The Sheffield Type 1 Diabetes Policy Model

P Thokala, J Kruger, A Brennan, H Basarir, A Duenas, A Pandor, M Gillett, J Elliot, S Heller


The Sheffield Type 1 Diabetes Policy Model is a patient-level simulation model of type 1 diabetes and its associated complications, which was developed as part of the National Institute for Health Research Dose Adjustment for Normal Eating (DAFNE) research programme. The aim of this paper is to describe the conceptual modelling, model implementation, and model validation phases of the Sheffield Type 1 Diabetes Model development process. The model is highly flexible and has broad potential application to evaluate DAFNE, other diabetes structured education programmes, and other interventions for type 1 diabetes.