Animal welfare breakthrough helps to accelerate brain and diabetes research

A pioneering breakthrough in the way animal research is conducted will help to accelerate studies of the brain.Zebrafish

A team of scientists from the University of Sheffield have developed a new method of studying neurovascular coupling – how the brain regulates its blood supply – using zebrafish.

The Sheffield team, led by Professor Tim Chico (Bateson Centre member), Dr Clare Howarth and PhD student Karishma Chhabria (Bateson Centre member), developed the ground breaking method using the 1-2mm long tadpole-like zebrafish larvae which are nearly transparent. Their transparency allows the observation of brain function and blood flow in a non-invasive and completely painless way.

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