Gene Therapy Innovation Hub

Gene Therapy Innovation and Manufacturing Centre

Accelerating the development of gene therapies into life-changing treatments for patients.

Gene Therapy Innovation Hub logo

The Gene Therapy Innovation and Manufacturing Centre (GTIMC) has been formed as part of the Innovation Hubs for Gene Therapies. The network of Innovation Hubs for Gene Therapies is a new UK initiative designed to advance the clinical development of new genetic treatments through the production of clinical grade vectors, alongside translational support and regulatory advice. 

Artist's impression

The Sheffield Innovation Hub will dramatically broaden the scope of gene therapy research in the UK. The Sheffield centre brings together partners from the North of England, the Midlands and Wales to advance knowledge on gene therapies so that we can translate scientific discoveries into new and exciting treatments for patients.

What we do

Scientist conducting the process of Polymerase chain reaction (PCR) to amplify DNA by using a thermocycler to create samples - stock photo

Manufacturing

The GTIMC includes a new state-of-the-art GMP manufacturing facility that will support gene therapy projects emerging from UK universities. 

Manufacturing clinical grade AAVs

Improve Manufacturing Productivity. Quality Engineer inspecting product in production process at medical industry. - stock photo

Process Innovation

The hub will enable an extensive process innovation programme. We will coordinate with other Innovation Hubs for Gene Therapies for access to methodologies, develop new processes and ensure swift transition to commercial scale production.

Biomedical science postgraduate students in lab

Training and Skills

The hub offers opportunities for expanding training and skills through a newly established MSc course in advanced therapies, links to ATTC training, the apprenticeship community, and establishing a new PhD programme in this space.

MSc Advanced Cell and Gene Therapies 

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