Carla Girling

BSc, MSc

School of Medicine and Population Health

Trial Manager

Research Associate

c.girling@sheffield.ac.uk
+44 114 222 4027

Room 2.13, The Innovation Centre

Full contact details

Carla Girling
School of Medicine and Population Health
Room 2.13
The Innovation Centre
217 Portobello
Sheffield
S1 4DP

Profile: My academic interest is the implementation of evidence-based medicine into clinical practice. I am currently managing the DENIM Trial (Delivering Effective Non-Invasive ventilation in MND), a hybrid type 3 implementation trial, with a stepped wedged cross-sectional design. DENIM’s implementation strategy is based on Normalisation Process Theory. The implementation will support home ventilation teams to deliver a new intensive non-invasive ventilation (NIV) service, which includes telemonitoring. DENIM aims to understand whether this can increase the number of hours people with Motor Neuron Disease (MND) use their NIV. DENIM will open to recruitment in May 2025, in 12 UK NHS sites that deliver home ventilation services for people with MND.

Previously, I managed the ORION trial (NIHR, Health Technology Assessment 131861), a pragmatic multicentre randomisation-controlled trial to assess whether radiofrequency ablation (using the Rafaelo® device) is at least as good as existing methods for the surgical treatment of haemorrhoids. I also managed a multi-centre quality improvement and implementation study, funded by NHS England, to transform the delivery of Cystic Fibrosis (CF) care in the UK. This included a cohort Multiple Randomised Controlled Trial (or 'Trials within Cohorts') platform, with a focus on behaviour change interventions. As part of the implementation of CFHealthHub into CF care, I helped design and delivered quality improvement workshops to NHS staff.

Prior to joining CTRU, I was a Research Assistant for Leeds and York Partnership NHS Foundation Trust. During this time, I conducted National Institute of Health Research Portfolio projects across a range of adult mental health conditions.

Qualifications: BSc (Hons) Psychology
MSc Psychological Research Methods

Research interests: Implementation of evidence based practices in healthcare, Implementation Science

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Hoo ZH, Totton N, Waterhouse S, Lewis J, Girling C, Bradburn M, Arden MA, Whelan P, Ainsworth J, Dawson S , Millward S et al (2021) Real-world adherence among adults with cystic fibrosis is low – a retrospective analysis of the CFHealthHub digital learning health system. Chest. View this article in WRRO
Dawson S, Cowap L, Clark-Carter D & Girling C-J (2020) Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis. Cochrane Database of Systematic Reviews. View this article in WRRO
Levita L, Salas Duhne PG, Girling C & Waller G (2016) Facets of clinicians' anxiety and the delivery of cognitive behavioral therapy. Behaviour Research and Therapy, 77, 157-161. View this article in WRRO

Conference proceedings papers

Girling C, Hind D, Arden MA & Wildman MJ (2019) Developing an implementation strategy for the use of objective adherence data in routine clinical practice: a case study in cystic fibrosis clinics. IMPLEMENTATION SCIENCE, Vol. 14 (pp 4-5)

All publications

Journal articles

Dawson S, Girling C-J, Cowap L & Clark-Carter D (2023) Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis. Cochrane Database of Systematic Reviews, 2023(3). View this article in WRRO
Girling C, Lee MJ, Vimalchandran D, Jayne DJ, Stancliffe S, Wailoo A, Bradburn M, Hind D, Bursnall M, Robinson LK & Brown SR (2022) Protocol for the ORION trial (RadiO fRequency ablatION for haemorrhoids): a randomised controlled trial. Techniques in Coloproctology.
Bevan A, Hoo ZH, Totton N, Girling C, Davids IR, Whelan P, Antrobus S, Ainsworth J, Buchan I, Anderson A , Bourke S et al (2022) Corrigendum to “Using a learning health system to understand the mismatch between medicines supply and actual medicines use among adults with cystic fibrosis” [J Cyst Fibros (2022), 21/2, 323-331]. Journal of Cystic Fibrosis.
Girling C, Packham A, Robinson L, Arden MA, Hind D & Wildman MJ (2022) Implementing the use of objective medication adherence data in routine clinical practice via the digital CFHealthHub platform : situation analysis and strategy development using the theoretical domains framework. Implementation Science Communications, 3(1).
Totton N, Bradburn M, Hoo ZH, Lewis J, Hind D, Girling C, Shepherd E, Nightingale J, Daniels T, Dewar J , Dawson S et al (2021) Prospectively predicting Pseudomonas aeruginosa infection/s using routine data from the UK cystic fibrosis register. Health Science Reports, 4(4). View this article in WRRO
Bevan A, Hoo ZH, Totton N, Girling C, Davids IR, Whelan P, Antrobus S, Ainsworth J, Buchan I, Anderson A , Bourke S et al (2021) Using a learning health system to understand the mismatch between medicines supply and actual medicines use among adults with cystic fibrosis. Journal of Cystic Fibrosis.
Hoo ZH, Totton N, Waterhouse S, Lewis J, Girling C, Bradburn M, Arden MA, Whelan P, Ainsworth J, Dawson S , Millward S et al (2021) Real-world adherence among adults with cystic fibrosis is low – a retrospective analysis of the CFHealthHub digital learning health system. Chest. View this article in WRRO
Dawson S, Cowap L, Clark-Carter D & Girling C-J (2020) Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis. Cochrane Database of Systematic Reviews. View this article in WRRO
Carolan C, Lowther M, Clarke C, Waterhouse S, Girling C, Strowbridge K, Harrison S, Edenborough F, Rachel C & Wildman M (2019) ePS5.06 Quality improvement within a learning health system: using PDSA cycles to embed a digital behaviour change platform, CFHealthHub, in routine care. Journal of Cystic Fibrosis, 18, S52-S52.
Clarke C, Carolan C, Lowther M, Waterhouse S, Strowbridge K, Harrison S, Girling C, Edenborough F, Curley R & Wildman M (2019) P432 How physiotherapists improved prescription accuracy for nebuliser treatment: using click analytics from CFHealthHub, a digital adherence system, to monitor quality improvement. Journal of Cystic Fibrosis, 18, S179-S179.
Carolan C, Clarke C, Lowther M, Girling C, Harrison S, Edenborough F, Curley R & Wildman M (2019) P433 Supporting patients to move from rescue to prevention: meeting patients on their own terms - a preliminary evaluation of out of hours adherence telephone support offered to cystic fibrosis patients using the digital health system CFHealthhub. Journal of Cystic Fibrosis, 18, S179-S180.
Levita L, Salas Duhne PG, Girling C & Waller G (2016) Facets of clinicians' anxiety and the delivery of cognitive behavioral therapy. Behaviour Research and Therapy, 77, 157-161. View this article in WRRO
Girling C, Davids I, Totton N, Arden MA, Hind D & Wildman MJ () Changing practice in cystic fibrosis: Implementing objective medication adherence data at every consultation, a learning health system and quality improvement collaborative. Learning Health Systems.
Brown SR, Girling C, Thapa Magar H, Chaudry A, Bhatti B, Sayers AE & Hind D () Guidelines, guidelines and more guidelines for haemorrhoid treatment: A review to sort the wheat from the chaff. Colorectal Disease.

Conference proceedings papers

Bevan A, Dawson S, Hall J, Davids I, Girling C, Cross E & Wildman M (2022) P64 Using the CFHealthHub learning health system to understand the experiences of adults with cystic fibrosis of obtaining repeat supplies of nebulised medicines: results of a national survey. ‘Training Day’ – Learning from CF patients
Girling C, Hind D, Arden MA & Wildman MJ (2019) Developing an implementation strategy for the use of objective adherence data in routine clinical practice: a case study in cystic fibrosis clinics. IMPLEMENTATION SCIENCE, Vol. 14 (pp 4-5)
Girling C, Hind D, Arden MA & Wildman MJ (2019) Developing an implementation strategy for the use of objective adherence data in routine clinical practice: a case study in cystic fibrosis clinics. IMPLEMENTATION SCIENCE, Vol. 14

Posters

Hoo ZH, Totton N, Waterhouse S, Hind D, Girling C, Bradburn M, Shepherd E, Nightingale JA, Daniels TV, Dewar J , Saini G et al (2019) ePS5.05 Understanding objective adherence to preventative inhaled therapies at a centre level for quality improvement - a CFHealthHub (CFHH) improvement collaborative study.

Preprints

Girling C, Packham A, Robinson L, Arden MA, Hind D & Wildman MJ () Implementing the use of objective medication adherence data in routine clinical practice via the digital CFHealthHub platform: situation analysis and strategy development using the theoretical domains framework, Research Square Platform LLC. View this article in WRRO

Research group

Current projects

Delivering Effective Non-Invasive ventilation in MND- DENIM Trial (NIHR158715)

Previous projects

RadiO fRequency ablatION for haemorrhoids (ORION) (NIHR131861)
CFHealthHub Data Observatory – A Quality Improvement project and Trial within Cohort platform for Cystic Fibrosis
ASTIC lite - Autologous Stem cell Transplantation In refractory Crohn’s disease – Low Intensity Therapy Evaluation.

Teaching interests

I am involved in various teaching activities within the faculty, including:

HAR6030 Introduction to Research Methods
MBChB 2, SSC Research Attachment, Undergraduate Medical Students
Personal tutor to masters level students
HAR 679 Masters dissertation module tutor and dissertation supervisor

Teaching activities: I am involved in various teaching activities within the faculty, including:

HAR6030 Introduction to Research Methods
MBChB 2, SSC Research Attachment, Undergraduate Medical Students
Personal tutor to masters level students
HAR 679 Masters dissertation module tutor and dissertation supervisor