Sue Harnan
Population Health, School of Medicine and Population Health
Senior Research Fellow
+44 114 222 0869
Full contact details
Population Health, School of Medicine and Population Health
1018
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
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I graduated from the University of Sheffield in 1996 with a BSc in Physiology and went on to graduate with an MSc in Science, Culture and Communication at the University of Bath in 2002. I worked in the charitable sector as a systematic reviewer at Penny Brohn Cancer Care for two years before joining ScHARR in 2009.
My primary interest is in Health Technology Assessment, and I have been a member of ScHARR’s Technology Assessment Group (ScHARR-TAG), which conducts assessments for the National Institute for Health and Care Excellence (NICE), since 2009. I have worked on and led systematic reviews and technology appraisals on a wide range of topics as part of this programme of work, and have special interest and expertise in diagnostic and prognostic topics.
I also plan and conduct reviews as part of ScHARR’s Knowledge Exchange partnerships, with industry, public health and charitable funders.
- Research interests
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- Health technology assessment
- Systematic review methodologies including
- Diagnostic reviews
- Rapid reviews
- Review of reviews
- Review techniques for network meta analyses
- Non-RCT reviews
- Systematic review of psychometric properties of outcome measures
- Health and wellbeing benefits of the natural environment
Recent and current projects
Recent and current NICE projects
- Quantitative faecal immunochemical tests to guide referral in primary care for people with a change in bowel habit or abdominal pain [DAP50] (Diagnostic Assessment Report for NICE) (2020- ongoing; project lead)
- Volanesorsen for treating familial chylomicronaemia syndrome [ID1326] (Highly Specialised Technology assessment for NICE) (2018-19; project lead)
- Velmanase alfa for treating alpha-mannosidosis [ID800] (Highly Specialised Technology Assessment for NICE) (2018-19) Trifluridine–tipiracil for treating metastatic gastric or gastro-oesophageal junction cancer after 2 or more therapies [ID1507](Single Technology Appraisal for NICE) (2019)
- Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis (Diagnostic Assessment for NICE) (2017-18; project lead)
Recent and current other work
- The impact of pruritus on health-related quality of life (HRQoL) in patients with end-stage kidney disease (ESKD) or chronic kidney disease associated with pruritus (CKD-aP) on haemodialysis: a systematic review (Commercial sponsor) (2020 – ongoing)
- A series of systematic reviews and meta-analyses of the risk of hip and non-vertebral fractures in patients with chronic kidney disease, Parkinson’s disease and diabetes (Commercial Sponsor) (2019)
- Publications
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Show: Featured publications All publications
Featured publications
Journal articles
- The risk of hip and non-vertebral fractures in patients with Parkinson's disease and parkinsonism : a systematic review and meta-analysis. Bone, 132. View this article in WRRO
- Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis. Health Technology Assessment, 23(30). View this article in WRRO
- Exhaled nitric oxide in the diagnosis of asthma in adults: a systematic review. Clinical and Experimental Allergy, 47(3), 410-429. View this article in WRRO
- Olaparib for Maintenance Treatment of BRCA 1 or 2 Mutated, Relapsed, Platinum-Sensitive Ovarian, Fallopian Tube and Peritoneal Cancer in People Whose Relapsed Disease has Responded to Platinum-Based Chemotherapy: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 35(1), 97-109. View this article in WRRO
- Vedolizumab for Treating Moderately to Severely Active Crohn’s Disease After Prior Therapy: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 34(12), 1241-1253. View this article in WRRO
- Building the Evidence Base of Blood-Based Biomarkers for Early Detection of Cancer: A Rapid Systematic Mapping Review. EBioMedicine. View this article in WRRO
- Association between Transfusion Status and Overall Survival in Patients with Myelodysplastic Syndromes: A Systematic Literature Review and Meta-Analysis. Acta Haematologica, 136(1), 23-42. View this article in WRRO
- Pruning and prioritising: a case study of a pragmatic method for managing a rapid systematic review with limited resources. Evidence & Policy: A Journal of Research, Debate and Practice, 11(4), 589-601. View this article in WRRO
- Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. British Journal of Surgery, 99(12), 1630-1638.
- A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease. Health Technology Assessment, 15(40).
- Magnetic resonance for assessment of axillary lymph node status in early breast cancer: a systematic review and meta-analysis.. Eur J Surg Oncol, 37(11), 928-936. View this article in WRRO
- Clinical decision rules for adults with minor head injury: a systematic review.. J Trauma, 71(1), 245-251.
- Positron emission tomography (PET) for assessment of axillary lymph node status in early breast cancer: A systematic review and meta-analysis.. Eur J Surg Oncol, 37(3), 187-198.
- Clinical decision rules for children with minor head injury: A systematic review. Archives of Disease in Childhood, 96(5), 414-421.
- Measurement of exhaled nitric oxide concentration in asthma: a systematic review and economic evaluation of NIOX MINO, NIOX VERO and Nobreath. Health Technology Assessment, 19(82), 1-330. View this article in WRRO
Conference proceedings papers
- TOWARDS COST-EFFECTIVENESS ANALYSIS OF THE HEALTH AND WELLBEING BENEFITS OF URBAN GREEN SPACE: A MAPPING REVIEW. VALUE IN HEALTH, Vol. 14(7) (pp A343-A343)
All publications
Journal articles
- The risk of hip and non-vertebral fractures in type 1 and type 2 diabetes: A systematic review and meta-analysis update. Bone, 137. View this article in WRRO
- Risks of hip and nonvertebral fractures in patients with CKD G3a-G5D: a systematic review and meta-analysis. American Journal of Kidney Diseases. View this article in WRRO
- The risk of hip and non-vertebral fractures in patients with Parkinson's disease and parkinsonism : a systematic review and meta-analysis. Bone, 132. View this article in WRRO
- Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis. Health Technology Assessment, 23(30). View this article in WRRO
- An Updated Systematic Review of Studies Mapping (or Cross-Walking) Measures of Health-Related Quality of Life to Generic Preference-Based Measures to Generate Utility Values. Applied Health Economics and Health Policy, 17(3), 295-313. View this article in WRRO
- Obinutuzumab with Bendamustine for Treating Follicular Lymphoma Refractory to Rituximab: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 36(10), 1143-1151. View this article in WRRO
- Rapid diagnostic test for antenatal syphilis screening in low-income and middle-income countries: a systematic review and meta-analysis. BMJ Open, 8(2), e018132-e018132. View this article in WRRO
- The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review. BMC Cancer, 17, 697-697. View this article in WRRO
- Mepolizumab for Treating Severe Eosinophilic Asthma: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. Pharmacoeconomics. View this article in WRRO
- Exhaled nitric oxide in the diagnosis of asthma in adults: a systematic review. Clinical and Experimental Allergy, 47(3), 410-429. View this article in WRRO
- Olaparib for Maintenance Treatment of BRCA 1 or 2 Mutated, Relapsed, Platinum-Sensitive Ovarian, Fallopian Tube and Peritoneal Cancer in People Whose Relapsed Disease has Responded to Platinum-Based Chemotherapy: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 35(1), 97-109. View this article in WRRO
- Vedolizumab for Treating Moderately to Severely Active Crohn’s Disease After Prior Therapy: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 34(12), 1241-1253. View this article in WRRO
- Building the Evidence Base of Blood-Based Biomarkers for Early Detection of Cancer: A Rapid Systematic Mapping Review. EBioMedicine. View this article in WRRO
- Association between Transfusion Status and Overall Survival in Patients with Myelodysplastic Syndromes: A Systematic Literature Review and Meta-Analysis. Acta Haematologica, 136(1), 23-42. View this article in WRRO
- A systematic review of fractional exhaled nitric oxide in the routine management of childhood asthma. Pediatric Pulmonology, 51(3), 316-328.
- Fractional exhaled nitric oxide for the management of asthma in adults: a systematic review. European Respiratory Society, 47(3), 751-768. View this article in WRRO
- Acute ischaemic stroke patients – direct admission to a specialist centre or initial treatment in a local hospital? A systematic review. Journal of Health Services Research & Policy, 21(1), 51-60.
- Pruning and prioritising: a case study of a pragmatic method for managing a rapid systematic review with limited resources. Evidence & Policy: A Journal of Research, Debate and Practice, 11(4), 589-601. View this article in WRRO
- Impact of prehospital transfer strategies in major trauma and head injury. Journal of Trauma and Acute Care Surgery, 78(1), 164-177. View this article in WRRO
- Effectiveness and cost-effectiveness of an awareness campaign for colorectal cancer: a mathematical modeling study.. Cancer Causes Control, 25(6), 647-658. View this article in WRRO
- Cost-effectiveness of cilostazol, naftidrofuryl oxalate, and pentoxifylline for the treatment of intermittent claudication in people with peripheral arterial disease.. Angiology, 65(3), 190-197.
- The Cost Effectiveness of Dry Powder Antibiotics for the Treatment of Pseudomonas aeruginosa in Patients with Cystic Fibrosis. PHARMACOECONOMICS, 32(2), 159-172.
- Colistimethate sodium powder and tobramycin powder for inhalation for the treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis: systematic review and economic model.. Health Technol Assess, 17(56), v-181.
- Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis.. Eur Respir Rev, 22(130), 476-486.
- Authors' reply: systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication (Br J Surg 2012; 99: 1630-1638).. Br J Surg, 100(13), 1838-1839.
- Gene expression profiling and expanded immunohistochemistry tests to guide the use of adjuvant chemotherapy in breast cancer management: a systematic review and cost-effectiveness analysis.. Health Technol Assess, 17(44), 1-302. View this article in WRRO
- Systematic review of the efficacy of cilostazol, naftidrofuryl oxalate and pentoxifylline for the treatment of intermittent claudication. British Journal of Surgery, 99(12), 1630-1638.
- Diagnostic accuracy of clinical characteristics for identifying CT abnormality after minor brain injury: a systematic review and meta-analysis.. J Neurotrauma, 29(5), 707-718.
- A systematic review and economic evaluation of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial disease. Health Technology Assessment, 15(40).
- Magnetic resonance for assessment of axillary lymph node status in early breast cancer: a systematic review and meta-analysis.. Eur J Surg Oncol, 37(11), 928-936. View this article in WRRO
- Diagnosis and management of minor head injury in the UK. Journal of Paramedic Practice, 3(8), 418-423.
- Diagnostic management strategies for adults and children with minor head injury: a systematic review and an economic evaluation.. Health Technol Assess, 15(27), 1-202.
- Clinical decision rules for adults with minor head injury: a systematic review.. J Trauma, 71(1), 245-251.
- Positron emission tomography (PET) for assessment of axillary lymph node status in early breast cancer: A systematic review and meta-analysis.. Eur J Surg Oncol, 37(3), 187-198.
- Positron emission tomography (PET) and magnetic resonance imaging (MRI) for the assessment of axillary lymph node metastases in early breast cancer: systematic review and economic evaluation.. Health Technol Assess, 15(4), iii-134.
- Clinical decision rules for children with minor head injury: A systematic review. Archives of Disease in Childhood, 96(5), 414-421.
- Cost-effectiveness of MRI and PET imaging for the evaluation of axillary lymph node metastases in early stage breast cancer.. Eur J Surg Oncol, 37(1), 40-46.
- Measurement of exhaled nitric oxide concentration in asthma: a systematic review and economic evaluation of NIOX MINO, NIOX VERO and Nobreath. Health Technology Assessment, 19(82), 1-330. View this article in WRRO
Conference proceedings papers
- SUN-622 The risk of hip and non-vertebral fractures in diabetes : a systematic review and meta-analysis update. Journal of the Endocrine Society, Vol. 4(Supplement_1). San Francisco, CA, USA, 28 March 2020 - 31 March 2020. View this article in WRRO
- Exhaled Nitric Oxide For The Diagnosis Of Asthma In Adults And Children: A Systematic Review. Value in Health, Vol. 18(7) (pp A345-A345)
- Systematic Review and Meta-Analysis of the Association Between Transfusion Independence (TI) and Overall Survival (OS) in Patients (pts) with Myelodysplastic Syndromes (MDS). Blood, Vol. 124(21) (pp 1934-1934)
- The Cost-Effectiveness of Dry Powder Antibiotics for the Treatment of Pseudomonas Aeruginosa in Patients with Cystic Fibrosis. Value in Health, Vol. 16(7) (pp A372-A372)
- SYSTEMATIC REVIEW OF COLISTIMETHATE SODIUM DRY POWDER AND TOBRAMYCIN DRY POWDER ANTIBIOTICS FOR PSEUDOMONAS AERUGINOSA LUNG INFECTION IN CYSTIC FIBROSIS. VALUE IN HEALTH, Vol. 16(7) (pp A367-A367)
- COST-EFFECTIVENESS OF CILOSTAZOL, NAFTIDROFURYL OXALATE, PENTOXIFYLLINE AND INOSITOL NICOTINATE FOR THE TREATMENT OF INTERMITTENT CLAUDICATION IN PEOPLE WITH PERIPHERAL ARTERIAL DISEASE IN THE UK. VALUE IN HEALTH, Vol. 15(7) (pp A633-A633)
- DIAGNOSTIC ACCURACY OF CLINICAL CHARACTERISTICS FOLLOWING MINOR HEAD INJURY: A SYSTEMATIC REVIEW AND META-ANALYSIS. VALUE IN HEALTH, Vol. 14(7) (pp A245-A245)
- CLINICAL DECISION RULES FOR ADULTS WITH MINOR HEAD INJURY: A SYSTEMATIC REVIEW. VALUE IN HEALTH, Vol. 14(7) (pp A244-A244)
- TOWARDS COST-EFFECTIVENESS ANALYSIS OF THE HEALTH AND WELLBEING BENEFITS OF URBAN GREEN SPACE: A MAPPING REVIEW. VALUE IN HEALTH, Vol. 14(7) (pp A343-A343)
- BIOCHEMICAL MARKERS FOR THE IDENTIFICATION OF INTRACRANIAL INJURY FOLLOWING MINOR HEAD INJURY: A SYSTEMATIC REVIEW AND META-ANALYSIS. VALUE IN HEALTH, Vol. 14(7) (pp A244-A244)
Reports
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Posters
- The risk of hip and non-vertebral fractures in patients with Parkinson's disease and parkinsonism : a systematic review and meta-analysis. Bone, 132. View this article in WRRO
- Teaching interests
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I am a module co-ordinator for HAR6501, Systematic Reviews and Critical Appraisal Techniques on ScHARR’s Masters in Public Health. I also teach on ScHARR’s short courses and bespoke training courses, including our Systematic Review short course, our Rapid Review short course and our short course on Reviewing for Modelling Parameters.