3 October 2019

Disease Models and Mechanisms Cover Image

Congratulations to Karishma Chhabria whose image was chosen to feature on the front cover of Disease Models and Mechanisms.

Scientific image showing Dorsal view of a 9-day old zebrafish brain

A whole-mount immunostained brain of a 9-day-old zebrafish showing different cellular markers, acquired using a Zeiss Lightsheet fluorescent microscope. Glutamate receptors on neurons and glial cells are in green, phalloidin stain for actin fibers is in red, DAPI stain for nuclear localization is in cyan and the enzyme, glutamine synthetase, is in blue. Expression of these, particularly glutamine synthetase, is reduced under hyperglycemia, a prominent pathology of diabetes.

Read the full paper ‘Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behavior in zebrafish’, here: DMM (2019) 039867.

Contact us

The Bateson Centre
Firth Court
The University of Sheffield
Western Bank
Sheffield S10 2TN

bateson@sheffield.ac.uk

+44 114 222 2710

Flagship institutes

The University’s four flagship institutes bring together our key strengths to tackle global issues, turning interdisciplinary and translational research into real-world solutions.