Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK. The Lancet Respiratory Medicine, 9(7), 773-785. View this article in WRRO
Drake TM, Fairfield CJ, Pius R, Knight SR, Norman L, Girvan M, Hardwick HE, Docherty AB, Thwaites RS, Openshaw PJM , Baillie JK et al (2021) Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study. The Lancet Rheumatology, 3(7), e498-e506. View this article in WRRO
Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N, Abdelaziz A, Abdelfattah M , Abdelqader B et al (2021) Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397(10285), 1637-1645. View this article in WRRO
Collini P (2021) Lung function declines more rapidly in treated HIV-positive people than in HIV-negative people. The Lancet Healthy Longevity, 2(4), e183-e184.
Thwaites RS, Sanchez Sevilla Uruchurtu A, Siggins MK, Liew F, Russell CD, Moore SC, Fairfield C, Carter E, Abrams S, Short C-E , Thaventhiran T et al (2021) Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19. Science Immunology, 6(57).
Bloom CI, Drake TM, Docherty AB, Lipworth BJ, Johnston SL, Nguyen-Van-Tam JS, Carson G, Dunning J, Harrison EM, Baillie JK , Semple MG et al (2021) Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 : a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK. The Lancet Respiratory Medicine, 9(7), 699-711. View this article in WRRO
Abaleke E, Abbas M, Abbasi S, Abbott A, Abdelaziz A, Abdelbadiee S, Abdelfattah M, Abdul B, Abdul Rasheed A, Abdul-Kadir R , Abdulmumeen A et al (2021) Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397(10274), 605-612. View this article in WRRO
Johnston PI, Wright SW, Orr M, Pearce FA, Stevens JW, Hubbard RB & Collini PJ (2021) Worldwide relative smoking prevalence among people living with and without HIV : a systematic review and meta-analysis. AIDS.
Gupta RK, Harrison EM, Ho A, Docherty AB, Knight SR, van Smeden M, Abubakar I, Lipman M, Quartagno M, Pius R , Buchan I et al (2021) Development and validation of the ISARIC 4C deterioration model for adults hospitalised with COVID-19: a prospective cohort study. The Lancet Respiratory Medicine, 9(4), 349-359. View this article in WRRO
McMaster D, Courtenay M, Santucci C, Davies AP, Kirby A, Seddon O, Price DA, Barlow G, Lim FH, Davies BS , O’Shea MK et al (2020) Consensus-based antimicrobial resistance and stewardship competencies for UK undergraduate medical students. JAC-Antimicrobial Resistance, 2(4). View this article in WRRO
Weissman D, Alameh M-G, de Silva T, Collini P, Hornsby H, Brown R, LaBranche CC, Edwards RJ, Sutherland L, Santra S , Mansouri K et al (2020) D614G Spike mutation increases SARS CoV-2 susceptibility to neutralization. Cell Host & Microbe. View this article in WRRO
Drake TM, Docherty AB, Harrison EM, Quint JK, Adamali H, Agnew S, Babu S, Barber CM, Barratt S, Bendstrup E , Bianchi S et al (2020) Outcome of hospitalization for COVID-19 in patients with interstitial lung disease. An international multicenter study. American Journal of Respiratory and Critical Care Medicine, 202(12), 1656-1665. View this article in WRRO
Ellis PK, Shackley F, Ugonna K, Ryan CE, Hughes D, Owens S, Brown P, Riordan A, Ilozue CI, Rowland-Jones SL & Collini PJ (2020) Chronic lung disease in patients with perinatally acquired HIV in England: a retrospective case-note review. Pediatric Infectious Disease Journal.
Keeley AJ, Parkash V, Tunbridge A, Greig J, Collini P, McKane W & Tattersall RS (2020) Anakinra in the treatment of protracted paradoxical inflammatory reactions in HIV-associated tuberculosis in the United Kingdom : a report of two cases. International Journal of STD & AIDS, 31(8), 808-812.
Keeley AJ, Parkash V, Tunbridge A, Greig J, Collini P & Tattersall RS (2020) P24 The successful use of anakinra to control protracted immune reconstitution inflammatory syndrome in HIV associated tuberculosis: a report of two cases. Rheumatology, 59(Supplement_2).
Bewley MA, Budd RC, Ryan E, Cole J, Collini P, Marshall J, Kolsum U, Beech G, Emes RD, Tcherniaeva I , Berbers GAM et al (2018) Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.. American Journal of Respiratory and Critical Care Medicine, 198(6). View this article in WRRO
Collini PJ, Bewley MA, Mohasin M, Marriott HM, Miller RF, Geretti AM, Beloukas A, Papadimitropoulos A, Read RC, Noursadeghi M & Dockrell D (2018) HIV gp120 in the Lungs of Antiretroviral Therapy–treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci. American Journal of Respiratory and Critical Care Medicine, 197(12). View this article in WRRO
Bewley MA, Preston JA, Mohasin M, Marriott HM, Budd RC, Swales J, Collini P, Greaves DR, Craig RW, Brightling CE , Donnelly LE et al (2017) Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.. American Journal of Respiratory and Critical Care Medicine, 196(7), 845-855. View this article in WRRO
Parkash V, Mudhar HS, Wagner BE, Raoult D, Batty R, Lepidi H, Burke J, Collini P & de Silva T (2017) Bilateral Ocular Myositis Associated with Whipple's Disease. Ocular Oncology and Pathology, 3(1), 17-21. View this article in WRRO
Collini P & Morris A (2016) Maintaining lung health with longstanding HIV. Current Opinion in Infectious Diseases, 29(1), 31-38. View this article in WRRO
Collini PJ, Kuijper E & Dockrell DH (2013) Clostridium difficile infection in patients with HIV/AIDS.. Curr HIV/AIDS Rep, 10(3), 273-282.
Dodd MC, Collini PJ & Dockrell DH (2013) Low concordance with HIV testing guidelines in a retrospective review of intensive care practice.. Thorax, 68(11), 1072-1074.
Dodd M, Collini P, Dockrell D & Scott C (2012) A retrospective study of HIV testing in intensive care: significant numbers meet testing criteria according to national testing guidelines. HIV MEDICINE, 13, 58-59.
Collini P, Read R & Dockrell D (2012) HIV-1 alters macrophage apoptosis in response to Streptococcus pneumoniae. HIV MEDICINE, 13, 30-30.
Collini PJ, Bauer M, Kuijper E & Dockrell DH (2012) Clostridium difficile infection in HIV-seropositive individuals and transplant recipients. Journal of Infection, 64(2), 131-147. View this article in WRRO
Foster R, Collini P, Goepel J & Green S (2011) A pain in the neck. Journal of Infection, 63(6), e90-e91.
Daigneault M, Preston J, Collini P & Dockrell D (2011) Cross-talk between monocytes and T–lymphocytes modifies cell death processes following Streptococcus pneumoniae infection. Journal of Infection, 63(6), 490-490.
Collini P, Noursadeghi M, Sabroe I, Miller RF & Dockrell DH (2010) Monocyte and macrophage dysfunction as a cause of HIV-1 induced dysfunction of innate immunity.. Curr Mol Med, 10(8), 727-740. View this article in WRRO
Collini P, Sarfo S, Bedu-Addo G, Chadwick D & Schwab U (2010) Immunological outcomes after 5 years of HAART in a West African HIV cohort attending a public clinic. HIV MEDICINE, 11, 27-28.
Sarfo FS, Bibby DF, Schwab U, Appiah LT, Clark DA, Collini P, Phillips R, Green I, Dittmar MT & Chadwick DR (2009) Inadvertent non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in dual HIV-1/2 and HIV-2 seropositive West Africans: a retrospective study.. J Antimicrob Chemother, 64(3), 667-669.
Collini P, Premchand N, Lockwood D & Greig J (2009) Successful use of miltefosine and sodium stibogluconate, in combination, for the treatment of an HIV-positive patient with visceral leishmaniasis: a case report and brief review of the literature.. Ann Trop Med Parasitol, 103(5), 455-459.
Partridge DG, Collini P & McKendrick MW (2009) HIV testing: the boundaries. A survey of HIV testing practices and barriers to more widespread testing in a British teaching hospital.. Int J STD AIDS, 20(6), 427-428.
Collini P, Schwab U, Sarfo S, Obeng-Baah J, Norman B, Chadwick D, Bibby D & Bedu-Addo G (2009) Sustained immunological responses to highly active antiretroviral therapy at 36 months in a Ghanaian HIV cohort.. Clin Infect Dis, 48(7), 988-991.
Collini P & Greig J (2009) Recurrent respiratory infection. HIV needs to be excluded.. BMJ, 339, b5135.
Payne BAI, Nsutebu EF, Hunter ER, Olarinde O, Collini P, Dunbar JAT, Basta MST, Elston JWT, Schmid ML, Thaker H & Chadwick DR (2008) Low prevalence of transmitted antiretroviral drug resistance in a large UK HIV-1 cohort. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 62(3), 464-468.
Collini P, Beadsworth M, Anson J, Burnham P, Deegan P, Beeching N & Miller A (2007) Community acquired pneumonia (CAP): are doctors following the guidelines?. Journal of Infection, 55(3), e84-e84.
Collini P, Beadsworth M, Anson J, Neal T, Burnham P, Deegan P, Beeching N & Miller A (2007) Community-acquired pneumonia: doctors do not follow national guidelines.. Postgrad Med J, 83(982), 552-555.
Li C, Collini P, Danso K, Owusu-Ofori S, Dompreh A, Candotti D, Opare-Sem O & Allain J-P (2006) GB virus C and HIV-1 RNA load in single virus and co-infected West African individuals.. AIDS, 20(3), 379-386.
Michael BD, Dunai C, Needham EJ, Tharmaratnam K, Williams R, Huang Y, Boardman SA, Clark JJ, Sharma P, Subramaniam K , Wood GK et al () Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses. Nature Communications, 15(1).
Sandercock P, Darbyshire J, DeMets D, Fowler R, Lalloo D, Munavvar M, Warris A, Wittes J, Cradduck-Bamford A, Barton J , Basoglu A et al () Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Nature Communications, 15(1).
Gupta V, Kariotis S, Rajab MD, Errington N, Alhathli E, Jammeh E, Brook M, Meardon N, Collini P, Cole J , Wild JM et al () Unsupervised machine learning to investigate trajectory patterns of COVID-19 symptoms and physical activity measured via the MyHeart Counts App and smart devices. npj Digital Medicine, 6(1).
Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H, Abbott A, Abbott A , Abdallah N et al () Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet. View this article in WRRO
Colton H, Hodgson D, Hornsby H, Brown R, Mckenzie J, Bradley KL, James C, Lindsey BB, Birch S, Marsh L , Wood S et al () Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust. Wellcome Open Research, 6, 220-220.
Colton H, Hodgson D, Hornsby H, Brown R, Mckenzie J, Bradley KL, James C, Lindsey BB, Birch S, Marsh L , Wood S et al () Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust. Wellcome Open Research, 6, 220-220.
Yates T, Zaccardi F, Islam N, Razieh C, Gillies CL, Lawson CA, Chudasama Y, Rowlands A, Davies MJ, Docherty AB , Openshaw PJM et al () Obesity, ethnicity and risk of critical care, mechanical ventilation and mortality in patients admitted to hospital with COVID‐19: Analysis of the ISARIC CCP‐UK cohort. Obesity.

Chapters

Dockrell DH, Collini PJ & Marriott HM (2013) Alveolar Macrophages, Mucosal Immunology of Acute Bacterial Pneumonia (pp. 1-48). Springer New York

Conference proceedings papers

Saunders L, Collier G, Chan H, Hughes P, Smith L, Watson J, Gabriel Z, Meiring J, Plowright M, Newman T , Eaden J et al (2022) Longitudinal lung function assessment of patients hospitalised with COVID-19 using 1H and 129Xe lung MRI. 14.02 - Imaging
Cooper R, Collini P & Greig J (2022) HIV in postpartum women: Still a turbulent time. Clinical Infection in Practice, Vol. 13(Supplement 1). Virtual, 20 May 2021 - 20 May 2021.
Cooper R, Collini P, Piercy H & Greig J (2022) Investigating the pregnancy and post-partum health experiences of women living with HIV: the NESTOR study. HIV MEDICINE, Vol. 23 (pp 7-8)
Colley S, Laundy N, Vedio A, Cohen DB & Collini PJ (2021) P34 5-year experience of latent tuberculosis Infection (LTBI) management pre-immunomodulatory therapy at a tertiary hospital infectious diseases unit in the UK. Thorax, Vol. 76(Suppl 2) (pp A84-A84). Online, 24 November 2021 - 26 November 2021.
Cooper R, Collini P & Greig J (2021) HIV control in post-partum mothers: still a turbulent time. HIV MEDICINE, Vol. 22 (pp 52-52)
Mair L, Keeley A, Collini P & Piercy H (2020) Managing non-communicable comorbidity in people with HIV: how much is there and who is managing it? A retrospective case-record review in Sheffield. HIV MEDICINE, Vol. 21 (pp 53-54)
Keeley AJ, Parkash V, Tunbridge A, Greig J, Collini P & Tattersall RS (2020) THE SUCCESSFUL USE OF ANAKINRA TO CONTROL PROTRACTED IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME IN HIV ASSOCIATED TUBERCULOSIS: A REPORT OF TWO CASES. RHEUMATOLOGY, Vol. 59
Collini PJ, Mitchell C, Dockrell DH, Hubbard R & Lawson R (2019) P259 A better approach to COPD case finding is required in people with HIV. Thorax, Vol. 74(Suppl 2). London, UK, 4 December 2019 - 6 December 2019. View this article in WRRO
Collini P, Hubbard R, Teare D, Chopra M, Allen D & Berry S (2018) A pilot study to investigate respiratory ill health in people living with HIV. HIV MEDICINE, Vol. 19 (pp S72-S72) View this article in WRRO
Talbot B, Stokes CA, Collini PJ & Condliffe AM (2017) P52 Exploring the interaction between hiv-1 gp120, bronchial airway epithelial cells and macrophages. Cellular insights into lung injury repair
Stewart N, Chan H-F, Hughes P, Collier G, Horn F, Norquay G, Parra-Robles J, Yates D, Collini P, Lawson R , Marshall H et al (2016) Comparison of 3 He and 129 Xe MRI for evaluation of lung microstructure and ventilation at 1.5 T. European Respiratory Journal, Vol. 48(suppl 60), 3 September 2016 - 7 September 2016. View this article in WRRO
Collini PJ & Dockrell DH (2013) Invasive pneumococcal disease among HIV-1 seropositive individuals in the era of highly active antiretroviral therapy: does HIV-1 impair the macrophage host response to pneumococci?. LANCET, Vol. 381 (pp 31-31)
Daigneault M, Collini P, Marriott HM, Preston J, Mitchell T & Dockrell D (2010) Monocytes promote T-lymphocyte apoptosis following Streptococcus pneumoniae challenge. IMMUNOLOGY, Vol. 131 (pp 179-179)
Saunders L, Collier G, Chan H-F, Hughes P, Smith L, Stewart N, Brooke J, Watson J, Meiring J, Gabriel Z , Newman T et al () Impaired xenon gas transfer observed one year after hospitalisation due to COVID-19 in patients with signs of interstitial lung disease.. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
Saunders L, Collier G, Chan H-F, Hughes P, Smith L, Marshall H, Eaden J, Bray J, Capener D, Armstrong L , Rodgers J et al () Multinuclear lung MRI assessment of COVID-19 patients at 6 and 12 weeks after hospital admission. ISMRM Annual Meeting, 7 May 2022 - 12 May 2022.

Presentations

Lim JJ, Roberts C, Jauhar Ali SN, Collini P, Burney A, Hughes D & Lim JJ Exploring students’ and examiners’ perceptions of the sequential OSCE: A qualitative study. Basel, Switzerland.

Preprints

Horby PW, Peto L, Staplin N, Campbell M, Pessoa-Amorim G, Mafham M, Emberson JR, Stewart R, Prudon B, Uriel A , Green CA et al (2022) Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial, Cold Spring Harbor Laboratory.
Saunders LC, Collier GJ, Chan H-F, Hughes PJC, Smith LJ, Watson J, Meiring J, Gabriel Z, Newman T, Plowright M , Eaden JA et al () Longitudinal lung function assessment of patients hospitalised with COVID-19 using ¹H and ¹²⁹Xe lung MRI, Cold Spring Harbor Laboratory.
Horby PW, Emberson JR, Mafham M, Campbell M, Peto L, Pessoa-Amorim G, Spata E, Staplin N, Lowe C, Chadwick DR , Brightling C et al () Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis, Cold Spring Harbor Laboratory.
Williams DM, Hornsby H, Shehata OM, Brown R, Zafred D, Shun-Shion ASM, Hodder AJ, Bliss D, Metcalfe A, Edgar JR , Gordon DE et al () A high content microscopy-based platform for detecting antibodies to the nucleocapsid, spike and membrane proteins of SARS-CoV-2, Cold Spring Harbor Laboratory.
Hodgson D, Colton H, Hornsby H, Brown R, Mckenzie J, Bradley KL, James C, Lindsey BB, Birch S, Marsh L , Wood S et al () Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust.
Weissman D, Alameh M-G, de Silva T, Collini P, Hornsby H, Brown R, LaBranche CC, Edwards RJ, Sutherland L, Santra S , Mansouri K et al () D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization, Cold Spring Harbor Laboratory.

Teaching interests: I am a fellow of the Higher Education Academy and lecture on the MPH and MBChB courses at the University of Sheffield and the DTM&H at the Liverpool School for Tropical Medicine.