Professor Anthony Weetman MD DSc FRCP FMedSci

Emeritus Professor of MedicineProfessor Tony Weetman

Faculty of Medicine, Dentistry and Health
University of Sheffield
Beech Hill Road
Sheffield
S10 2RX

Telephone: +44 (0)114 222 8712
Email: a.p.weetman@sheffield.ac.uk

Career History:

  • Sir Arthur Hall Professor of Medicine and Honorary Consultant Endocrinologist from 1991-2016
  • Dean of the School of Medicine 1999-2008; Faculty Pro Vice Chancellor 2008-2015
  • Chair, Medical Schools Council 2009-2013
  • Lecturer in Medicine, University of Cambridge 1989 - 1991
  • Wellcome Senior Clinical Research Fellow, Royal Postgraduate Medical School & University of Cambridge, 1985-1989
  • MRC Travelling Fellow, NIH, USA, 1984-1985
  • MRC Training Fellow, Welsh National School of Medicine 1980-1984

Research:

Research into the pathogenesis of autoimmune endocrine disease, especially thyroid disease. Current projects include the immunogenetics of Graves´ disease and vitiligo, the molecular characterisation of thyroid and parathyroid autoantibodies and work on autoantigen identification in vitiligo, a skin disorder found in increased frequency in Graves´ disease.

Representative Publications (last 5 years):

  1. Jin Y, Birlea SA, Fain PR, Ferrara TM, Ben S, Ricardi SL, Cole JB, Gowan K., Holland PJ, Bennett DC, Luiten RM, Wolkenstorfer A, Van Der Veen JPW, Hartmann A., Eichner S, Schuler G, Van Geel N, Lambert J, Kemp EH, Gawkrodger DJ, Weetman AP, Taieb A, Jouary T, Ezzedine K, Wallace MR, Mccormack WT, Picardo M, Leone G, Overbeck A, Silverberg NB, Spritz RA. Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nature Gen. 2012 44: 676-680.

  2. Kemp EH, Sandhu HK, Watson PF, Weetman AP. Low frequency of pendrin autoantibodies detected using a radioligand binding assay in patients with autoimmune thyroid disease. J.Clin.Endocrinol.Metab. 2013 98:E309-E313.

  3. Walker JN, Shillo P, Ibbotson V, Karavitaki N, Weetman AP, Wass JA, Allahabadia A. A thyroxine absorption test followed by weekly thyroxine administration: a method to assess non-adherence to treatment. Eur J Endocrinol. 2013 168: 913-7.

  4. Kemp EH, Habibullah M, Kluger N, Ranki A, Sandhu HK, Krohn KJE, Weetman AP. Prevalence and clinical associations of calcium-sensing receptor and NALP5 autoantibodies in Finnish APECED patients. J Clin Endocrinol Metab 2014 99: 1064–1071.

  5. Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, Løvås K, Wolff AS, Abramson J, Husebye ES. Dominant mutations in the Autoimmune Regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity 2015 42: 1185-1196.

  6. Jameson JL, Mandel SJ, Weetman AP. Disorders of the thyroid gland. In: Harrison’s Principles of Internal Medicine, 19th Edition, Eds. Braunwald, E., Fauci, A.S., Kasper, D.L., Hauser, S.L.Longo, D.L., Jameson, J.L. 2015 pp2283-2308.

  7. Brent GA, Weetman AP. Hypothyroidism and thyroiditis. In: Williams Textbook of Endocrinology, 13th Edition, Eds. Melmed S., Polonsky K.S., Larsen P.R., Kronenberg H.M., Elsevier, Philadelphia, 2016, pp416-448.


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