Member Publications
Recent publications from members of the Bateson Centre.

Publications
Journal articles
- Protocol for the YORKSURe prospective multistage study testing the feasibility for early detection of bladder cancer in populations with high disease-specific mortality risk. BMJ Open, 13(9), e076612-e076612.
- insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology. Biology Open, 12(9).
- Blood Pressure in Children with Congenital Adrenal Hyperplasia Due To 21-Hydroxylase Deficiency.. Horm Res Paediatr.
- Biomarkers in congenital adrenal hyperplasia.. Clin Endocrinol (Oxf).
- Neuroscience: Hacking development to understand sensory discrimination. Current Biology, 33(15), R822-R825.
- Diet and Polycystic Kidney Disease: Nutrients, Foods, Dietary Patterns, and Implications for Practice. Seminars in Nephrology, 43(2), 151405-151405.
- The Common PKD1 p.(Ile3167Phe) Variant Is Hypomorphic and Associated with Very Early Onset, Biallelic Polycystic Kidney Disease. Human Mutation, 2023, 1-8.
- Quality of Life in children and young people with Congenital Adrenal Hyperplasia - UK nationwide multicentre assessment.. The Journal of clinical endocrinology and metabolism, dgad405.
- Markers of the ageing macrophage: a systematic review and meta-analysis. Frontiers in Immunology, 14.
- Wearable technology and the cardiovascular system: the future of patient assessment. The Lancet Digital Health, 5(7), e467-e476.
- A PI(3,5)P2 reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomes. Journal of Cell Biology, 222(9).
- Stakeholder-led understanding of the implementation of digital technologies within heart disease diagnosis: a qualitative study protocol. BMJ Open, 13(6), e072952-e072952.
- Formation and closure of macropinocytic cups in Dictyostelium. Current Biology.
- Continuous monitoring of health and mobility indicators in patients with cardiovascular disease: a review of recent technologies. Sensors, 23(12).
- Analysis of the distal urinary tract in larval and adult zebrafish reveals homology to the human system. Disease Models & Mechanisms, dmm.050110.
- Enhancement of iron‐based oxygen carriers through alloying with tungsten oxide for chemical looping applications including water splitting. Greenhouse Gases: Science and Technology.
- The Mechanical Influence of Densification on Initial Epithelial Architecture.
- An arginase 2 promoter transgenic illuminates immune cell polarisation in zebrafish. Disease Models & Mechanisms, 16(6).
- DLL4 promotes partial endothelial-to-mesenchymal transition at atherosclerosis-prone regions of arteries. Vascular Pharmacology, 150, 107178-107178.
- Nutritional Supplementation for the Prevention of Muscle Atrophy in Older People. Nutrition Today, 58(3), 105-118.
- Patient perspectives on ADPKD. Advances in Kidney Disease and Health, 30(3), 294-302.
- Lifestyle Factors in Patients with Bladder Cancer: A Contemporary Picture of Tobacco Smoking, Electronic Cigarette Use, Body Mass Index, and Levels of Physical Activity. European Urology Focus.
- A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo. Aging Cell.
- Layered double hydroxide‐derived copper‐based oxygen carriers for chemical looping applications: oxygen release kinetics and impact of loading on long‐term performance. Greenhouse Gases: Science and Technology.
- Oxidative DNA damage and repair at non-coding regulatory regions. Trends in Cell Biology.
- Abstract 3542: A stem cell model dissects detrimental effects of neuroblastoma-linked chromosomal aberrations on cell differentiation during neural crest development. Cancer Research, 83(7_Supplement), 3542-3542.
- The importance of reaction norms in dietary restriction and ageing research. Ageing Research Reviews, 87, 101926-101926.
- Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia. Disease Models & Mechanisms, 16(4).
- Hypertension in young adults with autosomal dominant polycystic kidney disease: a case for early screening?. Clinical Kidney Journal.
- The association of urinary epidermal growth factors with ADPKD disease severity and progression. Nephrology Dialysis Transplantation.
- WCN23-0391 THE CLINICAL CHARACTERISTICS AND KIDNEY OUTCOME IN CHINESE PATIENTS WITH TYPICAL AND ATYPICAL POLYCYSTIC KIDNEY DISEASE. Kidney International Reports, 8(3), S244-S245.
- Modelling cancer metastasis in Drosophila melanogaster. Cells, 12(5).
- Protocol for the TRANSLATE prospective, multicentre, randomised clinical trial of prostate biopsy technique. BJU International.
- Factors associated with response to growth hormone in pediatric growth disorders: results of a 5-year registry analysis. Journal of the Endocrine Society, 7(5).
- EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy. Arteriosclerosis, Thrombosis, and Vascular Biology, 43(4), 547-561.
- OVERTURE: A worldwide, prospective, observational study of disease characteristics in patients with ADPKD. Kidney International Reports, 8(5), 989-1001.
- Elicitation of health state utilities associated with progression from Bacillus Calmette-Guerin (BCG) unresponsive Non-muscle Invasive Bladder Cancer (NMIBC). PharmacoEconomics - Open.
- Clonal population expansion of Staphylococcus aureus occurs due to escape from a finite number of intraphagocyte niches. Scientific Reports, 13(1), 1-11.
- Accuracy of in vivo microCT imaging in assessing the microstructural properties of the mouse tibia subchondral bone. Frontiers in Endocrinology, 13.
- High glucose increases DNA damage and elevates the expression of multiple DDR genes. Genes, 14(1).
- 3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease. Biomolecules, 13(1).
- Increased fracture risk in Parkinson's disease – An exploration of mechanisms and consequences for fracture prediction with FRAX. Bone, 168, 116651-116651.
- Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis. GeroScience, 45(2), 1263-1270.
- Chronic kidney disease as cardiovascular risk factor in routine clinical practice: a position statement by the Council of the European Renal Association. Nephrology Dialysis Transplantation, 38(3), 527-531.
- Chronic kidney disease as cardiovascular risk factor in routine clinical practice: a position statement by the Council of the European Renal Association. Clinical Kidney Journal, 16(3), 403-407.
- Variants in
ALDH1A2
reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis. Science Translational Medicine, 14(676).
- Venglustat, a novel glucosylceramide synthase inhibitor, in patients at risk of rapidly progressing ADPKD: primary results of a double-blind, placebo-controlled, phase 2/3 randomized clinical trial. American Journal of Kidney Diseases.
- Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation. Frontiers in Cellular Neuroscience, 16.
- Hyperthermic intravesical chemotherapy with mitomycin‐C for the treatment of high‐risk non‐muscle‐invasive bladder cancer patients. BJUI Compass. View this article in WRRO
- Tetraspanin Cd9b plays a role in fertility in zebrafish. PLOS ONE, 17(11). View this article in WRRO
- Unlocking the human inner ear for therapeutic intervention. Scientific Reports, 12, 1-6.
- PMON191 Current Management of Acute Adrenal Insufficiency Related Adverse Events in Children with Congenital Adrenal Hyperplasia- Results of an International Survey of Specialist Centres. Journal of the Endocrine Society, 6(Supplement_1), A621-A621.
- LBMON197 Predictors Of Response To Growth Hormone Treatment In Pediatric Growth Disorders: Analysis From The Answer Program And Nordinet® IOS. Journal of the Endocrine Society, 6(Supplement_1), A592-A592.
- Applying Artificial Intelligence to wearable sensor data to diagnose and predict cardiovascular disease: a review. Sensors, 22(20).
- Genome-wide association study for systemic lupus erythematosus in an egyptian population. Frontiers in Genetics, 13.
- Chronic kidney disease as cardiovascular risk factor in routine clinical practice: a position statement by the Council of the European Renal Association. European Journal of Preventive Cardiology.
- A mechanism for oxidative damage repair at gene regulatory elements. Nature, 609(7929), 1038-1047.
- The mechano-ubiquitinome of articular cartilage: differential ubiquitination and activation of a group of ER-associated DUBs and ER stress regulators. Molecular & Cellular Proteomics.
- Effect of Robot-Assisted Radical Cystectomy vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer—Reply. JAMA, 328(12), 1258-1258.
- Monkeypox and the Urologist: Playing an Important Role in This Emerging Global Outbreak. European Urology.
- Health status of children and young persons with congenital adrenal hyperplasia in the UK (CAH-UK): a cross-sectional multi-centre study. European Journal of Endocrinology, 187(4), 543-553.
- Reply to Bernardo Rocco and Maria Chiara Sighinolfi’s Letter to the Editor re: James W.F. Catto, Pramit Khetrapal, Federico Ricciardi, et al. Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. JAMA 2022;327:2092–103. European Urology.
- 1733MO First results from BladderPath: A randomised trial of MRI versus cystoscopic staging for newly diagnosed bladder cancer. Annals of Oncology, 33, S1330-S1330.
- JAG1-NOTCH4 mechanosensing drives atherosclerosis. Science Advances, 8(35).
- A founder UMOD variant is a common cause of hereditary nephropathy in the British population. Journal of Medical Genetics.
- The STAGED-PKD 2-stage adaptive study with a patient enrichment strategy and treatment effect modeling for improved study design efficiency in patients with ADPKD. Kidney Medicine.
- Presence of chondroitin sulphate and requirement for heparan sulphate biosynthesis in the developing zebrafish inner ear. Frontiers in Cell and Developmental Biology, 10. View this article in WRRO
- Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling. Frontiers in Cardiovascular Medicine, 9. View this article in WRRO
- Nanomedicines targeting the Inflammasome as a promising therapeutic approach for cell senescence. Seminars in Cancer Biology.
- Updates on bladder, kidney and prostate cancers. BJU International, 130(3), 275-276.
- Using 31-phosphorus magnetic resonance spectroscopy (31P-MRS) to identify Parkinson’s Disease subgroups with bioenergetic dysfunction. Journal of Neurology, Neurosurgery & Psychiatry, 93(9), e2.2-e2.2.
- Adrenal Gland Function and Dysfunction During
COVID-19. Hormone and Metabolic Research, 54(08), 532-539.
- Reply to Andreas Skolarikos’s Words of Wisdom re: Effect of Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients with Bladder Cancer: A Randomized Clinical Trial. Eur Urol. In press. European Urology.
- Zebrafish as a model to investigate the CRH axis and interactions with DISC1. Current Opinion in Endocrine and Metabolic Research, 26.
- Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis. The Lancet, 400(10349), 359-368.
- Sexual activity, function and dysfunction after a diagnosis of bladder cancer. The Journal of Sexual Medicine, 19(9), 1431-1441. View this article in WRRO
- A subset of gut leukocytes has telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish. Immunity & Ageing, 19(1).
- Social deprivation and bladder cancer: cause or effect for disparities in survival for affected women. BJU International, 130(3), 301-302.
- P7 Elicitation of Health State Utilities Associated Progression from BCG-Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC) Health States. Value in Health, 25(7), S288-S288.
- Patients with polcystic liver disease have longer waiting times but better clinical outcomes following liver transplantation in the UK. Journal of Hepatology, 77, S814-S814.
- Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. American Journal of Obstetrics and Gynecology, 227(5), 735.e1-735.e25.
- From WEDA to EDTA to ERA: 60 years of supporting European nephrology and counting. Clinical Kidney Journal, 15(8), 1439-1446.
- ChemChaste : simulating spatially inhomogeneous biochemical reaction–diffusion systems for modeling cell–environment feedbacks. GigaScience, 11(2022).
- Abstract 1049: Modulating the polymorphic UGT1A1 gene to enhance camptothecin anti-colorectal effect. Cancer Research, 82(12_Supplement), 1049-1049.
- Research priorities for autosomal dominant polycystic kidney disease : a UK priority setting partnership. BMJ Open, 12(6).
- Race reporting and disparities regarding clinical trials in bladder cancer: a systematic review. Cancer Causes & Control, 33(8), 1071-1081.
- Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model. Cellular Microbiology, 2022, 1-13.
- Editorial: Genomic instability and neurodegeneration. Frontiers in Aging Neuroscience, 14.
- Flank pain has a significant adverse impact on quality of life in ADPKD: the CYSTic-QoL study. Clinical Kidney Journal.
- Towards clinical applications of in vitro-derived axial progenitors. Developmental Biology.
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801)—A randomized phase 3, double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation.. Journal of Clinical Oncology, 40(16_suppl), TPS5103-TPS5103.
- Case of the month from the University of Sheffield,
UK : Expediting definitive treatment in patients with invasive bladder cancer: anMRI ‐guided pathway. BJU International, 129(6), 691-694. - Analytical approaches for the segmentation of the zebrafish brain vasculature. Current Protocols, 2. View this article in WRRO
- Multifaceted control of E-cadherin dynamics by the Adaptor Protein Complex 1 during epithelial morphogenesis.. Mol Biol Cell.
- An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Kidneys, 11(1), 37-39. View this article in WRRO
- Evidence of paternal effects on telomere length increases in early life. Frontiers in Genetics, 13.
- Effect of robot-assisted radical cystectomy with intracorporeal urinary diversion vs open radical cystectomy on 90-day morbidity and mortality among patients with bladder cancer : a randomized clinical trial. JAMA. View this article in WRRO
- C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Science Alliance, 5(9), e202101276-e202101276.
- Management Of Acute Adrenal Insufficiency Related Adverse Events In Children With Congenital Adrenal Hyperplasia - Results Of An International Survey Of Specialist Centres. Hormone Research in Paediatrics.
- Functional and quality of life outcomes of localised prostate cancer treatments (Prostate Testing for Cancer and Treatment [ProtecT] study). BJU International. View this article in WRRO
- MO015: The Interaction of Gender and Genotype in the Development of Polycystic Liver Disease in ADPKD. Nephrology Dialysis Transplantation, 37(Supplement_3).
- FC029: A Multivariate Model Identifies Genotype, Hypertension and Kidney Length as Independent Baseline Predictors of Disease Progression in a Longitudinal Autosomal Dominant Polycystic Kidney Disease Patient Cohort. Nephrology Dialysis Transplantation, 37(Supplement_3).
- MO030: Familial clustering of a rare UMOD variant in undiagnosed hereditary nephropathy suggests the presence of a common ancestral founder mutation. Nephrology Dialysis Transplantation, 37(Supplement_3).
- Amino acid availability is not essential for lifespan extension by dietary restriction in the fly.. Journals of Gerontology, Series A, 77(11), 2181-2185.
- Transcriptional and post-transcriptional regulation of checkpoint genes on the tumour side of the immunological synapse. Heredity, 129(1), 64-74.
- Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection. PLoS Pathogens, 18(4).
- Can ketogenic dietary interventions slow disease progression in ADPKD : what we know and what we don't. Clinical Kidney Journal. View this article in WRRO
- SMN-deficient cells exhibit increased ribosomal DNA damage. Life Science Alliance, 5(8), e202101145-e202101145.
- Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver. The Lancet Gastroenterology & Hepatology.
- Reply to Benjamin Davies, Keith Kowalczyk RE: Zachary Klaassen, Emily Vertosick, Andrew J. Vickers, et al. Optimal Dissemination of Scientific Manuscripts via Social Media: A Prospective Trial Comparing Visual Abstracts Versus Key Figures in Consecutive Original Manuscripts. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.01.041. European Urology.
- Treatment of congenital adrenal hyperplasia in children aged 0-3 years: A retrospective multicenter analysis of salt supplementation, glucocorticoid and mineralocorticoid medication, growth and blood pressure. European Journal of Endocrinology.
- Addition of nintedanib or placebo to neoadjuvant gemcitabine and cisplatin in locally advanced muscle-invasive bladder cancer (NEOBLADE) : a double-blind, randomised, phase 2 trial. The Lancet Oncology, 23(5), 650-658. View this article in WRRO
- Loss of function of the neural cell adhesion molecule NrCAM regulates differentiation, proliferation and neurogenesis in early postnatal hypothalamic tanycytes. Frontiers in Neuroscience, 16.
- From WEDA to EDTA to ERA : 60 years of supporting European nephrology and counting. Nephrology Dialysis Transplantation.
- Measuring patient compliance with remote monitoring following discharge from hospital after major surgery (DREAMPath): protocol for a prospective observational study. JMIR Research Protocols, 11(4).
- The Amoebal Model for Macropinocytosis, 41-59.
- Müller glia maintain their regenerative potential despite degeneration in the aged zebrafish retina. Aging Cell, 21(4).
- Author Correction: STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena. Scientific Reports, 12(1).
- Neural crest-derived stem cells (NCSCs) obtained from dental-related stem cells (DRSCs) : a literature review on current knowledge and directions toward translational applications. International Journal of Molecular Sciences, 23(5). View this article in WRRO
- Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease. Cellular and Molecular Life Sciences, 79(3). View this article in WRRO
- DASL-HiCaP: Darolutamide augments standard therapy for localized very high-risk cancer of the prostate (ANZUP1801). a randomized phase 3 double-blind, placebo-controlled trial of adding darolutamide to androgen deprivation therapy and definitive or salvage radiation.. Journal of Clinical Oncology, 40(6_suppl), TPS284-TPS284.
- A phase 3, randomized, open-label, multicenter, global study of the efficacy and safety of durvalumab (D) + tremelimumab (T) + enfortumab vedotin (EV) or D + EV for neoadjuvant treatment in cisplatin-ineligible muscle-invasive bladder cancer (MIBC) (VOLGA).. Journal of Clinical Oncology, 40(6_suppl), TPS579-TPS579.
- Real-world evidence from a single U.K. cancer center for atezolizumab in second-line setting in advanced urothelial cancer: Moving beyond clinical trials.. Journal of Clinical Oncology, 40(6_suppl), 461-461.
- Zebrafish vascular quantification: a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis. Development, 149(3).
- Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399(10325), 665-676. View this article in WRRO
- A zebrafish reporter line reveals immune and neuronal expression of endogenous retrovirus. Disease Models & Mechanisms.
- Individualized everolimus treatment for tuberous sclerosis-related angiomyolipoma promotes treatment adherence and response. Clinical Kidney Journal. View this article in WRRO
- A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence. Current Biology.
- Robot assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy: Results from the iROC prospective randomised controlled trial. European Urology, 81, S1125-S1125.
- Study EV-104: Phase 1 study of intravesical enfortumab vedotin for treatment of patients with Non-Muscle Invasive Bladder Cancer (NMIBC) (Trial in Progress). European Urology, 81, S507-S507.
- The optimal dissemination of scientific manuscripts via social media: A prospective randomized trial comparing visual abstracts with key figures using consecutive original manuscripts published in European Urology. European Urology, 81, S142-S143.
- Adhesion-regulated junction slippage controls cell intercalation dynamics in an Apposed-Cortex Adhesion Model. PLoS Computational Biology, 18(1).
- The cross-talk between EGFR and E-Cadherin. Frontiers in Cell and Developmental Biology, 9. View this article in WRRO
- Single-cell analysis of early chick hypothalamic development reveals that hypothalamic cells are induced from prethalamic-like progenitors. Cell Reports, 38(3). View this article in WRRO
- Shaping axial identity during human pluripotent stem cell differentiation to neural crest cells.. Biochem Soc Trans.
- Impact of circ-0000221 in the pathogenesis of hepatocellular via modulation of miR-661–PTPN11 mRNA axis. Pharmaceutics, 14(1).
- Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 399(10320), 143-151. View this article in WRRO
- Optimal Dissemination of Scientific Manuscripts via Social Media: A Prospective Trial Comparing Visual Abstracts Versus Key Figures in Consecutive Original Manuscripts Published in European Urology. European Urology.
- Developing a Diagnostic Multivariable Prediction Model for Urinary Tract Cancer in Patients Referred with Haematuria: Results from the IDENTIFY Collaborative Study. European Urology Focus.
- Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection. BJS Open, 5(6).
- Metformin induces lactate accumulation and accelerates renal cyst progression in Pkd1-deficient mice. Human Molecular Genetics. View this article in WRRO
- Androgen elevation accelerates reproductive senescence in three-spined stickleback. Frontiers in Cell and Developmental Biology, 9. View this article in WRRO
- Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype. The American Journal of Human Genetics.
- Compensatory variability in network parameters enhances memory performance in the Drosophila mushroom body. Proceedings of the National Academy of Sciences, 118(49). View this article in WRRO
- Editorial: Neutrophil functions in host immunity, inflammation and tissue repair. Frontiers in Immunology, 12.
- Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration. PLoS ONE, 16(11). View this article in WRRO
- Moving the research forward : the best of British biology using the tractable model system Dictyostelium discoideum. Cells, 10(11).
- Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics. Proceedings of the National Academy of Sciences, 118(44).
- The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency : a case series. European Journal of Endocrinology, 185(5), 729-741.
- Defining factors associated with high-quality surgery following radical cystectomy : analysis of the British Association of Urological Surgeons cystectomy audit. European Urology Open Science, 33, 1-10.
- Origami: single-cell 3D shape dynamics oriented along the apico-basal axis of folding epithelia from fluorescence microscopy data. PLOS Computational Biology, 17(11). View this article in WRRO
- Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition. Nature Reviews Molecular Cell Biology, 22(12), 834-834.
- Quantifying endothelial cell proliferation in the zebrafish embryo. F1000Research, 10, 1032.
- Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.. Lancet Oncol.
- A role for Rad5 in ribonucleoside monophosphate (rNMP) tolerance. Life Science Alliance, 4(10), e202000966-e202000966.
- Fgf signalling triggers an intrinsic mesodermal timer that determines the duration of limb patterning. Nature Communications, 14(1).
- The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function. Nature Communications, 14(1).
- Long‐term health consequences of congenital adrenal hyperplasia. Clinical Endocrinology.
- Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study. JMIR Research Protocols, 12, e48014-e48014.
- Journey of a thousand miles: from ‘Manpo-Kei’ to the first steps-based physical activity recommendations. British Journal of Sports Medicine.
- Device-based measurement of physical activity in cardiovascular healthcare: possibilities and challenges. British Journal of Sports Medicine.
- Potential impact of wearables on physical activity guidelines and interventions: opportunities and challenges. British Journal of Sports Medicine.
- Glucocorticoid Receptor regulates protein chaperone, circadian clock and affective disorder genes in the zebrafish brain. Disease Models & Mechanisms.
- Identification of renal cyst cells of type I Nephronophthisis by single-nucleus RNA sequencing. Frontiers in Cell and Developmental Biology, 11, 1192935.
- Quality of Life in children and young people with Congenital Adrenal Hyperplasia – UK nationwide multicentre assessment. The Journal of Clinical Endocrinology & Metabolism.
- Using the Non-Adoption, Abandonment, Scale-Up, Spread, and Sustainability (NASSS) Framework to Identify Barriers and Facilitators for the Implementation of Digital Twins in Cardiovascular Medicine. Sensors, 23(14), 6333-6333.
- Diagnosis, treatment, and survival from kidney cancer: real‐world
NHS England data between 2013‐2019. BJU International. - A screen of pharmacologically active compounds to identify modulators of the Adgrg6/Gpr126 signalling pathway in zebrafish embryos. Basic & Clinical Pharmacology & Toxicology.
- PLA2G12A as a Novel Biomarker for Colorectal Cancer with Prognostic Relevance. International Journal of Molecular Sciences, 24(13), 10889-10889.
- Social and asocial learning in zebrafish are encoded by a shared brain network that is differentially modulated by local activation. Communications Biology, 6(1).
- Exercise Interventions for the Management of Sarcopenia: Possibilities and Challenges. Physical & Occupational Therapy In Geriatrics, 1-24.
- Barriers and facilitators to the implementation of guidelines in rare diseases: a systematic review. Orphanet Journal of Rare Diseases, 18(1).
- A Double‐Blind, Randomized, Placebo‐Controlled Trial of Ursodeoxycholic Acid (
UDCA) in Parkinson's Disease. Movement Disorders. - A median fin derived from the lateral plate mesoderm and the origin of paired fins. Nature.
- Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function. International Journal of Molecular Sciences, 24(10), 8806-8806.
- Early‐life telomere length predicts life‐history strategy and reproductive senescence in a threatened wild songbird. Molecular Ecology.
- Emergency and perioperative management of adrenal insufficiency in children and young people: British Society for Paediatric Endocrinology and Diabetes consensus guidance. Archives of Disease in Childhood.
- Unexpected phenotypic and molecular changes of combined glucocerebrosidase and acid sphingomyelinase deficiency. Disease Models & Mechanisms.
- Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. New England Journal of Medicine.
- Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease. Brain.
- Activated PI3K Delta Syndrome-1 mutations cause neutrophilia in zebrafish larvae. Disease Models & Mechanisms.
- Charting a Course for Smartphones and Wearables to Transform Population Health Research. Journal of Medical Internet Research, 25, e42449-e42449.
- Enhancer trap lines with
GFP driven by smad6b and frizzled1 regulatory sequences for the study of epithelial morphogenesis in the developing zebrafish inner ear. Journal of Anatomy. - Deciphering the roles of cell shape and Fat and Dachsous planar polarity in arranging the Drosophila apical microtubule network through quantitative image analysis. Molecular Biology of the Cell.
- A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus. eLife, 12.
- Diagnosis, treatment and survival from bladder, upper urinary tract and urethral cancers: Real world findings from
NHS England between 2013 and 2019. BJU International. - Rac1 controls cell turnover and reversibility of the involution process in postpartum mammary glands. PLOS Biology, 21(1), e3001583-e3001583.
- Katnip is required to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes. Molecular Biology of the Cell.
- Recommendations for hydrocortisone doses for emergency management and peri-operative care for childhood adrenal insufficiency. BSPED consensus guidelines. Endocrine Abstracts.
- Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor. eLife, 11.
- Regional variation in tolvaptan prescribing across England: national data and retrospective evaluation from an expert centre. Clinical Kidney Journal.
- The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages. Frontiers in Immunology, 13.
- An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. Acta Neuropathologica.
- Analysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry. Clinical Endocrinology.
- CORM-3 induces DNA damage through Ru(II) binding to DNA. Biochemical Journal.
- Neuroimaging Correlates of Cognitive Deficits in Wilson's Disease. Movement Disorders.
- Morphological, behavioral and cellular analyses revealed different phenotypes in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines. Human Molecular Genetics.
- Roscovitine Worsens Mycobacterium abscessus Infection by Reducing DUOX2-Mediated Neutrophil Response. American Journal of Respiratory Cell and Molecular Biology.
- Gene of the month: NKX3.1. Journal of Clinical Pathology.
- GCH1 deficiency activates brain innate immune response and impairs tyrosine hydroxylase homeostasis. The Journal of Neuroscience.
- An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Nephrology Dialysis Transplantation.
- Current management of acute adrenal insufficiency related adverse events in children- results of an international survey of specialist centres. Endocrine Abstracts.
- Analysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry. Endocrine Abstracts.
- The use of urinary steroid profiles in monitoring therapy in children with 21-hydroxylase deficiency - results from the CAH-UK cohort study. Endocrine Abstracts.
Chapters
- Zebrafish Larvae as an Experimental Model of Cryptococcal Meningitis, Methods in Molecular Biology (pp. 47-69). Springer US
- Animal Models in Monoclonal Immunoglobulin-Related Diseases, Paraproteinemia and Related Disorders (pp. 57-77). Springer International Publishing
- Imaging in Bladder Cancer Surgery, Robotic Urologic Surgery (pp. 627-637). Springer International Publishing
- Fish Macrophages, Principles of Fish Immunology (pp. 203-227). Springer International Publishing
- Prostate Cancer, Basic Urological Sciences (pp. 208-217). CRC Press
- Urothelial and Urethral Cancer, Basic Urological Sciences (pp. 189-207). CRC Press
Conference proceedings papers
- P73 Patients with polycystic liver disease have longer waiting times but better clinical outcomes following liver transplantation in the UK. Abstracts
- BS42 Characterising spatiotemporal membrane and F-actin dynamics in Kugeln, a novel endothelial membrane behaviour in the zebrafish cerebral vasculature. Basic science
- Shorter hospital stay with robotic surgery versus open surgery in bladder cancer. Medicom Conference Report EAU 2022, 1 July 2022 - 1 July 2022.
Posters
Preprints
- Macrophage subpopulation identity inDrosophilais modulated by apoptotic cell clearance and related signalling pathways, Cold Spring Harbor Laboratory.
- Tribbles1 and Cop1 cooperate to protect the host during in vivo mycobacterial infection, Cold Spring Harbor Laboratory.
- The optimal clutch size revisited: separating individual quality from the costs of reproduction, eLife Sciences Publications, Ltd.
- The optimal clutch size revisited: separating individual quality from the costs of reproduction, eLife Sciences Publications, Ltd.
- Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle, Cold Spring Harbor Laboratory.
- Determining the importance of the stringent response for methicillin-resistantStaphylococcus aureusvirulence using a zebrafish model of infection, Cold Spring Harbor Laboratory.
- Notch signalling influences cell fate decisions and HOX gene induction in axial progenitors, Cold Spring Harbor Laboratory.
- Stochasticity explains non-genetic inheritance of lifespan and apparent trade-offs between reproduction and ageing, Cold Spring Harbor Laboratory.
- A Stakeholder-Led Understanding of the Implementation of Digital Technologies Within Heart Disease Diagnosis: A Qualitative Study Protocol, Cold Spring Harbor Laboratory.
- Analysis of the Distal Urinary Tract in Larval and Adult Zebrafish Reveals Unrecognized Homology to the Human System, Cold Spring Harbor Laboratory.
- The importance of reaction norms in dietary restriction and ageing research, Cold Spring Harbor Laboratory.
- Neuroblastoma-associated chromosomal aberrations drive cell identity loss in human neural crest via disruption of developmental regulators, Cold Spring Harbor Laboratory.
- Asymmetric dimethylation of Ribosomal S6 Kinase 2 regulates its cellular localisation and pro-survival function, Cold Spring Harbor Laboratory.
- The formation and closure of macropinocytic cups in a model system, Cold Spring Harbor Laboratory.
- Rapamycin not Dietary Restriction improves resilience against pathogens: a meta-analysis, Cold Spring Harbor Laboratory.
- A PI(3,5)P2 probe reveals PIKfyve is required for Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes, Cold Spring Harbor Laboratory.
- A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo., Cold Spring Harbor Laboratory.
- A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus, Cold Spring Harbor Laboratory.
- The optimal clutch size revisited: separating individual quality from the costs of reproduction, Cold Spring Harbor Laboratory.
- TRANSCRIPTOMIC SIGNATURES OF TELOMERASE-DEPENDENT AND -INDEPENDENT AGEING, IN THE ZEBRAFISH GUT AND BRAIN, Cold Spring Harbor Laboratory.
- Exercise Interventions for the Management of Sarcopenia: Possibilities and Challenges, Research Square Platform LLC.
- HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A, Cold Spring Harbor Laboratory.
- Barriers and facilitators to the implementation of guidelines in rare diseases: A systematic review, Research Square Platform LLC.
- The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages, Cold Spring Harbor Laboratory.
- Rac1 controls cell turnover and mammary gland reversibility in post-partum involution, Cold Spring Harbor Laboratory.
- Bespoke data augmentation and network construction enable image classification on small microscopy datasets, Cold Spring Harbor Laboratory.
- An arginase 2 promoter transgenic illuminates anti-inflammatory signalling in zebrafish, Cold Spring Harbor Laboratory.
- A subset of gut leukocytes have telomerase-dependent “hyper-long” telomeres and require telomerase for function in zebrafish, Cold Spring Harbor Laboratory.
- Ubiquitinome analysis of articular cartilage post mechanical injury reveals a differential ubiquitination pattern of a subset of DUBs and proteins linked to the ERAD cellular response, Cold Spring Harbor Laboratory.
- Vaccines provide disproportional protection to the increased hospitalisation risk posed by the Delta variant of SARS-CoV2: a meta-analysis, Cold Spring Harbor Laboratory.
- The neural cell adhesion molecule NrCAM regulates development of hypothalamic tanycytes, Cold Spring Harbor Laboratory.
- Tetraspanin Cd9b plays a role in fertility in zebrafish, Cold Spring Harbor Laboratory.
- insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology, Cold Spring Harbor Laboratory.
- Multifaceted control of E-cadherin dynamics by the Adaptor Protein Complex 1 during epithelial morphogenesis, Cold Spring Harbor Laboratory.
- ChemChaste: Simulating spatially inhomogenous biochemical reaction-diffusion systems for modelling cell-environment feedbacks, Cold Spring Harbor Laboratory.
- Social and asocial learning in zebrafish are encoded by a shared brain network that is differentially modulated by local activation, Cold Spring Harbor Laboratory.
- C9orf72-derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons, Cold Spring Harbor Laboratory.