Professor Stephen Walters
BSc, PGCE, MSc, PhD, CStat.
School of Health and Related Research
Professor of Medical Statistics and Clinical Trials
s.j.walters@sheffield.ac.uk
+44 114 222 0730
+44 114 222 0730
+44 114 272 4095
(Fax)
Regent Court (ScHARR)
Full contact details
Professor Stephen Walters
School of Health and Related Research
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
School of Health and Related Research
Regent Court (ScHARR)
30 Regent Street
Sheffield
S1 4DA
- Profile
-
I graduated with a degree in Mathematics and Economics. This was followed by a PGCE and an MSc in Medical Statistics and Information Technology. My PhD involved using computer intensive statistical methods for estimating sample sizes and analysing quality of life outcomes. I joined ScHARR in January 1995. I was promoted to Senior Lecturer in 2003; Reader in 2008 and to a Personal Chair in 2009. I was the first Director of the Design, Trials and Statistics section in ScHARR from 2012-18.
I am a Chartered Statistician with over 27 years’ experience of health services research and technology assessment. The main focus of my research has been in the design, conduct, analysis, and reporting of trials of complex interventions; and the design, assessment, analysis and interpretation of patient reported outcomes in clinical trials. I work with clinicians from a variety of backgrounds to develop pragmatic clinical trial designs to capture the effectiveness and cost-effectiveness of a variety of health technologies. I have been co-investigator for more than 30 randomised controlled trials.
From 2018 to 2022 I was National Institute for Health Research (NIHR) Senior Investigator. I have been a member of the NIHR Health Technology Assessment (HTA) Clinical Evaluation and Trials Board (2011-17) and the East Midlands Regional Funding Committee for the NIHR Research for Patient Benefit Pogramme (2011-2012). I have also been a member of the National Institute for Health and Care Excellence (NICE) Public Health Interventions Advisory Committee (2008-2013).
I have co-authored over 330 publications (including 200 in refereed journals and 5 books, with over 25,000 copies sold). The majority of my peer-reviewed journal articles have been applied research, with the emphasis on the evaluation of new services. I have been a co-applicant, statistical advisor and collaborator on 74 funded Health Service Research projectswith a total income value of £49.1 million.
- Research interests
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- Design, conduct, analysis, and reporting of pragmatic trials of complex interventions.
- Design, assessment, analysis and interpretation of studies with Health Related Quality of Life (HRQoL) outcome measures. See 'Quality of life outcomes in clinical trials and health care evaluation: a practical guide to analysis and interpretation'.
- Health Services Research and Technology Assessment.
- Cluster RCTs and clustering by health professional in individually randomised trials.
- Study design and sample size determination.
- Publications
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Show: Featured publications All publications
Featured publications
Books
- Medical Statistics: A Textbook for the Health Sciences, 5th Edition. Wiley-Blackwell.
- How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research. John Wiley & Sons Ltd..
Journal articles
- An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia : the Journeying through Dementia RCT. Health Technology Assessment, 26(24), 1-151.
- The Journeying through Dementia psychosocial intervention versus usual care study: a single-blind, parallel group, phase 3 trial. The Lancet Healthy Longevity, 3(4), e276-e285.
- Association of task-shared psychological interventions with depression outcomes in low- and middle-income countries : a systematic review and individual patient data meta-analysis. JAMA Psychiatry.
- Recruitment, consent and retention of participants in randomised controlled trials : a review of trials published in the National Institute for Health Research (NIHR) Journals Library (1997–2020). BMJ Open, 12(2). View this article in WRRO
- Statistical analysis of publicly funded cluster randomised controlled trials : a review of the National Institute for Health Research Journals Library. Trials, 23(1). View this article in WRRO
- Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation : RCT and systematic review. Health Technology Assessment, 26(10), 1-211. View this article in WRRO
- An intervention to support adherence to inhaled medication in adults with cystic fibrosis : the ACtiF research programme including RCT. Programme Grants for Applied Research, 9(11), 1-146.
- Self-management intervention to reduce pulmonary exacerbations by supporting treatment adherence in adults with cystic fibrosis: a randomised controlled trial. Thorax. View this article in WRRO
- Comprehensive review of statistical methods for analysing patient-reported outcomes (PROs) used as primary outcomes in randomised controlled trials (RCTs) published by the UK’s Health Technology Assessment (HTA) journal (1997–2020). BMJ Open, 11(9). View this article in WRRO
- A breakthrough series collaborative to increase patient participation with hemodialysis tasks : a stepped wedge cluster randomised controlled trial. PLoS ONE, 16(7). View this article in WRRO
- A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI. Human Reproduction, 36(7), 1841-1853. View this article in WRRO
- Bridging the age gap in breast cancer: cluster randomized trial of the effects of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices. British Journal of Surgery, 108(5), 499-510. View this article in WRRO
- Improving outcomes for women aged 70 years or above with early breast cancer: research programme including a cluster RCT. Programme Grants for Applied Research, 10(6), 1-114.
All publications
Books
- Medical Statistics: A Textbook for the Health Sciences, 5th Edition. Wiley-Blackwell.
- How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research. John Wiley & Sons Ltd..
- Quality of Life Outcomes in Clinical Trials and Health-Care Evaluation. Wiley-Blackwell.
- How to Display Data. Wiley-Blackwell.
- Medical Statistics: A Textbook for the Health Sciences. Wiley-Blackwell.
Journal articles
- A retrospective analysis of conditional power assumptions in clinical trials with continuous or binary endpoints. Trials, 24.
- Risk factors associated with multimorbidity among children aged under-five years in Sub-Saharan African countries: a scoping review. International Journal of Environmental Research and Public Health, 20(2).
- Symptom burden according to dialysis day of the week in three times a week haemodialysis patients. PLOS ONE, 17(9).
- Varicose veins treatment in England: population-based study of time trends and disparities related to demographic, ethnic, socioeconomic, and geographical factors. BJS Open, 6(4).
- Individual, household and area predictors of anaemia among children aged 6–59 months in Nigeria. Public Health in Practice, 3. View this article in WRRO
- An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia : the Journeying through Dementia RCT. Health Technology Assessment, 26(24), 1-151.
- The Journeying through Dementia psychosocial intervention versus usual care study: a single-blind, parallel group, phase 3 trial. The Lancet Healthy Longevity, 3(4), e276-e285.
- Association of task-shared psychological interventions with depression outcomes in low- and middle-income countries : a systematic review and individual patient data meta-analysis. JAMA Psychiatry.
- NMR Spectroscopy of live human asthenozoospermic and normozoospermic sperm metabolism. Reproduction and Fertility.
- Recruitment, consent and retention of participants in randomised controlled trials : a review of trials published in the National Institute for Health Research (NIHR) Journals Library (1997–2020). BMJ Open, 12(2). View this article in WRRO
- Statistical analysis of publicly funded cluster randomised controlled trials : a review of the National Institute for Health Research Journals Library. Trials, 23(1). View this article in WRRO
- Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation : RCT and systematic review. Health Technology Assessment, 26(10), 1-211. View this article in WRRO
- Regarding the articles on home spirometry. Journal of Cystic Fibrosis. View this article in WRRO
- Patients’ expectations and experiences of accelerated access to physiotherapy for sciatica: qualitative findings from a mixed-methods study. Physiotherapy.
- Endometrial scratch in women undergoing first-time IVF treatment : a systematic review and meta-analysis of randomized controlled trials. Reproductive BioMedicine Online.
- The current role of induced endometrial trauma (endometrial scratch) in women undergoing infertility treatment. Seminars in Reproductive Medicine. View this article in WRRO
- Individual and contextual factors associated with malaria among children 6–59 months in Nigeria: a multilevel mixed effect logistic model approach. International Journal of Environmental Research and Public Health, 18(21). View this article in WRRO
- A qualitative exploration of patient experiences of medication for sciatica. Musculoskeletal Science and Practice, 55.
- An intervention to support adherence to inhaled medication in adults with cystic fibrosis : the ACtiF research programme including RCT. Programme Grants for Applied Research, 9(11), 1-146.
- Self-management intervention to reduce pulmonary exacerbations by supporting treatment adherence in adults with cystic fibrosis: a randomised controlled trial. Thorax. View this article in WRRO
- Comprehensive review of statistical methods for analysing patient-reported outcomes (PROs) used as primary outcomes in randomised controlled trials (RCTs) published by the UK’s Health Technology Assessment (HTA) journal (1997–2020). BMJ Open, 11(9). View this article in WRRO
- Feasibility and benefits of a structured prehabilitation programme prior to Autologous Stem Cell Transplantation (ASCT) in patients with Myeloma; A prospective feasibility study. Physiotherapy.
- A breakthrough series collaborative to increase patient participation with hemodialysis tasks : a stepped wedge cluster randomised controlled trial. PLoS ONE, 16(7). View this article in WRRO
- Process evaluation of the Bridging the Age Gap in Breast Cancer decision support intervention cluster randomised trial. Trials, 22(1). View this article in WRRO
- A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI. Human Reproduction, 36(7), 1841-1853. View this article in WRRO
- Observational cohort study in older women with early breast cancer: use of radiation therapy and impact on health-related quality of life and mortality. Radiotherapy and Oncology.
- Estimating the minimum important difference in the DEMQOL instrument in people with dementia. Quality of Life Research, 30(10), 2995-3005.
- Bridging The Age Gap: observational cohort study of effects of chemotherapy and trastuzumab on recurrence, survival and quality of life in older women with early breast cancer.. Br J Cancer.
- Volume–outcome relationships in open and endovascular repair of abdominal aortic aneurysm: administrative data 2006–2018. British Journal of Surgery, 108(5), 521-527. View this article in WRRO
- Cost-effectiveness modeling of surgery plus adjuvant endocrine therapy versus primary endocrine therapy alone in UK women aged 70 and over with early breast cancer. Value in Health. View this article in WRRO
- Bridging the age gap in breast cancer: cluster randomized trial of the effects of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices. British Journal of Surgery, 108(5), 499-510. View this article in WRRO
- Bridging the Age Gap in breast cancer: Impact of chemotherapy on quality of life in older women with early breast cancer. European Journal of Cancer, 144, 269-280.
- Bridging the age gap in breast cancer. Impacts of omission of breast cancer surgery in older women with oestrogen receptor positive early breast cancer. A risk stratified analysis of survival outcomes and quality of life. European Journal of Cancer, 142, 48-62.
- Treatment choices for older women with primary operable breast cancer and cognitive impairment: Results from a prospective, multicentre cohort study.. J Geriatr Oncol.
- A systematic review of the “promising zone” design. Trials, 21(1).
- A scoping review of the risk factors associated with anaemia among children under five years in sub-Saharan African countries. International Journal of Environmental Research and Public Health, 17(23).
- Risk factors associated with malnutrition among children under-five years in Sub-Saharan African countries : a scoping review. International Journal of Environmental Research and Public Health, 17(23).
- Variation in the rates of surgical treatment of older women with operable breast cancer between UK breast units: Analysis of the Bridging the Age Gap Study. European Journal of Cancer, 138, S29-S29.
- Quality of life outcomes following breast surgery in older women with operable breast cancer: Analysis of the Bridging the Age Gap study. European Journal of Cancer, 138, S29-S30.
- Impacts of omission of breast cancer surgery in older women with ER+ early breast cancer. A risk stratified analysis of survival and quality of life outcomes. European Journal of Cancer, 138, S6-S7.
- Cluster randomised trial to evaluate the clinical benefits of decision support interventions for older women with operable breast cancer. European Journal of Cancer, 138, S7-S7.
- Feasibility study for supporting medication adherence for adults with cystic fibrosis: mixed-methods process evaluation. BMJ Open, 10(10), e039089-e039089.
- Age specific recruitment and retention to a large multicentre observational breast cancer trial in older women: The Age Gap Trial. Journal of Geriatric Oncology.
- A randomised, controlled pilot study of cognitive analytic therapy (CAT) for stressed pregnant women with underlying anxiety and depression in a routine health service setting. Clinical Psychology & Psychotherapy.
- Frailty state utility and minimally important difference: findings from the North West Adelaide Health Study. Age and Ageing.
- Observational cohort study to determine the degree and causes of variation in the rate of surgery or primary endocrine therapy in older women with operable breast cancer. European Journal of Surgical Oncology.
- Breast cancer surgery in older women: outcomes of the Bridging Age Gap in Breast Cancer study. British Journal of Surgery. View this article in WRRO
- A review of public health economic modelling in the National Institute for Health and Care Excellence (NICE). HRB Open Research, 3. View this article in WRRO
- Electronic personal assessment questionnaire for vascular patients (ePAQ-VAS) development and validity. British Journal of Surgery. View this article in WRRO
- Challenges in the design, planning and implementation of trials evaluating group interventions. Trials, 21. View this article in WRRO
- Correction to: Sample size estimation for randomised controlled trials with repeated assessment of patient-reported outcomes: what correlation between baseline and follow-up outcomes should we assume?. Trials, 20(1).
- Correction to: Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial – the development of the DELTA2 guidance. Trials, 20(1).
- Exploring the implications of different approaches to estimate centre-level adherence using objective adherence data in an adult cystic fibrosis centre - a retrospective observational study. Journal of Cystic Fibrosis. View this article in WRRO
- Practical help for specifying the target difference in sample size calculations for RCTs : the DELTA2 five-stage study, including a workshop. Health Technology Assessment, 23(60), 1-88. View this article in WRRO
- Sample size estimation for randomised controlled trials with repeated assessment of patient-reported outcomes : what correlation between baseline and follow-up outcomes should we assume?. Trials, 20(1). View this article in WRRO
- Study protocol for a randomised controlled trial assessing the clinical and cost-effectiveness of the Journeying through Dementia (JtD) intervention compared to usual care. BMJ Open, 9(9). View this article in WRRO
- Behavioural activation therapy for post-stroke depression : the BEADS feasibility RCT. Health Technology Assessment, 23(47), 1-176. View this article in WRRO
- Cost-effectiveness of offering an area-level financial incentive on breast feeding : a within-cluster randomised controlled trial analysis. Archives of Disease in Childhood. View this article in WRRO
- Intravenous antibiotic use and exacerbation events in an adult cystic fibrosis centre: A prospective observational study. Respiratory Medicine. View this article in WRRO
- Cost-effectiveness of PoNDER health visitor training for mothers at lower risk of depression: findings on prevention of postnatal depression from a cluster-randomised controlled trial. Psychological Medicine, 49(08), 1324-1334. View this article in WRRO
- Supporting medication adherence for adults with cystic fibrosis: a randomised feasibility study. BMC Pulmonary Medicine, 19. View this article in WRRO
- Quality of life versus Length of Life Considerations in Cancer Patients: A Systematic Literature Review. Psycho-Oncology. View this article in WRRO
- A role for MCDA to navigate the trade-offs in the National Institute for Health and Care Excellence’s public health recommendations. Operations Research for Health Care. View this article in WRRO
- A pragmatic behavior-based habit index for adherence to nebulized treatments among adults with cystic fibrosis. Patient Preference and Adherence, 2019(13), 283-294. View this article in WRRO
- Understanding FEV1 for the purpose of cystic fibrosis registry comparisons: Does bias in annual review FEV1 affect between-centre comparison within the UK? An analysis of registry data. Journal of Evaluation in Clinical Practice. View this article in WRRO
- Probing human sperm metabolism using 13C-magnetic resonance spectroscopy.. Molecular Human Reproduction, 25(1), 30-41. View this article in WRRO
- Symptoms at lung cancer diagnosis are associated with major differences in prognosis.. Thorax, 73(12), 1177-1181. View this article in WRRO
- DELTA² guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. BMJ (Online), 363. View this article in WRRO
- Sex differences in national rates of repair of emergency abdominal aortic aneurysm. British Journal of Surgery. View this article in WRRO
- DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. Trials, 19. View this article in WRRO
- Appropriate statistical methods for analysing partially nested randomised controlled trials with continuous outcomes: a simulation study.. BMC Medical Research Methodology, 18(1), 105-105. View this article in WRRO
- Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance.. Trials, 19(542). View this article in WRRO
- Introduction of a novel magnetic resonance imaging-based scoring system for assessing disease activity in children with juvenile dermatomyositis. Rheumatology, 57(9), 1661-1668. View this article in WRRO
- The importance of data issues when comparing cystic fibrosis registry outcomes between countries: Are annual review FEV1 in the UK only collected when subjects are well?. Journal of Evaluation in Clinical Practice, 24(4), 745-751. View this article in WRRO
- Does early intervention improve outcomes in the physiotherapy management of lumbar radicular syndrome? Results of the POLAR pilot randomised controlled trial. BMJ Open, 8(7), e021631-e021631. View this article in WRRO
- Role of habit in treatment adherence among adults with cystic fibrosis. Thorax. View this article in WRRO
- A prospective longitudinal study of Pasireotide in Nelson’s syndrome. Pituitary, 21(3), 247-255. View this article in WRRO
- Induced endometrial trauma (endometrial scratch) in the mid-luteal menstrual cycle phase preceding first cycle IVF/ICSI versus usual IVF/ICSI therapy: study protocol for a randomised controlled trial.. BMJ Open, 8(5). View this article in WRRO
- FP654SYMPTOM BURDEN ACCORDING TO DIALYSIS DAY OF THE WEEK IN THREE TIMES A WEEK HEMODIALYSIS PATIENTS. Nephrology Dialysis Transplantation, 33(suppl_1), i265-i265.
- Do cystic fibrosis centres with the lowest FEV1 still use the least amount of intravenous antibiotics? A registry-based comparison of intravenous antibiotic use among adult CF centres in the UK. Journal of Cystic Fibrosis, 17(3), 360-367. View this article in WRRO
- Are pilot trials useful for predicting randomisation and attrition rates in definitive studies: A review of publicly funded trials. Clinical Trials, 15(2), 189-196. View this article in WRRO
- Is it feasible to conduct a randomised controlled trial of pretransplant exercise (prehabilitation) for patients with multiple myeloma awaiting autologous haematopoietic stem cell transplantation? Protocol for the PREeMPT study. BMJ Open, 8. View this article in WRRO
- Effect of Financial Incentives on Breastfeeding: A Cluster Randomized Clinical Trial.. JAMA Pediatrics, 172(2), ---.
- Rationale and design for SHAREHD: a quality improvement collaborative to scale up Shared Haemodialysis Care for patients on centre based haemodialysis. BMC Nephrology, 18(1). View this article in WRRO
- The Relationship between Hospital or Surgeon Volume and Outcomes in Lower Limb Vascular Surgery in the United Kingdom and Europe. Annals of Vascular Surgery, 45, 271-286. View this article in WRRO
- Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity. BMC Medical Research Methodology, 17(1). View this article in WRRO
- Rescue therapy within the UK Cystic Fibrosis Registry: An exploration of predictors of intravenous antibiotic use amongst adults with CF. Respirology. View this article in WRRO
- Systematic review of carotid artery procedures and the volume–outcome relationship in Europe. British Journal of Surgery, 104(10), 1273-1283. View this article in WRRO
- Bridging the age gap in breast cancer: evaluation of decision support interventions for older women with operable breast cancer: protocol for a cluster randomised controlled trial. BMJ Open, 7(7). View this article in WRRO
- A preventative lifestyle intervention for older adults (lifestyle matters): a randomised controlled trial. Age And Ageing, 46(4), 627-634. View this article in WRRO
- I mpact of P elvic Floor Muscle Training on S exual function of women with U rinary Incontinence and a comparison of electrical stimulation versus standard treatment (IPSU Trial): a randomised controlled trial. Physiotherapy. View this article in WRRO
- Choosing the target difference ('effect size') for a randomised controlled trial - DELTA2 guidance protocol. Trials, 18. View this article in WRRO
- Diagnostic accuracy of DXA compared to conventional spine radiographs for the detection of vertebral fractures in children. European Radiology, 27(5), 2188-2199. View this article in WRRO
- A programme to spread eGFR graph surveillance for the early identification, support and treatment of people with progressive chronic kidney disease (ASSIST-CKD): protocol for the stepped wedge implementation and evaluation of an intervention to reduce late presentation for renal replacement therapy.. BMC Nephrology, 18. View this article in WRRO
- Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol. BMJ OPEN, 7(3). View this article in WRRO
- What influences healthcare professionals' treatment preferences for older women with operable breast cancer? An application of the discrete choice experiment. European Journal of Surgical Oncology (EJSO), 43(7), 1282-1287. View this article in WRRO
- Procedure Volume and the Association with Short-term Mortality Following Abdominal Aortic Aneurysm Repair in European Populations: A Systematic Review. European Journal of Vascular and Endovascular Surgery, 53(1), 77-88. View this article in WRRO
- Recommendations for the analysis of individually randomised controlled trials with clustering in one arm – a case of continuous outcomes. BMC Medical Research Methodology, 16. View this article in WRRO
- Using MCDA to generate and interpret evidence to inform local government investment in public health. EURO Journal on Decision Processes, 4(3), 161-181. View this article in WRRO
- Behavioural Activation Therapy for Depression after Stroke (BEADS): a study protocol for a feasibility randomised controlled pilot trial of a psychological intervention for post-stroke depression. Pilot and Feasibility Studies, 2(1). View this article in WRRO
- A self-managed single exercise programme versus usual physiotherapy treatment for rotator cuff tendinopathy: a randomised controlled trial (the SELF study). Clinical Rehabilitation, 30(7), 686-696. View this article in WRRO
- Accurate reporting of adherence to inhaled therapies in adults with cystic fibrosis: methods to calculate normative adherence. Patient Preference and Adherence, 10, 887-900. View this article in WRRO
- Cluster randomised controlled trial of a financial incentive for mothers to improve breast feeding in areas with low breastfeeding rates: the NOSH study protocol. BMJ Open, 6. View this article in WRRO
- Diagnosis of vertebral fractures in children: is a simplified algorithm-based qualitative technique reliable?. Pediatric Radiology, 46(5), 680-688. View this article in WRRO
- The relationship between hospital or surgeon volume and outcomes in lower limb vascular surgery in Europe. HTAi 2016 Abstract Book (ISUU), 131-`32.
- Understanding the barriers and enablers to implementation of a self-managed exercise intervention: a qualitative study. Physiotherapy, 101(3), 279-285. View this article in WRRO
- Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study. The Lancet Neurology, 14(7), 702-709. View this article in WRRO
- A rapid review indicated higher recruitment rates in treatment trials than in prevention trials. Journal of Clinical Epidemiology, 68(3), 347-354. View this article in WRRO
- Consumer views on a new holistic screening tool for supportive and palliative-care needs: Sheffield Profile for Assessment and Referral for Care (SPARC): a survey of self-help support groups in health care.. Health Expect, 18(4), 562-577.
- Putting Life in Years (PLINY): a pilot randomised controlled trial and mixed-methods process evaluation of telephone friendship groups for community living older adults. Public Health Research, 2(7).
- Prioritising public health guidance topics in the National Institute for Health and Care Excellence using the Analytic Hierarchy Process. Public Health, 128(10), 896-903. View this article in WRRO
- Estimating effect sizes for health-related quality of life outcomes.. Stat Methods Med Res, 23(5), 430-439.
- 57 Self-managed Loaded Exercise Versus Usual Physiotherapy Treatment For Rotator Cuff Tendinopathy: A Randomised Controlled Trial (the Self Study). British Journal of Sports Medicine, 48(Suppl 2), A37.1-A37.
- Sample size requirements to estimate key design parameters from external pilot randomised controlled trials: a simulation study. Trials, 15(1), 264-264. View this article in WRRO
- Mapping EQ-5D Utility Scores from the PedsQL™ Generic Core Scales. PharmacoEconomics.
- PLD.26 The ECCLIPPx study: Electrical Impedance Prediction of Preterm Birth.. Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A113-A116.
- 'Putting Life in Years' (PLINY) telephone friendship groups research study: Pilot randomised controlled trial. Trials, 15(1). View this article in WRRO
- Quality of life in children and adolescents with Osteogenesis Imperfecta: a qualitative interview based study.. Health Qual Life Outcomes, 12, 54. View this article in WRRO
- Patients with rotator cuff tendinopathy can successfully self-manage, but with certain caveats: A qualitative study. Physiotherapy (United Kingdom), 100(1), 80-85. View this article in WRRO
- A comparison of psychological stress among women with and without reproductive failure. International Journal of Gynecology and Obstetrics, 124(2), 143-147.
- Self-managed loaded exercise versus usual physiotherapy treatment for rotator cuff tendinopathy: a pilot randomised controlled trial.. Physiotherapy, 100(1), 54-60. View this article in WRRO
- A randomised controlled trial and cost-effectiveness evaluation of 'booster' interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods.. Health Technol Assess, 18(13), 1-210.
- The impact on the family carer of motor neurone disease and intervention with noninvasive ventilation.. J Palliat Med, 16(12), 1602-1609.
- Epidemiology of Rotator Cuff Tendinopathy: A Systematic Review. Shoulder & Elbow, 5(4), 256-265.
- Developing a disease specific quality of life measure for children with Osteogenesis Imperfecta. QUALITY OF LIFE RESEARCH, 22.
- Use of non-invasive ventilation at end of life.. Palliat Med, 27(9), 878.
- The effectiveness of salicylic acid plasters compared with 'usual' scalpel debridement of corns: a randomised controlled trial.. J Foot Ankle Res, 6(1), 40. View this article in WRRO
- Lifestyle Matters for maintenance of health and wellbeing in people aged 65 years and over: study protocol for a randomised controlled trial.. Trials, 14, 302. View this article in WRRO
- The central nervous system--an additional consideration in 'rotator cuff tendinopathy' and a potential basis for understanding response to loaded therapeutic exercise.. Man Ther, 18(6), 468-472. View this article in WRRO
- A Review of Systematic Reviews of the Effectiveness of Conservative Interventions for Rotator Cuff Tendinopathy. Shoulder & Elbow, 5(3), 151-167.
- Developing the SELF study: A focus group with patients and the public. International Journal of Therapy and Rehabilitation, 20(4), 200-206.
- The use of non-invasive ventilation at end of life in patients with motor neurone disease: a qualitative exploration of family carer and health professional experiences.. Palliat Med, 27(6), 516-523. View this article in WRRO
- Development of a self-managed loaded exercise programme for rotator cuff tendinopathy.. Physiotherapy, 99(4), 358-362. View this article in WRRO
- Dynamic pelvic floor ultrasound for lower urinary tract symptoms in children--initial report on normative values.. J Pediatr Urol, 9(6 Pt A), 950-954.
- Sample size requirements for pilot randomised controlled trials with continuous outcomes: a simulation study. Trials, 14(Suppl 1), P46-P46.
- Sample size requirements for pilot randomised controlled trials with binary outcomes: a simulation study. Trials, 14(Suppl 1), O21-O21.
- Recommendations for managing missing data, attrition and response shift in palliative and end-of-life care research: Part of the MORECare research method guidance on statistical issues. Palliative Medicine, 27(10), 899-907.
- Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72.. J Neurol Neurosurg Psychiatry, 84(1), 79-87.
- The initiation of non-invasive ventilation for patients with motor neuron disease: patient and carer perceptions of obstacles and outcomes.. Amyotroph Lateral Scler Frontotemporal Degener, 14(2), 105-110.
- The natural history of motor neuron disease: assessing the impact of specialist care.. Amyotroph Lateral Scler Frontotemporal Degener, 14(1), 13-19.
- A before and after study assessing the impact of a new model for recognizing and responding to early signs of deterioration in an acute hospital.. J Adv Nurs, 69(1), 41-52.
- Observational prospective cohort study of patients with newly-diagnosed ocular sebaceous carcinoma. British Journal of Ophthalmology.
- ARE VIDEOS VALUABLE IN COUPLES RELATIONSHIP THERAPY?. JOURNAL OF SEXUAL MEDICINE, 9, 275-275.
- A mixed methods study to evaluate the clinical and cost-effectiveness of a self-managed exercise programme versus usual physiotherapy for chronic rotator cuff disorders: protocol for the SELF study.. BMC Musculoskelet Disord, 13, 62. View this article in WRRO
- Analyzing time to event outcomes with a Cox regression model. Wiley Interdisciplinary Reviews: Computational Statistics.
- Early diagnosis of lung cancer: Evaluation of a community-based social marketing intervention. Thorax, 67(5), 412-417.
- Delphi research: issues raised by a pilot study.. Nurse Res, 19(2), 37-44.
- An evaluation of patient-reported outcome measures in lower limb reconstruction surgery. Quality of Life Research, 21(10), 1731-1743.
- A comparison of the discriminative and evaluative properties of the SF-36 and the SF-6D index. Quality of Life Research, 1-10.
- Letter by Blackburn et al regarding article, "Is the Montreal cognitive assessment superior to the mini-mental state examination to detect poststroke cognitive impairment? A study with neuropsychological evaluation".. Stroke, 42(11), e582.
- THE HEALTH OF POSTNATAL WOMEN'S PARTNERS UP TO 18 MONTHS AFTER THEIR BABY WAS BORN: A LONGITUDINAL SURVEY ALONGSIDE A RANDOMISED CONTROLLED TRIAL. J EPIDEMIOL COMMUN H, 65.
- Universal prevention of depression in women postnatally: cluster randomized trial evidence in primary care. PSYCHOL MED, 41(4), 739-748. View this article in WRRO
- "Booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods: internal pilot and feasibility study.. BMC Public Health, 11, 129. View this article in WRRO
- Analysing data from a cluster randomized trial (cRCT) in primary care: a case study. JOURNAL OF APPLIED STATISTICS, 38(10), 2253-2269.
- Early diagnosis of lung cancer: Evaluation of a community-based social marketing intervention. Thorax.
- Dorsal cortical comminution as a predictor of redisplacement of distal radius fractures in children. Injury, 42(2), 173-177.
- Dorsal cortical comminution as a predictor of redisplacement of distal radius fractures in children.. Injury, 42(2), 173-177.
- Assessing the impact older people from care homes place on the emergency services.. Eur J Emerg Med, 18(2), 81-85.
- Dorsal cortical comminution as a predictor of re-displacement of distal radius fractures in children. Injury Extra, 41(12), 191-191.
- Assessing quality of care from hospital case notes: comparison of reliability of two methods.. Qual Saf Health Care, 19(6), e2.
- The views of older women towards mammographic screening: a qualitative and quantitative study.. Br J Cancer, 102(10), 1461-1467. View this article in WRRO
- Therapist effects in randomised controlled trials: what to do about them. J CLIN NURS, 19(7-8), 1102-1112.
- Quality of life, self-esteem, fatigue, and sexual function in young men after cancer: a controlled cross-sectional study.. Cancer, 116(6), 1592-1601.
- A randomised 2 X 2 trial of community versus hospital pulmonary rehabilitation for chronic obstructive pulmonary disease followed by telephone or conventional follow-up. HEALTH TECHNOL ASSES, 14(6), 1-+.
- Comparison of case note review methods for evaluating quality and safety in health care. HEALTH TECHNOL ASSES, 14(10), 1-+. View this article in WRRO
- Physical activity, quality of life, weight status and diet in adolescents. Quality of Life Research, 19(7), 943-954. View this article in WRRO
- Health care professionals' preferences for extending mammographic breast screening to the over 70s. Journal of Geriatric Oncology.
- Universal prevention of depression in women postnatally: cluster randomized trial evidence in primary care. Psychological Medicine, 1-10.
- A randomised 2 x 2 trial of community versus hospital pulmonary rehabilitation, followed by telephone or conventional follow-up.. Health technology assessment (Winchester, England), 14(6).
- A randomised controlled trial and cost-effectiveness evaluation of "booster" interventions to sustain increases in physical activity in middle-aged adults in deprived urban neighbourhoods.. BMC Public Health, 10, 3. View this article in WRRO
- Extension of mammographic screening to the over 70s: a study of patient and health care professional opinion. European Journal of Surgical Oncology (EJSO), 35(11), 1236-1236.
- Immediate and delayed add-back hormonal replacement therapy during ultra long GnRH agonist treatment of chronic cyclical pelvic pain.. BJOG, 116(12), 1646-1656.
- Follow-up care for cancer survivors: the views of clinicians.. Br J Cancer, 101(4), 568-574. View this article in WRRO
- Follow-up care for cancer survivors: views of the younger adult.. Br J Cancer, 101(4), 561-567. View this article in WRRO
- Health and use of health services: a comparison between Gypsies and Travellers and other ethnic groups.. Ethn Health, 14(4), 359-377.
- Impact of a mental health teaching programme on adolescents.. Br J Psychiatry, 194(4), 365-370.
- Consultants' forum: should post hoc sample size calculations be done?. Pharm Stat, 8(2), 163-169.
- Psychological interventions for postnatal depression: cluster randomised trial and economic evaluation. The PoNDER trial. HEALTH TECHNOL ASSES, 13(30), 1-+.
- Clinical audit of core podiatry treatment in the NHS.. J Foot Ankle Res, 2, 7. View this article in WRRO
- Clinical effectiveness of health visitor training in psychologically informed approaches for depression in postnatal women: pragmatic cluster randomised trial in primary care.. BMJ, 338, a3045. View this article in WRRO
- The views of older women (>70 years) towards mammographic screening: A qualitative study. European Journal of Surgical Oncology (EJSO), 34(10), 1197-1197.
- Can emergency medical service staff predict the disposition of patients they are transporting?. Emerg Med J, 25(10), 691-694.
- A pilot survey of socio-economic differences in child-feeding behaviours among parents of primary-school children.. Public Health Nutr, 11(10), 1030-1036.
- Changing trends in the decision-making preferences of women with early breast cancer.. Br J Surg, 95(3), 312-318.
- Physical activity among adolescents and barriers to delivering physical education in Cornwall and Lancashire, UK: a qualitative study of heads of PE and heads of schools.. BMC Public Health, 8, 273. View this article in WRRO
- Prevalence and consequences of androgen deficiency in young male cancer survivors in a controlled cross-sectional study.. J Clin Endocrinol Metab, 92(9), 3476-3482.
- Health-status of adult survivors of childhood cancer: A large-scale population-based study from the British Childhood Cancer Survivor Study. INT J CANCER, 121(3), 633-640.
- Predicting where future means will lie based on the results of the current trial.. Contemp Clin Trials, 28(4), 352-357.
- What influences clinicians' operative preferences for women with breast cancer? An application of the discrete choice experiment.. Eur J Cancer, 43(11), 1662-1669.
- Ineffectiveness of rosiglitazone therapy in Nelson's syndrome.. J Clin Endocrinol Metab, 92(5), 1758-1763.
- IO2-6 The Ponder Trial : A Cost-effectiveness Trial of Psychological Intervention by Health Visitors for Postnatal Depression(ISPOG2007). 女性心身医学, 12(1-2), 139.
- Consumer views on a new screening tool for supportive care needs: A survey of user groups representing a range of diagnoses. PSYCHO-ONCOL, 16(3), 271-272.
- Health status of Gypsies and Travellers in England.. J Epidemiol Community Health, 61(3), 198-204.
- Forefoot reconstruction: Effectiveness of Stainsby operation in treating disclocated lesser toes. Foot, 17(3), 136-142.
- Effect of psychological interventions on depressive symptoms in postnatal women - a cluster randomised trial in primary care. J REPROD INFANT PSYC, 25(3), 239-239.
- Telemedicine in dermatology: a randomised controlled trial.. Health Technol Assess, 10(43), iii-39.
- Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain.. BMJ, 333(7569), 623.
- A randomised controlled trial of acupuncture care for persistent low back pain: cost effectiveness analysis. BMJ, 333(7569), 626-626.
- Short-term follow-up of ceramic press fit first metatarso-phalangeal joint arthroplasty. The Foot, 16(3), 142-144.
- A randomized, double-blind, placebo-controlled trial of nutritional supplementation during acute illness.. Am J Med, 119(8), 693-699.
- A comparison between portable ultrasound (MIDUS) and nocturnal RigiScan when confirming the diagnosis of vascular organic erectile disorder.. Int J Impot Res, 18(4), 354-358.
- Cost-effectiveness (C-E) of tegaserod vs. placebo for treatment of irritable bowel syndrome with constipation (IBS-C). VALUE HEALTH, 9(3), A45-A45.
- Quality of life and cost-effectiveness of interferon-alpha in malignant melanoma: results from randomised trial.. Br J Cancer, 94(4), 492-498. View this article in WRRO
- Economic evaluation of MR cholangiopancreatography compared to diagnostic ERCP for the investigation of biliary tree obstruction. International Journal of Surgery, 4(1), 12-19.
- Telemedicine in dermatology: a randomised controlled trial.. Health technology assessment (Winchester, England), 10(43).
- MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review.. BMC Med Imaging, 6, 9. View this article in WRRO
- Targets and moving goal posts: changes in waiting times in a UK emergency department.. Emerg Med J, 22(10), 710-714.
- Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain.. Health technology assessment (Winchester, England), 9(32).
- Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain.. Health Technol Assess, 9(32), iii-109.
- Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D.. Qual Life Res, 14(6), 1523-1532.
- The use of bootstrap methods for estimating sample size and analysing health-related quality of life outcomes.. Stat Med, 24(7), 1075-1102.
- Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies.. Health technology assessment (Winchester, England), 9(9).
- Case-mix fails to explain variation in mastectomy rates: management of screen-detected breast cancer in a UK region 1997-2003.. Br J Cancer, 92(1), 55-59. View this article in WRRO
- Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies.. Health Technol Assess, 9(9), 1-iv. View this article in WRRO
- Longer term clinical and economic benefits of offering acupuncture care to patients with chronic low back pain.. Health technology assessment (Winchester, England), 9(32).
- Costs and effectiveness of pre- and post-operative home physiotherapy for total knee replacement: randomized controlled trial.. J Eval Clin Pract, 11(3), 283-292.
- Is Rigiscan or Portable Ultrasound the Investigation of Choice in Confirming Suspected Organic Erectile Disorder?. J SEX MED, 1, 71-71.
- Health-related quality of life in Huntington's disease: A comparison of two generic instruments, SF-36 and SIP. MOVEMENT DISORD, 19(11), 1341-1348.
- Patient reports of adverse events associated with acupuncture treatment: a prospective national survey. QUAL SAF HEALTH CARE, 13(5), 349-355.
- Do different types of nurses give different triage decisions in NHS Direct? A mixed methods study.. J Health Serv Res Policy, 9(4), 226-233.
- Bronchial auscultation: An effective adjunct to speech and language therapy bedside assessment when detecting dysphagia and aspiration?. Dysphagia, 19(4), 211-218.
- Sample size and power estimation for studies with health related quality of life outcomes: a comparison of four methods using the SF-36.. Health Qual Life Outcomes, 2, 26. View this article in WRRO
- Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients.. Transpl Int, 17(4), 182-187.
- Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients. Transplant International, 17(4), 182-187.
- Variation in cadaveric organ donor rates in the UK.. Nephrol Dial Transplant, 19(4), 963-968.
- A systematic review and economic evaluation of magnetic resonance cholangiopancreatography compared with diagnostic endoscopic retrograde cholangiopancreatography.. Health Technol Assess, 8(10), iii-89.
- Referral letters to colorectal surgeons: the impact of peer-mediated feedback.. Br J Gen Pract, 54(499), 123-126.
- Bronchial auscultation: An effective adjunct to speech and language therapy bedside assessment when detecting dysphagia and aspiration?. DYSPHAGIA, 19(4), 211-218.
- General practitioners' perceptions of asynchronous telemedicine in a randomized controlled trial of teledermatology.. J Telemed Telecare, 10(2), 94-98.
- Patient satisfaction with teledermatology: quantitative and qualitative results from a randomized controlled trial.. J Telemed Telecare, 10(1), 29-33.
- A systematic review and economic evaluation of magnetic resonance cholangiopancreatography compared with diagnostic endoscopic retrograde cholangiopancreatography.. Health technology assessment (Winchester, England), 8(10). View this article in WRRO
- The use of bootstrap methods for analysing Health-Related Quality of Life outcomes (particularly the SF-36).. Health Qual Life Outcomes, 2, 70. View this article in WRRO
- A randomized placebo-controlled trial of pre-treatment and short- or long-term maintenance therapy with amiodarone supporting DC cardioversion for persistent atrial fibrillation.. Eur Heart J, 25(2), 144-150.
- Continuing inequality: gender and social class influences on self perceived health after a heart attack.. J Epidemiol Community Health, 57(8), 622-627.
- Patients with chronic pain and abnormal pituitary function require investigation.. Lancet, 361(9376), 2203-2204.
- The potential benefit of vacuum devices augmenting psychosexual therapy for erectile dysfunction: A randomized controlled trial. Journal of Sex and Marital Therapy, 29(3), 227-236.
- Sample sizes for the SF-6D preference based measure of health from the SF-36: A comparison of two methods. Health Services and Outcomes Research Methodology, 4(1), 35-47.
- What is the relationship between the minimally important difference and health state utility values? The case of the SF-6D.. Health Qual Life Outcomes, 1, 4. View this article in WRRO
- Economic implications of the use of basiliximab in addition to triple immunosuppressive therapy in renal allograft recipients: a UK perspective.. Pharmacoeconomics, 21(2), 129-138.
- Risk-adjusted prognostic models for Hodgkin's disease (HD) and grade II non-Hodgkin's lymphoma (NHL II): validation on 6728 British National Lymphoma Investigation patients.. Br J Haematol, 120(2), 277-280.
- The economics of basiliximab (Simulect) in preventing acute rejection in renal transplantation.. Transpl Int, 15(9-10), 486-493.
- Update on the use of osteoarthritis-specific outcome measures.. Expert Rev Pharmacoecon Outcomes Res, 2(4), 337-346.
- Women's perceptions of informed choice in maternity care.. Midwifery, 18(2), 136-144.
- Discussion: Does EBM offer the best opportunity yet for teaching medical statistics?. STAT MED, 21(7), 979-981.
- Use of evidence based leaflets to promote informed choice in maternity care: randomised controlled trial in everyday practice.. BMJ, 324(7338), 643.
- A review of ordinal regression models applied on health-related quality of life assessments.. Stat Methods Med Res, 11(1), 49-67.
- Prevalence of sexual dysfunction in three psychiatric outpatient settings: A drug misuse service, an alcohol misuse service and a general adult psychiatry clinic. Sexual and Relationship Therapy, 17(2), 149-160.
- Quality of referrals to gynaecologists: Towards consensus. Journal of Clinical Governance, 10(4), 177-181.
- Quality of information on referrals to colorectal surgeons: towards consensus.. Curr Med Res Opin, 18(2), 72-77.
- Health-related quality of life and cost impact of irritable bowel syndrome in a UK primary care setting.. Pharmacoeconomics, 20(7), 455-462.
- A Prospective Survey of Adverse Events and Treatment Reactions following 34,000 Consultations with Professional Acupuncturists. Acupuncture in Medicine, 19(2), 93-102.
- Does vibration offer any advantage over visual stimulation studies (VSS) in the assessment of erectile capacity?. Int J Impot Res, 13(6), 329-337.
- Prognostic markers in malignant lymphoma: an analysis of 1,198 patients treated at a single centre.. Int J Oncol, 19(6), 1203-1209.
- Pharmacoeconomic evaluation of Simulect prophylaxis in renal transplant recipients.. Transplant Proc, 33(7-8), 3187-3191.
- The York acupuncture safety study: prospective survey of 34 000 treatments by traditional acupuncturists. BRIT MED J, 323(7311), 486-487.
- The implications of contact with the mentor for preregistration nursing and midwifery students.. J Adv Nurs, 35(2), 151-160.
- Using the SF-36 with older adults: a cross-sectional community-based survey.. Age Ageing, 30(4), 337-343. View this article in WRRO
- Methods for determining sample sizes for studies involving health-related quality of life measures: A tutorial. Health Services and Outcomes Research Methodology, 2(2), 83-99.
- Sexual difficulties within a group of patients with vulvodynia. Sexual and Relationship Therapy, 16(2), 113-126.
- Modeling long-term results of basiliximab (SIMULECT) use in patients after kidney transplantation in Great Britain. Przegla̧d lekarski, 58(2), 61-66.
- [Modeling long-term results of basiliximab (SIMULECT) use in patients after kidney transplantation in Great Britain].. Przegl Lek, 58(2), 61-66.
- UK, USA and Canada: how do their pressure ulcer prevalence and incidence data compare?. J Wound Care, 10(1), 530-535.
- Design and analysis of trials with quality of life as an outcome: a practical guide.. J Biopharm Stat, 11(3), 155-176.
- Costs and effectiveness of community postnatal support workers: randomised controlled trial.. BMJ, 321(7261), 593-598.
- High-dose growth hormone does not affect proinflammatory cytokine (tumor necrosis factor-alpha, interleukin-6, and interferon-gamma) release from activated peripheral blood mononuclear cells or after minimal to moderate surgical stress.. J Clin Endocrinol Metab, 85(9), 3383-3390.
- How effective are prevention strategies in reducing the prevalence of pressure ulcers?. J Wound Care, 9(6), 261-266.
- General practitioners' perceptions of store-and-forward teledermatology.. J Telemed Telecare, 6(1), 50-53.
- Costs and benefits of community postnatal support workers: a randomised controlled trial.. Health Technol Assess, 4(6), 1-100.
- Generic and condition-specific outcome measures for people with osteoarthritis of the knee.. Rheumatology (Oxford), 38(9), 870-877.
- Leptin binding activity changes with age: the link between leptin and puberty.. J Clin Endocrinol Metab, 84(7), 2336-2341.
- Measuring health-related quality of life in patients with venous leg ulcers.. Qual Life Res, 8(4), 327-336.
- The role of psychological and biological factors in postinfective gut dysfunction.. Gut, 44(3), 400-406.
- Testing headings for communicating the personal health record: Comparison from the recipients' perspective. Health Informatics Journal, 5(4), 179-187.
- The SF36 as an outcome measure of services for end stage renal failure.. Qual Health Care, 7(4), 209-221. View this article in WRRO
- Cost effectiveness of community leg ulcer clinics: randomised controlled trial.. BMJ, 316(7143), 1487-1491. View this article in WRRO
- Variations in venous leg ulcer care in the community. British Journal of Community Nursing, 3(1), 6-12.
- An evaluation of a nurse-led ear care service in primary care: benefits and costs.. Br J Gen Pract, 47(424), 699-703.
- Patients’ tolerance of leg ulcer treatments. British Journal of Community Health Nursing, 2(9), 427-435.
- Comparison of outcome measures for patients with chronic obstructive pulmonary disease (COPD) in an outpatient setting.. Thorax, 52(10), 879-887. View this article in WRRO
- Problems associated with patient satisfaction surveys. British Journal of Community Health Nursing, 2(3), 156-163.
- Psychometric scores and persistence of irritable bowel after infectious diarrhoea. Clinical Nutrition, 15(3), 143-143.
- Using the SF-36 and Euroqol on an elderly population.. Qual Life Res, 5(2), 195-204.
- Psychometric scores and persistence of irritable bowel after infectious diarrhoea.. Lancet, 347(8995), 150-153.
- A descriptive study of samples sizes used in agreement studies published in the PubMed repository. BMC Medical Research Methodology, 22(1).
- Improving outcomes for women aged 70 years or above with early breast cancer: research programme including a cluster RCT. Programme Grants for Applied Research, 10(6), 1-114.
- Bridging the age gap in breast cancer: impact of omission of breast cancer surgery in older women with oestrogen receptor-positive early breast cancer on quality-of-life outcomes. British Journal of Surgery.
- The feasibility of early pulmonary rehabilitation and activity after COPD exacerbations: external pilot randomised controlled trial, qualitative case study and exploratory economic evaluation. Health Technology Assessment, 22(11), 1-204. View this article in WRRO
- Carotid artery procedures and the volume-outcome relationship in Europe: a systematic review. British Journal of Surgery.
- Patient reports on adverse events associated with acupuncture: results of a prospective national survey. Focus on Alternative and Complementary Therapies, 8(4), 515-515.
- A Scoping Review of Selected Studies on Predictor Variables Associated with the Malaria Status among Children under Five Years in Sub-Saharan Africa. International Journal of Environmental Research and Public Health, 18(4), 2119-2119.
- Diagnostic accuracy of the magnetocardiograph for patients with suspected acute coronary syndrome. Emergency Medicine Journal.
- A machine-learning assisted review of the use of habit formation in medication adherence interventions for long-term conditions. Health Psychology Review.
Chapters
- Area Under the Curve (AUC), Encyclopedia of Quality of Life and Well-Being Research (pp. 219-221). Springer Netherlands
- The protocol, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 143-158).
- Simple analysis of cRCT outcomes using aggregate cluster-level summaries, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 83-101).
- Sample size: How many subjects/clusters do I need for my cluster randomised controlled trial?, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 50-82).
- Reporting of cRCTs, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 159-177).
- Regression methods of analysis for continuous outcomes using individual person-level data, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 102-125).
- Regression methods of analysis for binary, count and time-to-event outcomes for a cluster randomised controlled trial, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 126-142).
- Practical issues, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 178-194).
- How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research Preface, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. XIII-+).
- How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research Introduction, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 1-26).
- Design issues, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 27-49).
- Computing software, HOW TO DESIGN, ANALYSE AND REPORT CLUSTER RANDOMISED TRIALS IN MEDICINE AND HEALTH RELATED RESEARCH (pp. 195-233).
- Descriptive Analysis of Quantitative Data In Gerrish K & Lacey A (Ed.), The Research Process in Nursing (pp. 437-454). Wiley-Blackwell
Conference proceedings papers
- Endometrial scratching in women undergoing their first In Vitro Fertilisation (IVF) cycle: results from the UK Multicentre Endometrial Scratch Randomised Controlled Trial. HUMAN REPRODUCTION, Vol. 35 (pp 140-141)
- A randomised clinical feasibility trial of a breast immobilisation device:The SuPPORT 4 All Project.. RADIOTHERAPY AND ONCOLOGY, Vol. 152 (pp S78-S79)
- Bridging the age gap in breast cancer: optimisation of survival and quality of life outcomes in older women with early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, Vol. 180(2) (pp 594-594)
- Why is the early intervention development phase for complex health care interventions important? An overview of new guidance. Trials, Vol. 20(Supplement 1) (pp 99-99). Brighton, UK, 6 October 2019 - 9 October 2019.
- Sample estimation for randomised controlled trials with repeated assessment of quality of life: what correlation between baseline and follow up outcomes should we assume?. QUALITY OF LIFE RESEARCH, Vol. 27 (pp S34-S34)
- Comparison of statistical methods for the analysis of patient-reported outcomes in RCTS. QUALITY OF LIFE RESEARCH, Vol. 27 (pp S59-S60)
- Structured Light Plethysmography as a method of recording disease severity in Cystic Fibrosis. Respiratory function technologists/scient
- Is it feasible to conduct a randomised controlled trial of pre-habilitation in multiple myeloma (MM) patients awaiting autologous haematopoietic stem-cell transplantation (AHSCT)? The PREeMPT study. BONE MARROW TRANSPLANTATION, Vol. 53 (pp 343-344)
- Experiences of women and partners of women at increased familial breast cancer risk: A qualitative study of the impact upon partnerships. European Journal of Surgical Oncology, Vol. 44(6) (pp 904-905)
- Preference for quality of life versus length of life in older women making treatment decisions in early breast cancer. European Journal of Surgical Oncology, Vol. 44(6) (pp 871-871)
- Views and experiences of MRI breast screening in women at increased familial breast cancer risk. European Journal of Surgical Oncology, Vol. 44(6) (pp 905-906), 18 June 2018 - 19 June 2018. View this article in WRRO
- Comparison of quality of life of older women treated with surgery or primary endocrine therapy for early breast cancer: propensity score matched analysis of a large prospective multicentre cohort study. European Journal of Cancer, Vol. 92 (pp S3-S4)
- Comparison of quality of life of older women treated with surgery or primary endocrine therapy for early breast cancer: propensity score matched analysis of a large prospective multicentre cohort study. EUROPEAN JOURNAL OF CANCER, Vol. 92 (pp S3-S4)
- Quality of life of elderly women with early breast cancer following surgery. European Journal of Surgical Oncology, Vol. 44 (pp S4-S4)
- 1017. Quality of life of elderly women with early breast cancer following surgery. European Journal of Surgical Oncology, Vol. 43(11) (pp 2204-2205)
- Behavioural activation therapy for depression after stroke (BEADS): a feasibility randomised controlled pilot trial of a psychological intervention for post-stroke depression. INTERNATIONAL JOURNAL OF STROKE, Vol. 12 (pp 15-15)
- REAL WORLD EVIDENCE OF SUSTAINED IMPROVEMENT IN OBJECTIVE ADHERENCE TO MAINTENANCE INHALED THERAPIES IN AN ADULT CYSTIC FIBROSIS CENTRE. PEDIATRIC PULMONOLOGY, Vol. 52 (pp S488-S488) View this article in WRRO
- UNDERSTANDING FEV1 FOR THE PURPOSE OF CF REGISTRY COMPARISONS: ARE UK ANNUAL REVIEW FEV1 ONLY COLLECTED WHEN SUBJECTS ARE WELL?. PEDIATRIC PULMONOLOGY, Vol. 52 (pp S412-S412) View this article in WRRO
- UNDERSTANDING FEV1 FOR THE PURPOSE OF CF REGISTRY COMPARISONS: DOES BIAS IN ANNUAL REVIEW FEV1 AFFECT BETWEEN-CENTRE COMPARISON WITHIN THE UK?. PEDIATRIC PULMONOLOGY, Vol. 52 (pp S412-S413) View this article in WRRO
- EXPLORING DIFFERENT METHODS TO DISPLAY CENTRE-LEVEL DATA IN THE UK CF REGISTRY ANNUAL REPORT. PEDIATRIC PULMONOLOGY, Vol. 52 (pp S404-S404) View this article in WRRO
- 405 Use of clinical characteristics and pre-clinic data to optimise clinic use in adults with cystic fibrosis: development of consensus criteria using nominal group technique. Journal of Cystic Fibrosis, Vol. 16 (pp S165-S165)
- Estimating the underlying overall and centre recruitment rates in external pilot trials-how many centre-months of recruitment data do we need? A case study of the BEADS pilot trial. TRIALS, Vol. 18
- Development of an osteogenesis imperfecta (OI) specific quality of life measure (OIQoL). Physiotherapy, Vol. 102 (pp e10-e11)
- THE IMPORTANCE OF DATA COMPLETENESS IN DETERMINING CENTRE-LEVEL NEBULISER ADHERENCE RATES. PEDIATRIC PULMONOLOGY, Vol. 51 (pp 448-449) View this article in WRRO
- IMPROVING NEBULISER ADHERENCE IN AN ADULT CF CENTRE - DIFFERENCES IN UNADJUSTED ADHERENCE VS NORMATIVE ADHERENCE. PEDIATRIC PULMONOLOGY, Vol. 51 (pp 449-449) View this article in WRRO
- LONGITUDINAL MONITORING OF DISEASE PROGRESSION IN CHILDREN WITH MILD CF USING 3-HELIUM MRI AND LCI. Pediatric Pulmonology, Vol. 51 (pp 348-348)
- Analysis and reporting of trials which randomise couples to therapy based interventions: how should we do it?. Trials, Vol. 16(S2)
- Methodological, planning and implementation challenges for rcts evaluating group interventions. Trials, Vol. 14(Suppl 1) (pp O124-O124)
- A model to explain pain associated with rotator cuff tendinopathy and a rationale for response to therapeutic exercise. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 94(4) (pp A8-A8)
- Sample size determination through power simulation; practical lessons from a stepped wedge cluster randomised trial (SW CRT).. Trials, Vol. 12 Suppl 1 (pp A26)
- A COMPARISON OF THE DISCRIMINTATIVE AND EVALUATIVE PROPERTIES OF THE SF-36 AND THE SF-6D INDEX. VALUE HEALTH, Vol. 13(3) (pp A17-A17)
- The views of older women regarding mammographic screening: a qualitative and quantitative study. EJC SUPPLEMENTS, Vol. 8(3) (pp 242-242)
- EARLY DETECTION OF LUNG CANCER: A SOCIAL MARKETING EVALUATION. THORAX, Vol. 64 (pp A21-A21)
- Prevention of Postnatal Depression: Cost-Effectiveness of Health Visitor Training; Results from a Cluster Randomised Controlled Trial in Primary Care. J MENT HEALTH POLICY, Vol. 12 (pp S8-S8)
- The ponder trial: A cost-effectiveness trial of psychological intervention by health visitors for postnatal depression. J PSYCHOSOM OBST GYN, Vol. 28 (pp 64-64)
- Best buy for pulmonary rehabilitation: Comparison of community and hospital provision. A report of the cohort study of pulmonary rehabilitation. THORAX, Vol. 61 (pp II69-II69)
- Photo-dermoscopic screening in the management of suspected skin cancer. BRITISH JOURNAL OF DERMATOLOGY, Vol. 155 (pp 9-9)
- Health related quality of life in Huntington's disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol. 76
- Quality-adjusted survival and cost-effectiveness of transmyocardial revascularization using the CO2 laser. CIRCULATION, Vol. 111(20) (pp E319-E319)
- Quality of life in patients with autoimmune hepatitis measured with the SF-36 health status questionnaire. GUT, Vol. 53 (pp A84-A84)
- A randomized controlled trial of teledermatology. BRITISH JOURNAL OF DERMATOLOGY, Vol. 149 (pp 29-29)
Posters
- Challenges in the design, planning and implementation of trials evaluating group interventions. View this article in WRRO
- Methods to analyse partially nested randomised controlled trials.
- Analysis and reporting of individually randomised controlled trials with clustering in one arm only: how should we do it?.
Preprints
- Analysing cluster randomised controlled trials using MLE, GEE, GEE2 and QIF: results from four case studies, Research Square Platform LLC.
- Review of samples sizes used in agreement studies published in the PubMed database, Research Square.
- Individual and Contextual Factors Associated with Malaria among Children 6-59 Months in Nigeria: A Multilevel Mixed Effect Logistic Model Approach, MDPI AG.
- A Scoping Review of Selected Studies on Risk Factors Associated with the Malaria Status among Children Under-five Years in Sub-Sahara Africa, MDPI AG.
- Choosing the Target Difference (“effect size”) for a Randomised Controlled Trial - DELTA2 Guidance, MDPI AG.
- Medical Statistics: A Textbook for the Health Sciences, 5th Edition. Wiley-Blackwell.
- Research group
-
PhD Students
- Phillips Edomwonyi Obasohan
- Louisa Robinson
- Yirui Qian
- Bright Offorha
- Nikki Totton
- Grants
-
- FIRST: Prospective randomised controlled trial comparing three splints for finger flexor tendon repairs. Co-applicant. NIHR HTA Programme. (2022-2025). £1,151,006.
- MEErKAT: MEsenteric Excision and Kono-s Anastomosis Trial. Co-applicant. NIHR HTA Programme. (2021-2026). £1,657,876.
- SPACES: Supporting Physical and Activity through Co-production in people with Severe Mental Illness. Co-applicant. NIHR PGfAR Programme. (2021-2027). £2,525,160.
- BASIS: Bracing Adolescent Idiopathic ScoliosIS Study night-time versus full-time bracing in adolescent idiopathic scoliosis. Co-applicant. NIHR HTA Programme. (2021-2031). £2,457,724.
- HELP Infertility? (Hysteroscopic Excision of Leiomyoma and Polyp in Infertility): two randomised controlled trials. Co-applicant. NIHR HTA Programme. (2020-2028). £2,050,304.
- MATTS: Major trauma Triage Tool Study. Co-applicant. NIHR HTA Programme. (2018-2022). £1,211,034.
- STAR-MS: Autologous Stem Cell Transplantation versus Alemtuzumab in Relapsing Remitting MS. Co-applicant. NIHR EME Programme. (2019-2024) £2,348,027.
- Investigating socioeconomic and geographical disparities in vascular surgery rates and outcomes in England. Co-applicant. NIHR PGfAR Programme. (2020-2022) £145,049.
- NIHR Senior Investigator Award. Principal investigator. NIHR. (2018-2022) £60,000.
- Teaching interests
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I have developed several courses on teaching medical statistics to medical and health science students, clinicians and allied health professionals. I have also co-authored four textbooks: 'Medical Statistics: A Textbook for the Health Sciences 5th edition' 'Medical Statistics: A Textbook for the Health Sciences 4th edition; 'How to Display Data' and 'How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research'.
I co-ordinate and teach on HAR6035 'An Introduction to Statistics and Critical Appraisal' module on the Master of Public Health programme and contribute to the distance learning version (HAR6042).
- Professional activities and memberships
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- Independent statistician member on several data and safety monitoring committees
- Member of the NIHR Programme Grants for Applied Research Committee
- Member of the NIHR Pre-doctoral Fellowships Selection Committee
- Member of the Irish Health Research Board