Dr Alisdair McNeill


Neuroscience, School of Medicine and Population Health

Senior Clinical Lecturer in Neurogenetics

Consultant in Clinical Genetics at Sheffield Children's Hospital NHS Foundation Trust

Alisdair McNeill portrait photo
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+44 114 222 2267

Full contact details

Dr Alisdair McNeill
Neuroscience, School of Medicine and Population Health
Sheffield Institute for Translational Neuroscience (SITraN)
385a Glossop Road
S10 2HQ

I qualified MBChB (Hons) from Edinburgh University in 2004 and obtained the MRCP (UK) in 2007. I undertook Medical SHO training in Newcastle-upon-Tyne and Edinburgh, Clinical Genetics SpR training in the West Midlands and an MRC Clinical Research Training Fellowship at UCL.

Research interests

My research interest focuses on the genetic cause(s) of neurological disorders, in children and adults. In recent years work in my group has identified novel neurogenetic syndromes associated with variants in the SOX4, SOX11, MYT1L and SLC12A2 genes.  

In adults, my interest centres on studying the early (prodromal) stages of neurodegenerative disease using carriers of genetic mutations.  We have used gait analysis and wearable sensors to identify preclinical motor changes in presymptomatic mutation carriers (22q11 deletion, genetic ataxias).  

I am happy to consider applications from self funded students interested in PhD projects in this field. 

Current projects

  • Gait analysis as a stratification tool in neurological disorders (with Prof Claudia Mazza, INSIGNEO and Prof Bandmann, Neuroscience)
  • Genomic identification of novel neurogenetic disorders
  • Cognitive and behavioural phenotyping of rare neurogenetic disorders (with Dr Megan Freeth, Psychology)

Journal articles


Conference proceedings papers

  • McNeill A, Hughes D, Mehta A & Schapira A (2012) Hyposmia and cognitive impairment in gaucher disease patients and carriers. JOURNAL OF MEDICAL GENETICS, Vol. 49 (pp S63-S63) RIS download Bibtex download
  • Aligianis I, Handley M, Carpanini S, Bern D, Yoshimura S, Nunes-Bastos R, Bond F, Kurian M, Rahman F, Hadzhiev Y , Pasha S et al (2011) Micro and Martsolf Syndromes. JOURNAL OF MEDICAL GENETICS, Vol. 48 (pp S36-S36) RIS download Bibtex download


Research group

Doctoral students

  • Tarub Binshalen (Primary supervisor)
  • Louis Stokes (Primary supervisor)

Funding Sources

  • Rosetrees Trust
  • Bailey-Thomas Charitable Fund
  • Royal College of Physicians of Edinburgh
  • Oakdale Trust
  • Sir Hailey-Stewart Trust