David White

MPH (HSR)

School of Health and Related Research

Senior Research Fellow/ Portfolio Lead

d.a.white@sheffield.ac.uk
+44 114 222 0807

+44 114 222 0870 (Fax)

2028, Regent Court (ScHARR)

Full contact details

David White
School of Health and Related Research
2028
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA

Profile

I joined the Clinical Trials Research Unit in 2009. I currently assist investigators in the design and costing of clinical research and oversee the CTRU’s involvement in funded studies. I also have joint oversight of the Quality Assurance activities for the Unit.

Before joining the University I worked at the University of Oxford supporting clinical trials in the Department of Primary Care.

Current and recent projects:

NIHR HTA - 15/35/03 - Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM) trial
NIHR HTA – 14/08/45 - A Multicentre Randomised Controlled Trial of Induced Endometrial Scratch in Women Undergoing First Time IN Vitro Fertilisation (IVF)
NIHR HTA – 16/81/01 - A feasibility study and randomised controlled trial of acceptance and COMmitment therapy for people with Motor nEuroN Disease (COMMEND)
NIHR HS&DR – 15/136/07 - Multiple Symptoms Study 3: pragmatic trial of a community based clinic for patients with persistent (medically unexplained) physical symptoms
NIHR PGfAR - RP-PG-1016-20006 - A programme to develop and evaluate a complex intervention to achieve a high calorie diet for people with Amyotrophic Lateral Sclerosis (HighCALS)
Horizon 2020 - 755094 - Safety and efficacy of tauroursodeoxycholic acid as add-on treatment in patients affected by amyotrophic lateral sclerosis (TUDCA-ALS)¬
NIHR HTA - NIHR128969 - HELP Infertility? (Hysteroscopic Excision of Leiomyoma and Polyp in Infertility): two randomised controlled trials
NIHR HTA - NIHR128137 - STOP-OHSS (Shaping and Trialling Outpatient Protocols for Ovarian Hyper-Stimulation Syndrome): A feasibility study and randomised controlled trial, with internal pilot, to assess the clinical and cost effectiveness of earlier active management of OHSS

Research interests

Controlled clinical trials
Trials methodology, planning and implementation
Clinical Trials of Investigational Medicinal Products (CTIMPs)

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Metwally M, Chatters R, Dimairo M, Walters S, Pye C, White D, Bhide P, Chater T, Cheong Y, Choudhary M , Child T et al (2021) A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI.. Hum Reprod.
Selvarajah D, Petrie J, White D, Julious S, Bortolami O, Cooper C, Bradburn M, Loban A, Bowler H, Swaby L , Sutherland K et al (2018) Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial. Trials, 19(1), 578-578. View this article in WRRO
Heller S, White D, Lee E, Lawton J, Pollard D, Waugh N, Amiel S, Barnard K, Beckwith A, Brennan A , Campbell M et al (2017) A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
Heller S, Amiel S, Campbell M, Choudhary P, Cooper C, Dimairo M, Elliott J, Hammond P, Lee E, Lindsay R , Waugh N et al (2017) Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356. View this article in WRRO
Gilbody S, Brabyn S, Lovell K, Kessler D, Devlin T, Smith L, Araya R, Barkham M, Bower P, Cooper C , Knowles S et al (2017) Telephone-supported computerised cognitive–behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial. The British Journal of Psychiatry, 210(5), 362-367. View this article in WRRO
Lawton J, White D, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
White D & Hind D (2015) Projection of participant recruitment to primary care research: a qualitative study. Trials, 16(1). View this article in WRRO
Lawton J, Kirkham J, White D, Rankin D, Cooper C & Heller S (2015) Uncovering the emotional aspects of working on a clinical trial: a qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16(1). View this article in WRRO
Gilbody S, Littlewood E, Hewitt C, Brierley G, Tharmanathan P, Araya R, Barkham M, Bower P, Cooper C, Gask L , Kessler D et al (2015) Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial. BMJ, 351. View this article in WRRO
White D, Waugh N, Elliott J, Lawton J, Barnard K, Campbell MJ, Dixon S & Heller S (2014) The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ Open, 4(9), e006204-e006204. View this article in WRRO

All publications

Journal articles

Chatters R, White D, Pye C, Petrovic A, Sizer A, Kumar P & Metwally M (2021) Experiences of trial participants and site staff of participating in and running a large randomised trial within fertility (the endometrial scratch trial): a qualitative interview study. BMJ Open, 11(9), e051698-e051698.
Metwally M, Chatters R, Dimairo M, Walters S, Pye C, White D, Bhide P, Chater T, Cheong Y, Choudhary M , Child T et al (2021) A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI.. Hum Reprod.
Bradburn MJ, Lee EC, White DA, Hind D, Waugh NR, Cooke DD, Hopkins D, Mansell P & Heller SR (2020) Treatment effects may remain the same even when trial participants differed from the target population. Journal of Clinical Epidemiology. View this article in WRRO
Biggs K, Hind D, Gossage-Worrall R, Sprange K, White D, Wright J, Chatters R, Berry K, Papaioannou D, Bradburn M , Walters SJ et al (2020) Challenges in the design, planning and implementation of trials evaluating group interventions. Trials, 21. View this article in WRRO
Essat M, Archer R, Williams I, Zarotti N, Coates E, Clowes M, Beever D, Hackney G, White S, Stavroulakis T , White D et al (2019) Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system : a systematic review. Clinical Nutrition. View this article in WRRO
Zarotti N, Coates E, McGeachan A, Williams I, Beever D, Hackney G, Norman P, Stavroulakis T, White D, White S , Halliday V et al (2019) Health care professionals’ views on psychological factors affecting nutritional behaviour in people with motor neuron disease : a thematic analysis. British Journal of Health Psychology. View this article in WRRO
Selvarajah D, Petrie J, White D, Julious S, Bortolami O, Cooper C, Bradburn M, Loban A, Bowler H, Swaby L , Sutherland K et al (2018) Multicentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial. Trials, 19(1), 578-578. View this article in WRRO
Pollard DJ, Brennan A, Dixon S, Waugh N, Elliott J, Heller S, Lee E, Campbell M, Basarir H & White D (2018) Cost-effectiveness of insulin pumps compared with multiple daily injections both provided with structured education for adults with type 1 diabetes: a health economic analysis of the Relative Effectiveness of Pumps over Structured Education (REPOSE) randomised controlled trial. BMJ Open, 8(4). View this article in WRRO
Heller S, White D, Lee E, Lawton J, Pollard D, Waugh N, Amiel S, Barnard K, Beckwith A, Brennan A , Campbell M et al (2017) A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technology Assessment, 21(20), 1-278. View this article in WRRO
Heller S, Amiel S, Campbell M, Choudhary P, Cooper C, Dimairo M, Elliott J, Hammond P, Lee E, Lindsay R , Waugh N et al (2017) Relative effectiveness of insulin pump treatment over multiple daily injections and structured education during flexible intensive insulin treatment for type 1 diabetes: cluster randomised trial (REPOSE). BMJ, 356. View this article in WRRO
Gilbody S, Brabyn S, Lovell K, Kessler D, Devlin T, Smith L, Araya R, Barkham M, Bower P, Cooper C , Knowles S et al (2017) Telephone-supported computerised cognitive–behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial. The British Journal of Psychiatry, 210(5), 362-367. View this article in WRRO
Lawton J, White D, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment: qualitative study. Trials, 18. View this article in WRRO
Brabyn S, Araya R, Barkham M, Bower P, Cooper C, Duarte A, Kessler D, Knowles S, Lovell K, Littlewood E , Mattock R et al (2016) The second Randomised Evaluation of the Effectiveness, cost-effectiveness and Acceptability of Computerised Therapy (REEACT-2) trial: does the provision of telephone support enhance the effectiveness of computer-delivered cognitive behaviour therapy? A randomised controlled trial.. Health Technology Assessment, 20(89), 1-64. View this article in WRRO
Lawton J, Kirkham J, Rankin D, White DA, Elliott J, Jaap A, Smithson WH, Heller S, Gianfrancesco C, Gordon V , Greaves L et al (2016) Who gains clinical benefit from using insulin pump therapy? A qualitative study of the perceptions and views of health professionals involved in the Relative Effectiveness of Pumps over MDI and Structured Education (REPOSE) trial. Diabetic Medicine, 33(2), 243-251.
White D & Hind D (2015) Projection of participant recruitment to primary care research: a qualitative study. Trials, 16(1). View this article in WRRO
Lawton J, Kirkham J, White D, Rankin D, Cooper C & Heller S (2015) Uncovering the emotional aspects of working on a clinical trial: a qualitative study of the experiences and views of staff involved in a type 1 diabetes trial. Trials, 16(1). View this article in WRRO
Gilbody S, Littlewood E, Hewitt C, Brierley G, Tharmanathan P, Araya R, Barkham M, Bower P, Cooper C, Gask L , Kessler D et al (2015) Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial. BMJ, 351. View this article in WRRO
Lawton J, Kirkham J, Rankin D, Barnard K, Cooper CL, Taylor C, Heller S & Elliott J (2014) Perceptions and experiences of using automated bolus advisors amongst people with type 1 diabetes: A longitudinal qualitative investigation. Diabetes Research and Clinical Practice, 106(3), 443-450. View this article in WRRO
White D, Waugh N, Elliott J, Lawton J, Barnard K, Campbell MJ, Dixon S & Heller S (2014) The Relative Effectiveness of Pumps Over MDI and Structured Education (REPOSE): study protocol for a cluster randomised controlled trial. BMJ Open, 4(9), e006204-e006204. View this article in WRRO
White S, Zarotti N, Beever D, Bradburn M, Norman P, Coates E, Stavroulakis T, White D, McGeachan A, Williams I , Hackney G et al () The nutritional management of people living with Amyotrophic Lateral Sclerosis (ALS): A national survey of dietitians. Journal of Human Nutrition and Dietetics.
Littlewood E, Duarte A, Hewitt C, Knowles S, Palmer S, Walker S, Andersen P, Araya R, Barkham M, Bower P , Brabyn S et al () A randomised controlled trial of computerised cognitive behaviour therapy for the treatment of depression in primary care: the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial. Health Technology Assessment, 19(101), 1-174. View this article in WRRO
Weeks K, Gould R, McDermott C, Lynch J, Goldstein L, Graham C, McCracken L, Serfaty M, Howard R, Al-Chalabi A , White D et al () Needs and preferences for psychological interventions of people with motor neuron disease. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. View this article in WRRO
Coates E, Zarotti N, Williams I, White S, Halliday V, Beever D, Hackney G, Stavroulakis T, White D, Norman P & McDermott C () Patient, carer and healthcare professional perspectives on increasing calorie intake in Amyotrophic Lateral Sclerosis. Chronic Illness.
Coates E, Zarotti N, Williams I, White S, Halliday V, Beever D, Hackney G, Stavroulakis T, White D, Norman P & McDermott C () Patient, carer and healthcare professional perspectives on increasing calorie intake in Amyotrophic Lateral Sclerosis. Chronic Illness.

Conference proceedings papers

White D, Lawton J, Rankin D, Elliott J, Taylor C, Cooper C, Heller S & Hallowell N (2017) Staff experiences of closing out a clinical trial involving withdrawal of treatment : qualitative study. Trials, Vol. 18(Suppl 1) (pp 91-91). Liverpool, UK, 7 May 2017 - 10 May 2017. View this article in WRRO
White D & Hind D (2015) Projection of participant recruitment to primary care research. Trials, Vol. 16(S2)