Matthew Bursnall

School of Health and Related Research

Medical Statistician
+44 114 222 0889

Full contact details

Matthew Bursnall
School of Health and Related Research
Room 3.04, 3rd Floor
The Innovation Centre
217 Portobello
S1 4DP

I joined the CTRU in 2018, having previously worked as a statistician in the Department for Education and as an econometrician at the National Institute for Economic and Social Research. I mainly work on the statistical design and analysis of Randomised Controlled Trials but am also involved in observational studies and quantitative social research.

Research interests

I have an interest in the following research:

  • Sample size estimation for studies with clustering in a single arm 
  • Assumptions for the inter-class correlation coefficient in cluster trials in the absence of previous evidence 
  • Unbiased estimation of treatment effects in step-up trials where group-based treatment intensity is increased depending on a post-randomisation interim outcome.
  • Simulating trials using Causal analysis within a Target Trial Framework

Current projects

  • AWARE IBD - Putting people with inflammatory bowel disease (IBD) in control of their care
  • COMMEND - COMmitment therapy for people with Motor nEuroN Disease
  • MissionEB - Mesenchymal Intravenous Stromal cell InfuSIONs in children with recessive dystrophic Epidermolysis Bullosa
  • ORION - RadiO fRequency ablatION for haemorrhoids
  • StarMS - Autologous Stem Cell Transplantation versus Alemtuzumab or OcRelizumab or Ofatumumab or Cladribine in Relapsing-Remitting Multiple Sclerosis

Recent projects

  • ESEE Steps - Enhancing Social-Emotional Health and Wellbeing in the Early Years
  • ISOCIALISE - Investigating SOcial Competence and Isolation in children with Autism taking part in Lego®-based therapy clubs In School Environments
  • PRIEST - Pre-hospital Pandemic Respiratory Infection Emergency System Triage
  • VTEAM - Venous Thromboembolism Assessment Model Study

Show: Featured publications All publications

Journal articles

Conference proceedings papers

All publications

Journal articles

Conference proceedings papers

Website content

  • Bursnall MC SAP changing mindsets EEF. RIS download Bibtex download
  • Bursnall M Embedding Formative Assessment SAP. RIS download Bibtex download

Scholarly editions

  • Bursnall M, Nafilyan V & Speckesser S An analysis of the duration and achievement of apprenticeships in England. RIS download Bibtex download


Professional activities and memberships

I am the independent statistician on the Data Monitoring Committee or Trial Steering Committees for three trials: 

  • TBI Sertraline - A multi-centre, placebo-controlled, double-blind, randomised controlled trial of the clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury.
  • D-CODE – a single-site feasibility study of improving symptoms in patients with Crohn’s disease using Vitamin D Supplementation as an Adjunct Therapy. 
  • PROSPECT - A multi-centre, two-arm Phase III single-blind randomised controlled trial (RCT) of the clinical cost-effectiveness of targeted psychological therapy for suicidal male prisoners by enhancing access to therapies.