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29 June 2021

Osteoporosis drug could have the potential to increase healthspans for all

Life expectancies are increasing but healthspans are not increasing at the same rate. One solution could be a new type of drug that targets the root cause of ageing and age related disease, called a geroprotector.

9 June 2021

Drugs to stabilise plaques could prevent stroke

Drugs which target white blood cells and stabilise atherosclerotic plaques could be used to help prevent strokes, according to research presented today at the British Cardiovascular Society conference.

2 June 2021

Paving the way for the use of controlled heat as a therapeutic adjunct to topoisomerase targeting therapeutics.

In this paper, we show that hyperthermia suppresses the level of topoisomerase mediated single- and double-strand breaks induced by exposure to topoisomerase poisons.

13 May 2021

Sheffield u3a members to play active role in Healthy Lifespan Institute Research

The Healthy Lifespan Institute and Sheffield u3a (formerly University of the Third Age) have formed a partnership to ensure research into healthy ageing incorporates the lived experiences of older people.

DNA string with clipping path against black background

New paper in Nature Communications: Hypoxia-induced SETX links replication stress with the unfolded protein response

In the absence of hypoxia-induced SETX, R-loop levels increase, DNA damage accumulates, and DNA replication rates decrease. This suggests that, SETX plays a role in protecting cells from DNA damage induced during transcription in hypoxia.

18 June 2021

The Healthy Lifespan Institute presents, HELSI bites, a series of diverse, accessible lunchtime talks about research into healthy ageing.

HELSI Bites series launched

An engaging series of lunchtime talks on a diverse range of accessible topics has been launched by the Healthy Lifespan Institute. Just grab your lunch and listen in to a range research related to healthy ageing across the lifecourse.

19 April 2021

Grandson and grandfather laughing while laying on grass

Join our webinar

Join us for a lively discussion on the coming epidemic of chronic health conditions and frailty associated with an ageing population. And, how to prevent it.

Part of the Festival of Debate, the largest annual politics festival in the UK.

16 April 2021

All Party Parliamentary Group for Longevity

New report, Levelling Up Health, from from the APPG for Longevity is out today

As proud partners of the APPG we support its call for a reimaged approach to public health and a reduction in health inequalities. Our research into the social determents of health throughout the lifecourse has contributed to the work of the APPG.

9 April 2021

Young woman using futuristic digital interface display on dark background.

University of Sheffield team receive award to use Artificial Intelligence (AI) to tackle multimorbidity in South Yorkshire

Researchers have been awarded an £118,500 NIHR Development Award to establish frameworks for a new AI tool to analyse multiple long-term conditions and multimorbidity in South Yorkshire and Bassetlaw.

31 March 2021