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DNA strands

Sheffield spinout takes major step towards advancing pioneering treatments for Hereditary Spastic Paraplegia (HSP)

BlackfinBio Limited is a spinout company from the University of Sheffield set to pioneer novel therapies for rare genetic neurological diseases.

Image of motor neurones

Groundbreaking EXPERTS-ALS study for MND treatments

The EXPErimental medicine Route To Success in ALS (EXPERTS-ALS) project aims to rapidly screen potential drugs for evidence that they can slow down damage to the nervous system occurring in people with motor neuron disease
Professor Mimoun Azzouz holding a petri dish

Comment: Turning the biggest disappointment of a career into a new era for UK gene therapy manufacturing

Professor Mimoun Azzouz discusses career challenges before opening the Gene Therapy Innovation and Manufacturing Centre (GTIMC) at the University of Sheffield.
Medical illustration of a brain with stroke symptoms

Our 2024 research highlights

As the year comes to a close, we want to take a moment to reflect on and celebrate some of our research news stories from 2024.
Neuron cells system. Conceptual medical image. Glowing synapse. Healthcare concept.

Encouraging early study for investigational drug in people with motor neurone disease

The University of Sheffield with Sheffield Teaching Hospitals NHS Foundation Trust is the only site in the UK to have participated in an international clinical trial for an investigational drug in people with a form of motor neurone disease (MND)
Neuron cells system - 3d rendered image of Neuron cell network on black background

New insights from first clinical trial of potential treatment for motor neurone disease

Results from a randomised clinical trial have shown that a potential new treatment can help control the immune response of patients with motor neurone disease (MND), which could reduce further damage in the brain and spinal cord.
Human brain and waves, conceptual computer artwork.

Scientists identify how the brain regulates its own signalling

Researchers from the University of Sheffield have furthered our understanding of brain function by revealing how stable levels of neuronal signalling are maintained in fruit flies.
Researchers in SITraN lab

MND awareness day 2020 - research in Sheffield

On 21 June, we are recognising motor neurone disease (MND) awareness day and the impact that this disease has on people from all over the world.
The Big 30 - a collage of images showing a variety of activities

Big 30 fundraising challenge supporting Parkinson’s research

From doing 30 sit-ups to running 30 miles, we are inviting staff, students and members of the public to do 30 things this month in support of Parkinson's research.