Professor Li Su
School of Medicine and Population Health
Professor of Neuroimaging
+44 114 21 59108
Full contact details
School of Medicine and Population Health
Sheffield Institute for Translational Neuroscience (SITraN)
385a Glossop Road
Sheffield
S10 2HQ
- Profile
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Professor Su was awarded a PhD in Computational Neuroscience from University of Kent in 2009. After several years of postdoctoral research in Institute of Psychiatry at King’s College London, MRC Cognition and Brain Sciences Unit and University of Cambridge, he was awarded a highly competitive Senior Research Fellowship from Alzheimer’s Research UK in 2017.
He leads the Artificial Intelligence & Computational Neuroscience Group, which aims to combine innovative and original computational methods with the state-of-the-art brain imaging techniques such as MEG/EEG, 7T MRI and PET in understanding, detecting and developing treatments and care for neurological and psychiatric conditions.
In 2020, he was appointed Professor of Neuroimaging at the University of Sheffield. He also holds a part-time PI position in Department of Psychiatry at University of Cambridge. His research has been recognised through international awards including an International College of Geriatric Psychoneuropharmacology Junior Investigator Award in 2015.
- Research interests
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- Conduct multimodal and longitudinal EEG, MRI and PET studies to discover clinically relevant biomarkers for neurodegenerative disorders (including Parkinson’s disease, Alzheimer’s disease), motor neuron disorders, stroke and other related conditions. Apply machine learning and other advanced imaging analysis to the imaging, genetic, blood and other clinical data.
- Develop advanced imaging analysis methods for basic and clinical neuroscience.
- Develop and validate AI models using clinical and neuroimaging data. Use the model to predict therapeutic effects of potential drug targets on normalising neural network functions from computer simulations.
- Early detection and prevention of dementia. In particular, apply multimodal imaging and VR to find earliest signals for functional declines and pathological abnormalities. Develop and test pharmaceutical and non-pharmaceutical interventions to slow or reverse disease progression for those with increased risk of developing dementia.
- Publications
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Journal articles
- Advanced 3D segmentation and prognostic prediction of high-grade glioma via multimodal MRI, pathological imaging, and Point Cloud data integration. Information Fusion, 126, 103658-103658.
- Baseline impaired insight predicts longitudinal brain atrophy in Alzheimer's disease and related cognitive states: A 30‐month cohort study from the ADNI dataset. Brain and Behavior, 15(10). View this article in WRRO
- Mapping functional hemodynamic and metabolic responses to dementia: a broadband spectroscopy pilot study.. Journal of Biomedical Optics, 30(S2). View this article in WRRO
- Prediction of MGMT methylation status in glioblastoma patients based on radiomics feature extracted from intratumoral and peritumoral MRI imaging. Scientific Reports, 15(1). View this article in WRRO
- Dietary carnosine supplementation in healthy human volunteers: A safety, tolerability, plasma and brain concentration study. Nutrients, 17(13). View this article in WRRO
- Systematic review: Resting state functional MRI as a biomarker for non-invasive brain stimulation in upper limb recovery post-stroke. Neurological Sciences, 46(9), 4233-4257. View this article in WRRO
- Transcutaneous auricular vagus nerve stimulation for acquired immune deficiency syndrome patients with depressive symptoms: a pilot randomized clinical trial. Brain Stimulation, 18(3), 987-989.
- TRanscutaneous lImb reCovEry Post-Stroke (TRICEPS): study protocol for a randomised, controlled, multiarm, multistage adaptive design trial. BMJ Open, 15(3). View this article in WRRO
- Polygenic risk discriminates Lewy body dementia from Alzheimer's disease. Alzheimer's & Dementia, 21(2). View this article in WRRO
- Cerebral perfusion alterations in healthy young adults due to two genetic risk factors of Alzheimer’s disease: APOE and MAPT. Journal of Cerebral Blood Flow & Metabolism, 45(6), 1048-1058. View this article in WRRO
- Enhancing motor imagery decoding in brain–computer interfaces using Riemann tangent space mapping and cross frequency coupling. Biomedical Signal Processing and Control, 99, 106797-106797.
- Individual Variability in the Structural Connectivity Architecture of the Human Brain. The Journal of Neuroscience, 45(5), e2139232024-e2139232024.
- Optimizing non-invasive vagus nerve stimulation for treatment in stroke. Neural Regeneration Research, 20(12), 3388-3399. View this article in WRRO
- The effects of two Alzheimer's disease related genes APOE and MAPT in healthy young adults: An attentional blink study. Journal of Alzheimer’s Disease, 103(1), 167-179. View this article in WRRO
- Outdoor air pollution as a risk factor for Alzheimer’s disease: A systematic review. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(S2). View this article in WRRO
- Addressing the gaps of the functional neuroimaging in young APOEe4 carriers: a systematic review and graph theoretical analysis of brain connectivity. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 20(S9). View this article in WRRO
- Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations. The Lancet Healthy Longevity, 5(12), 100665-100665.
- Protocol for the next generation brain health survey on attitudes, understanding, and exposure to brain health risk factors in young adults globally. Discover Public Health, 21. View this article in WRRO
- Brain age gap, dementia risk factors and cognition in middle age. Brain Communications, 6(6). View this article in WRRO
- Attention network dysfunctions in Lewy body dementia and Alzheimer’s disease. Journal of Clinical Medicine, 13(22). View this article in WRRO
- The effect of outdoor air pollution on Alzheimer’s disease: a systematic review. European Journal of Public Health, 34(Supplement_3).
- The effects of APOEe4 allele on cerebral structure, function, and related interactions with cognition in young adults. Ageing Research Reviews, 101, 102510-102510.
- Differences in grey matter concentrations and functional connectivity between young carriers and non-carriers of the APOE ε4 genotype. Journal of Clinical Medicine, 13(17). View this article in WRRO
- Neuroimaging and clinical findings in healthy middle-aged adults with mild traumatic brain injury in the PREVENT dementia study. JAMA Network Open, 7(8). View this article in WRRO
- Texture‐based morphometry in relation to apolipoprotein ε4 genotype, ageing and sex in a midlife population. Human Brain Mapping, 45(11). View this article in WRRO
- The PREVENT dementia programme: baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia. Brain Communications, 6(3). View this article in WRRO
- Right thalamic volume mediates impact of the dopamine beta-hydroxylase gene on the endowment effect. Behavioural Brain Research, 469, 115050-115050.
- Magnetoencephalography-derived oscillatory microstate patterns across lifespan: the Cambridge centre for ageing and neuroscience cohort. Brain Communications, 6(3). View this article in WRRO
- Investigating the brain’s neurochemical profile at midlife in relation to dementia risk factors. Brain Communications, 6(3). View this article in WRRO
- Entorhinal‐based path integration selectively predicts midlife risk of Alzheimer's disease. Alzheimer's & Dementia, 20(4), 2779-2793. View this article in WRRO
- APOE ɛ4 exacerbates age-dependent deficits in cortical microstructure. Brain Communications, 6(1). View this article in WRRO
- CAIDE DEMENTIA RISK SCORE RELATES TO SEVERITY AND PROGRESSION OF CEREBRAL SMALL VESSEL DISEASE IN HEALTHY MIDLIFE ADULTS: THE PREVENT-DEMENTIA. Cerebral Circulation - Cognition and Behavior, 6, 100050-100050.
- Gene-dose effects of APOE ε4 on age-dependent increases in Peak Width of Skeletonised Mean Diffusivity during midlife. Cerebral Circulation - Cognition and Behavior, 6, 100293-100293.
- A systematic literature review of fMRI and EEG resting-state functional connectivity in Dementia with Lewy Bodies: underlying mechanisms, clinical manifestation, and methodological considerations. Ageing Research Reviews, 93. View this article in WRRO
- Multi‐modal MR and synaptic PET changes in dementia with Lewy bodies. Alzheimer's & Dementia, 19(S17).
- Apoe ε4 exacerbates age‐dependent decline of cortical microstructural changes in cognitively normal midlife individuals: the PREVENT‐Dementia and ALFA studies. Alzheimer's & Dementia, 19(S16).
- Investigating the impact of APOE4 genotype on the association between cerebral blood flow and haematological properties in mid‐life adults. Alzheimer's & Dementia, 19(S16).
- Brain age gap, dementia risk factors and cognition in middle age. Alzheimer's & Dementia, 19(S23).
- Cerebral microbleeds in traumatic brain injury associated with differential risk factors and clinical outcomes: the PREVENT‐Dementia study. Alzheimer's & Dementia, 19(S16).
- Inflammation blood profiles across neurodegenerative diseases. Alzheimer's & Dementia, 19(S17).
- DNA methylation alterations in Lewy Body Dementia. Alzheimer's & Dementia, 19(S12).
- Underlying mechanisms, clinical manifestation, and methodological considerations of functional connectivity in Dementia with Lewy Bodies. Alzheimer's & Dementia, 19(S16).
- Investigating the impact of APOE4 genotype on the association between cerebral blood flow and haematological properties in mid‐life adults. Alzheimer's & Dementia, 19(S10).
- Apoe ε4 exacerbates age‐dependent decline of cortical microstructural changes in cognitively normal midlife individuals: the PREVENT‐Dementia and ALFA studies. Alzheimer's & Dementia, 19(S10).
- Cerebral microbleeds in traumatic brain injury associated with differential risk factors and clinical outcomes: the PREVENT‐Dementia study. Alzheimer's & Dementia, 19(S10).
- Multimodal assessment of mitochondrial function in Parkinson's disease. Brain, 147(1), 267-280. View this article in WRRO
- Genetic risks of Alzheimer’s by APOE and MAPT on cortical morphology in young healthy adults. Brain Communications, 5(5). View this article in WRRO
- tVNS in stroke: a narrative review on the current state and the future. Stroke, 54(10), 2676-2687. View this article in WRRO
- Genetic risk factors of Alzheimer’s Disease disrupt resting-state functional connectivity in cognitively intact young individuals. Journal of Neurology, 270, 4949-4958. View this article in WRRO
- A promising tool to explore functional impairment in neurodegeneration: A systematic review of near-infrared spectroscopy in dementia.. Ageing Research Reviews, 90, 101992-101992.
- A double‐blind, randomized, placebo‐controlled trial of ursodeoxycholic acid (UDCA) in Parkinson's disease. Movement Disorders, 38(8), 1493-1502. View this article in WRRO
- Differential association of cerebral blood flow and anisocytosis in APOE ε4 carriers at midlife. Journal of Cerebral Blood Flow & Metabolism, 43(10), 1672-1684. View this article in WRRO
- Assessment of Alzheimer-related pathologies of dementia using machine learning feature selection. Alzheimer's Research & Therapy, 15. View this article in WRRO
- Illuminating neurodegeneration: a future perspective on near-infrared spectroscopy in dementia research. Neurophotonics, 10(02).
- MRS in neurodegenerative dementias, prodromal syndromes and at-risk states: A systematic review of the literature. NMR in Biomedicine, 36(7). View this article in WRRO
- On the similarities of representations in artificial and brain neural networks for speech recognition. Frontiers in Computational Neuroscience, 16.
- Multifactor mid‐life risk for Alzheimer’s disease associated with alterations in navigation but not episodic memory: the PREVENT‐Dementia study. Alzheimer's & Dementia, 18(S7).
- Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia study. Alzheimer’s Research & Therapy, 14(1).
- Spatial distribution and hierarchical clustering of β-amyloid and glucose metabolism in Alzheimer’s disease. Frontiers in Aging Neuroscience, 14. View this article in WRRO
- Fractal dimension of the brain in neurodegenerative disease and dementia: A systematic review. Ageing Research Reviews, 79, 101651-101651.
- Computational psychiatry and computational neurology : seeking for mechanistic modeling in cognitive impairment and dementia. Frontiers in Computational Neuroscience, 16.
- Fluid-attenuated inversion recovery magnetic resonance imaging textural features as sensitive markers of white matter damage in midlife adults. Brain Communications, 4(3).
- Macrostructural brain alterations at midlife are connected to cardiovascular and not inherited risk of future dementia : the PREVENT-Dementia study. Journal of Neurology, 269, 4299-4309.
- Functional and structural brain network correlates of visual hallucinations in Lewy body dementia. Brain, 145(6), 2190-2205. View this article in WRRO
- Difference in amyloid load between single memory domain and multidomain subjective cognitive decline: a study from the SILCODE. Journal of Alzheimer's Disease, 85(4), 1573-1582.
- CAIDE dementia risk score relates to severity and progression of cerebral small vessel disease in healthy midlife adults : the PREVENT-Dementia study. Journal of Neurology, Neurosurgery & Psychiatry, 93(5), 481-490. View this article in WRRO
- Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy. Journal of Neurology, Neurosurgery & Psychiatry, 93(6), 651-658.
- Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions. Autonomic Neuroscience, 237. View this article in WRRO
- Neuroinflammation in medial temporal regions predicts cognitive decline in dementia with Lewy bodies. Alzheimer's & Dementia, 17(S4).
- The effects of age and hypertension on cerebral small‐vessel disease differ between men and women at midlife: The PREVENT Dementia study. Alzheimer's & Dementia, 17(S10).
- Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study. Journal of Cerebral Blood Flow & Metabolism, 41(11), 2844-2855.
- Resting-state brain connectivity in healthy young and middle-aged adults at risk of progressive Alzheimer’s disease. Neuroscience & Biobehavioral Reviews, 129, 142-153.
- A Genetic Determinant of the Preference Reversal Phenomenon. The American Journal of Psychology, 134(2), 167-174.
- Relationship between tau, neuroinflammation and atrophy in Alzheimer's disease: The NIMROD study. Information Fusion, 67, 116-124.
- Proximity to dementia onset and multi-modal neuroimaging changes: The prevent-dementia study. NeuroImage, 229, 117749-117749.
- Higher midlife CAIDE score is associated with increased brain atrophy in a cohort of cognitively healthy middle-aged individuals. Journal of Neurology, 268(5), 1962-1971.
- The revised Addenbrooke's Cognitive Examination can facilitate differentiation of dementia with Lewy bodies from Alzheimer's disease. International Journal of Geriatric Psychiatry, 36(6), 831-838.
- Imaging tau burden in dementia with Lewy bodies using [18F]-AV1451 positron emission tomography. Neurobiology of Aging, 101, 172-180.
- Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study. Neurobiology of Aging, 98, 124-133.
- Trauma and depressive symptomatology in middle-aged persons at high risk of dementia: the PREVENT Dementia Study. Journal of Neurology, Neurosurgery & Psychiatry, 92(1), 16-21.
- In vivo neuroinflammation and cerebral small vessel disease in mild cognitive impairment and Alzheimer’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 92(1), 45-52.
- Multifaceted pattern of longitudinal imaging changes in cognitively normal midlife adults: The PREVENT‐Dementia study. Alzheimer's & Dementia, 16(S5).
- Progression of cerebral small vessel disease in healthy middle‐aged adults associated with inherited risk of Alzheimer’s disease: The PREVENT‐Dementia study. Alzheimer's & Dementia, 16(S4).
- The prognostic role of microglia and tau PET in Alzheimer’s disease. Alzheimer's & Dementia, 16(S4).
- Impact of mild head injury on diffusion MRI brain characteristics in midlife: Data from the PREVENT Dementia Study. Alzheimer's & Dementia, 16(S5).
- Increased electromagnetic variability in Lewy body dementia: A MILOS study. Alzheimer's & Dementia, 16(S4).
- Multi‐faceted brain changes associated with proximity to dementia onset: The PREVENT‐Dementia study. Alzheimer's & Dementia, 16(S4).
- Hippocampal subfield volumetry in subjects at high risk of dementia: The PREVENT‐Dementia study. Alzheimer's & Dementia, 16(S4).
- Mesoscopic compensations for microscopic impairments in mid‐age individuals with family history of dementia. Alzheimer's & Dementia, 16(S5).
- Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer’s disease. Molecular Neurodegeneration, 15(1).
- Regional hyperperfusion in cognitively normalAPOE ε4allele carriers in mid-life: analysis of ASL pilot data from the PREVENT-Dementia cohort. Journal of Neurology, Neurosurgery & Psychiatry, 91(8), 861-866.
- Midlife alcohol consumption and longitudinal brain atrophy: the PREVENT-Dementia study. Journal of Neurology, 267(11), 3282-3286.
- Semantic and attentional networks in bilingual processing: fMRI connectivity signatures of translation directionality. Brain and Cognition, 143, 105584-105584.
- Hippocampal Subfield Volumes in Middle-Aged Adults at Risk of Dementia. Journal of Alzheimer’s Disease, 75(4), 1211-1218.
- Microglial activation and tau burden predict cognitive decline in Alzheimer's disease.. Brain, 143(5), 1588-1602.
- Can genes modulate anchoring effect?. International Journal of Psychology, 55(6), 1011-1015.
- Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. Neurobiology of Aging, 91, 36-44.
- Correlation of microglial activation with white matter changes in dementia with Lewy bodies. NeuroImage: Clinical, 25, 102200-102200.
- Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning. Information Fusion, 58, 153-167.
- The Stroop effect: An activation likelihood estimation meta-analysis in healthy young adults. Neuroscience Letters, 716, 134683-134683.
- Association between midlife dementia risk factors and longitudinal brain atrophy: the PREVENT-Dementia study. Journal of Neurology, Neurosurgery & Psychiatry, 91(2), 158-161.
- Asymmetrical atrophy of thalamic subnuclei in Alzheimer's disease and amyloid‐positive mild cognitive impairment is associated with key clinical features. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11(1), 690-699.
- The role of information sentiment in popularity on social media: a psychoinformatic and electroencephalogram study. Social Influence, 14(3-4), 133-146.
- Automated Brain MRI Volumetry Differentiates Early Stages of Alzheimer’s Disease From Normal Aging. Journal of Geriatric Psychiatry and Neurology, 32(6), 354-364.
- Sino Longitudinal Study on Cognitive Decline (SILCODE): protocol for a Chinese longitudinal observational study to develop risk prediction models of conversion to mild cognitive impairment in individuals with subjective cognitive decline. BMJ Open, 9(7), e028188-e028188.
- Neuroinflammation and Functional Connectivity in Alzheimer's Disease: Interactive Influences on Cognitive Performance. The Journal of Neuroscience, 39(36), 7218-7226.
- P2‐373: ASYMMETRICAL THALAMIC SUBNUCLEI IN ALZHEIMER'S DISEASE ASSOCIATED WITH GREATER DISEASE SEVERITY. Alzheimer's & Dementia, 15(7S_Part_14).
- The endowment effect in the genes: An exploratory study. Judgment and Decision Making, 14(3), 293-298.
- Normative pathways in the functional connectome. NeuroImage, 184, 317-334.
- Early microglial activation and peripheral inflammation in dementia with Lewy bodies. Brain, 141(12), 3415-3427.
- In vivo coupling of tau pathology and cortical thinning in Alzheimer's disease.. Alzheimers Dement (Amst), 10, 678-687.
- Allocentric and Egocentric Spatial Processing in Middle-Aged Adults at High Risk of Late-Onset Alzheimer’s Disease: The PREVENT Dementia Study. Journal of Alzheimer's Disease, 65(3), 885-896.
- P3‐362: HYPERFUNCTIONAL CONNECTIVITY ASSOCIATED WITH GENETIC RISKS OF DEMENTIA. Alzheimer's & Dementia, 14(7S_Part_23).
- IC‐P‐169: HYPERFUNCTIONAL CONNECTIVITY ASSOCIATED WITH GENETIC RISKS OF DEMENTIA. Alzheimer's & Dementia, 14(7S_Part_2).
- [
11
C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy. Neurology, 90(22).
- Longitudinal diffusion tensor imaging changes in early Parkinson’s disease: ICICLE-PD study. Journal of Neurology, 265(7), 1528-1539.
- Cerebral small vessel disease in middle age and genetic predisposition to late‐onset Alzheimer's disease. Alzheimer's & Dementia, 14(2), 253-258.
- Hippocampal Stratum Radiatum, Lacunosum, and Moleculare Sparing in Mild Cognitive Impairment. Journal of Alzheimer's Disease, 61(1), 415-424.
- [O3–09–04]: INVESTIGATION OF THE RELATIONSHIP BETWEEN TAU AND NEUROINFLAMMATION IN ALZHEIMER's DISEASE USING PET AND REACTION MODELLING. Alzheimer's & Dementia, 13(7S_Part_19).
- The midlife cognitive profiles of adults at high risk of late‐onset Alzheimer's disease: The PREVENT study. Alzheimer's & Dementia, 13(10), 1089-1097.
- Functional neuroimaging findings in healthy middle-aged adults at risk of Alzheimer’s disease. Ageing Research Reviews, 36, 88-104.
- Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease. Neurobiology of Aging, 55, 78-90.
- Multi-modal MRI investigation of volumetric and microstructural changes in the hippocampus and its subfields in mild cognitive impairment, Alzheimer's disease, and dementia with Lewy bodies. International Psychogeriatrics, 29(4), 545-555.
- Neuroimaging of Inflammation in Memory and Related Other Disorders (NIMROD) study protocol: a deep phenotyping cohort study of the role of brain inflammation in dementia, depression and other neurological illnesses. BMJ Open, 7(1), e013187-e013187.
- Structural neuroimaging in preclinical dementia: From microstructural deficits and grey matter atrophy to macroscale connectomic changes. Ageing Research Reviews, 35, 250-264.
- Neuroinflammatory and morphological changes in late-life
depression: the NIMROD study. British Journal of Psychiatry, 209(6), 525-526.
- Differential mesolimbic and prefrontal alterations during reward anticipation and consummation in positive and negative schizotypy. Psychiatry Research: Neuroimaging, 254, 127-136.
- Cortical and Subcortical Changes in Alzheimer's Disease: A Longitudinal and Quantitative MRI Study. Current Alzheimer Research, 13(5), 534-544.
- Differential Atrophy of Hippocampal Subfields: A Comparative Study of Dementia with Lewy Bodies and Alzheimer Disease. The American Journal of Geriatric Psychiatry, 24(2), 136-143.
- Temporal Autocorrelation-Based Beamforming With MEG Neuroimaging Data. Journal of the American Statistical Association, 110(512), 1375-1388.
- Baseline and longitudinal grey matter changes in newly diagnosed Parkinson’s disease: ICICLE-PD study. Brain, 138(10), 2974-2986.
- P3‐003: A longitudinal and quantitative MRI study of Alzheimer's disease. Alzheimer's & Dementia, 11(7S_Part_13).
- P3‐151: Comparing trajectories of grey matter changes in Alzheimer's disease and dementia with lewy bodies: A longitudinal study. Alzheimer's & Dementia, 11(7S_Part_15).
- IC‐P‐075: A longitudinal and quantitative MRI study of Alzheimer's disease. Alzheimer's & Dementia, 11(7S_Part_1).
- Neuroimaging correlates of cognitive impairment and dementia in Parkinson's disease. Parkinsonism & Related Disorders, 21(8), 862-870.
- Longitudinal assessment of global and regional atrophy rates in Alzheimer's disease and dementia with Lewy bodies. NeuroImage: Clinical, 7, 456-462.
- Progressive cortical thinning and subcortical atrophy in dementia with Lewy bodies and Alzheimer's disease. Neurobiology of Aging, 36(4), 1743-1750.
- Grammatical analysis as a distributed neurobiological function. Human Brain Mapping, 36(3), 1190-1201.
- Tissue microstructural changes in dementia with Lewy bodies revealed by quantitative MRI. Journal of Neurology, 262(1), 165-172.
- Analysing neurobiological models using communicating automata. Formal Aspects of Computing, 26(6), 1169-1204.
- Neuroimaging characteristics of dementia with Lewy bodies. Alzheimer's Research & Therapy, 6(2), 18-18.
- Self-regulation of the anterior insula: Reinforcement learning using real-time fMRI neurofeedback. NeuroImage, 88, 113-124.
- Neurobiological Systems for Lexical Representation and Analysis in English. Journal of Cognitive Neuroscience, 25(10), 1678-1691.
- Behavioral and [F-18] fluorodeoxyglucose micro positron emission tomography imaging study in a rat chronic mild stress model of depression. Neuroscience, 169(1), 171-181.
- Process algebraic modelling of attentional capture and human electrophysiology in interactive systems. Formal Aspects of Computing, 21(6).
- Performance of Reactive Interfaces in Stimulus Rich Environments, Applying Formal Methods and Cognitive Frameworks. Electronic Notes in Theoretical Computer Science, 208, 95-111.
- A Tool for the Syntactic Detection of Zeno-timelocks in Timed Automata. Electronic Notes in Theoretical Computer Science, 139(1), 25-47.
- Simulating a Community Mental Health Service During the COVID-19 Pandemic: Effects of Clinician–Clinician Encounters, Clinician–Patient–Family Encounters, Symptom-Triggered Protective Behaviour, and Household Clustering. Frontiers in Psychiatry, 12.
- Resilience to Plasma and Cerebrospinal Fluid Amyloid-β in Cognitively Normal Individuals: Findings From Two Cohort Studies. Frontiers in Aging Neuroscience, 13.
- Predicting the behavioural tendency of loss aversion. Scientific Reports, 9(1).
- Can Your DNA Influence Your Bet-Placing? The Impact of Cannabinoid Receptor 1 Gene on Gambling Tasks. Frontiers in Human Neuroscience, 12.
- Predict Disease Progression With Reaction Rate Equation Modeling of Multimodal MRI and PET. Frontiers in Aging Neuroscience, 10.
- Improving motivation through real-time fMRI-based self-regulation of the nucleus accumbens.. Neuropsychology, 32(6), 764-776.
- Relating dynamic brain states to dynamic machine states: Human and machine solutions to the speech recognition problem. PLOS Computational Biology, 13(9), e1005617-e1005617.
- 18F-AV-1451 positron emission tomography in Alzheimer’s disease and progressive supranuclear palsy. Brain, aww340-aww340.
- Classifying Cognitive Profiles Using Machine Learning with Privileged Information in Mild Cognitive Impairment. Frontiers in Computational Neuroscience, 10.
- Whole-brain patterns of 1H-magnetic resonance spectroscopy imaging in Alzheimer's disease and dementia with Lewy bodies. Translational Psychiatry, 6(8), e877-e877.
- Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex. Scientific Reports, 6(1).
- A Winding Road: Alzheimer’s Disease Increases Circuitous Functional Connectivity Pathways. Frontiers in Computational Neuroscience, 9.
- Temporal perception deficits in schizophrenia: integration is the problem, not deployment of attentions. Scientific Reports, 5(1).
- Mapping tonotopic organization in human temporal cortex: representational similarity analysis in EMEG source space. Frontiers in Neuroscience, 8.
- A Toolbox for Representational Similarity Analysis. PLoS Computational Biology, 10(4), e1003553-e1003553.
- Countering Countermeasures: Detecting Identity Lies by Detecting Conscious Breakthrough. PLoS ONE, 9(3), e90595-e90595.
- Neural correlates of prospective memory in individuals with schizotypal personality features.. Neuropsychology, 28(3), 373-381.
- Subliminal Salience Search Illustrated: EEG Identity and Deception Detection on the Fringe of Awareness. PLoS ONE, 8(1), e54258-e54258.
- Glancing and Then Looking: On the Role of Body, Affect, and Meaning in Cognitive Control. Frontiers in Psychology, 2.
Book chapters
- A Unified Continuous Staging Framework for Alzheimer’s Disease and Lewy Body Dementia via Hierarchical Anatomical Features, Lecture Notes in Computer Science (pp. 13-23). Springer Nature Switzerland
- Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer, Lecture Notes in Computer Science (pp. 184-193). Springer Nature Switzerland
- Dementia, Advances in Magnetic Resonance Technology and Applications (pp. 321-336). Elsevier
- Attentional Deficits in Alzheimer’s Disease: Investigating the Role of Acetylcholine with Computational Modelling, Springer Series in Cognitive and Neural Systems (pp. 113-126). Springer International Publishing
- Salience sensitive control, temporal attention and stimulus-rich reactive interfaces, Human Attention in Digital Environments (pp. 114-144). Cambridge University Press
- On the Fringe of Awareness: The Glance-Look Model of Attention-Emotion Interactions, Lecture Notes in Computer Science (pp. 504-509). Springer Berlin Heidelberg
Conference proceedings
- Attention network dysfunctions in Lewy Body dementia and Alzheimer’s disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). Philadelphia, USA, 28 July 2024 - 28 July 2024. View this article in WRRO
- Addressing the gaps of the functional neuroimaging in young APOEe4 carriers: A systematic review and Graph Theoretical analysis of brain connectivity. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). Philadelphia, USA, 28 July 2024 - 28 July 2024. View this article in WRRO
- From glia to cytokine signatures across the Alzheimer’s spectrum. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S2). United States, 28 July 2024 - 28 July 2024. View this article in WRRO
- Attention network dysfunctions in Lewy body dementia and Alzheimer's disease. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S9). Philadelphia, USA, 28 July 2024 - 28 July 2024. View this article in WRRO
- From glia to cytokine signatures across the Alzheimer's spectrum. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, Vol. 20(S9). Philadelphia, USA, 28 July 2024 - 28 July 2024. View this article in WRRO
- Interrogating visual deficits in dementia using high-density diffuse optical tomography (HD-DOT). Neural Imaging and Sensing 2024 (pp 142-142), 27 January 2024 - 1 February 2024.
- Spatiotemporal Searchlight Representational Similarity Analysis in EMEG Source Space. 2012 Second International Workshop on Pattern Recognition in NeuroImaging (pp 97-100), 2 July 2012 - 4 July 2012.
- Hyperperfusion in middle-aged individuals with genetic risk of sporadic Alzheimer’s disease. ISMRM Annual Meeting, 3 June 2023 - 8 June 2023.
Preprints
- Brain Network Analysis in Alzheimer's Disease and Mild Cognitive Impairment using High-Density Diffuse Optical Tomography, Cold Spring Harbor Laboratory.
- Mapping functional hemodynamic and metabolic responses to dementia: a broadband spectroscopy pilot study, Cold Spring Harbor Laboratory.
- Cognitively healthy young adults withAPOEe4gene show disrupted functional connectivity of graph properties in multiple resting-state networks, Cold Spring Harbor Laboratory.
- Protocol for the Next Generation brain health survey: an international survey of attitudes, understanding and exposure to brain health risk factors in young adults, Research Square Platform LLC.
- Protocol for the Next Generation brain health survey: an international survey of attitudes, understanding and exposure to brain health risk factors in young adults, Center for Open Science.
- The PREVENT Dementia programme: Baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia, Cold Spring Harbor Laboratory.
- Vascular risk factors modulate gender-specific aging of brain white matter structural network, Cold Spring Harbor Laboratory.
- Path integration selectively predicts midlife risk of Alzheimer’s disease, Cold Spring Harbor Laboratory.
- Individual Variability in the Structural Connectivity Architecture of the Human Brain, Cold Spring Harbor Laboratory.
- A systematic review of near-infrared spectroscopy in dementia, Cold Spring Harbor Laboratory.
- On the similarities of representations in artificial and brain neural networks for speech recognition, Cold Spring Harbor Laboratory.
- Assessment of Alzheimer-related Pathologies of Dementia Using Machine Learning Feature Selection, Research Square Platform LLC.
- Assessment of Alzheimer-related Pathologies of Dementia Using Machine Learning Feature Selection, Cold Spring Harbor Laboratory.
- Correlation of Microglial Activation with White Matter Changes in Dementia with Lewy Bodies, Cold Spring Harbor Laboratory.
- Neuroinflammation and functional connectivity in Alzheimer’s disease: interactive influences on cognitive performance, Cold Spring Harbor Laboratory.
- Relating dynamic brain states to dynamic machine states: human and machine solutions to the speech recognition problem, Cold Spring Harbor Laboratory.
- Advanced 3D segmentation and prognostic prediction of high-grade glioma via multimodal MRI, pathological imaging, and Point Cloud data integration. Information Fusion, 126, 103658-103658.
- Grants
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Principal funding sources:
- Alzheimer’s Research UK
- Alzheimer’s Society
- The Lewy Body Society
- Addenbrooke’s Charitable Trust
- Isaac Newton Trust
- UKRI MRC, BBSRC and EPSRC
- NIHR
- Stroke Association