Core Facilities

The Medical School possesses a wide range of up-to-date equipment to enable us to service an internationally leading research organisation. These facilities are available for collaborative projects as well as contract research.


Biorepository

Sheffield Biorepository
The biorepository is a fully compliant, safe and secure, storage facility for all human tissues. It offers help and advice to facilitate compliance with Human Tissue Authority guidelines, and provides tissue banking cryostorage areas.


cytometery

Flow Cytometry
This facility boasts 4 analysers, one of which is a start of the art 4 laser 13 colour detector machine, there is also a 3 laser 9 colour cell sorter and a 2 laser system capable of quantifying multiple soluble proteins in small sample volumes.


genetics

Genomics Facility
This facility offers high throughput cap-sequencing on an ABI 3730/48 platform, microsatellite and snp genotyping; and houses two ABI 7900 platforms, offering RT-PCR and phenotyping of mRNA by TaqMan.


histology

Histology
This facility offers expertise in immunohistochemistry, in-situ hybridization, tissue banking, frozen sections, and image cytometry for ploidy analysis.


microarray

Microarray
This facility consists of an Agilent 2100 bioanalyser to examine RNA integrity and concentration and an Affymetrix Gene Chip hybridisation system allowing us to offer a range of expression and SNP array analysis. Gene Chip expression arrays are now available for a large number of organisms.


robotics

High Throughput Robotic Screening
This facility consists of two highly specialised Genetix robots, Q-bot and MegaPix, that are able to perform a variety of liquid handling, colony picking and re-arraying (cherry picking) routines.This system is capable of processing thousands of samples per day.


Microscope Lab

Microscopy Facility
The core Microscopy facilities in the Medical School provide a comprehensive biological imaging service to all departments.


Other Facilities

skelet.AL

skelet.AL (former Bone Analysis lab)
The bone analysis lab was established in 2003 to provide members of the Musculoskeletal theme and academics throughout the medical school with access to contemporary approaches to analysing bone.