Confirmed exhibitors at the 8th International Granulation Workshop 2017.
Total Solutions in Particle Characterisation
Microtrac strives to provide the materials characterisation world with innovative, reliable, and repeatable particle size, particle shape, particle charge, and surface area analysis instrumentation.
Microtrac’s instruments deliver insight and solutions to the complex product and process problems a company may experience.
Particle analysis instruments are used in Virtually Every Industry, from pharmaceutical to food processing, even extending to such novel applications as analysis of interplanetary materials like moon rock.
Microtrac particle characterisation instruments are used by top industry professionals to conduct the following analysis:
- Particle Size Measurements
- Zeta Potential Analysis
- 3-D Image Analysis
- Molecular Weight
- Surface Analysis
- Particle Counting
- Dust Characterisation
Freeman Technology specialises in systems for measuring the flow properties of powders and has over 15 years’ experience in powder flow and powder characterisation. The company invests significantly in R&D and applications development, and provides detailed know-how to support its range of products. Expert teams guide and support users around the world in addressing their individual powder challenges, focusing on delivering the most relevant information for the process. The result is world-leading solutions for understanding powder behaviour - in development, formulation, scale-up, processing, quality control, or anywhere that powders have a role.
Freeman Technology’s solutions include the FT4 Powder Rheometer®, a uniquely universal powder tester, and the Uniaxial Powder Tester, a complementary tool for quick and robust powder assessment. Systems are installed around the world in the chemical, pharmaceutical, toners, foods, powder coatings, metals, ceramics, cosmetics, and many other industries. They deliver data that maximise process and product understanding, accelerating R&D and formulation towards successful commercialisation, and supporting the long term optimisation of powder processes.
Freeman Technology is also the global distributor for Lenterra sensor instrumentation which provides in-line, real-time flow measurement solutions to enhance process understanding, and improve manufacturing efficiency and quality.
The company was founded in 1989 as a developer of automated testing systems for materials characterisation, and has focused exclusively on powders since the late 1990s. The company’s R&D, manufacturing and commercial headquarters are in Gloucestershire, UK, with operations in the USA and China, and distribution partners in key global territories.
In 2007 the company received the Queen’s Award for Enterprise in Innovation and in 2012 the Queen’s Award for Enterprise in International Trade.
Integrated Process Solutions
When it comes to fluidised bed technology, Glatt has assumed a pioneering role and is the worldwide leader in integrated process solutions. Glatt offers a unique expertise and product spectrum and a comprehensive support service for pharmaceutical and related powder processing industries. The support service starts with the product development for solid dosage forms and goes far beyond the required process technologies, optionally even covering the planning and installation of the plant required for said technologies. Werner Glatt founded the company in 1954. Today the company has 14 branches and subsidiaries worldwide.
Glatt covers four areas of expertise:
Process Technology Pharma is the original and top-selling area of expertise of the Glatt brand. It includes the core business of fluidised beds for which Glatt has assumed a pioneering role and is considered a worldwide leading supplier. Our Batch processing technology developments started in 1954 and our Continuous processing developments 10 years later in 1964.
Pharmaceutical Services develops and produces solid pharmaceutical dosage forms such as pellets, micro pellets and granulates.
Process Technology Food, Feed & Fine Chemicals develops plans and distributes fluidised and spouted bed systems for the food, feed and chemical industries.
Process & Plant Engineering plans, installs and realises projects in plant construction worldwide. Its spectrum of expertise ranges from the expansion or reorganisation of existing production plants to the construction of new ones – in part or as a whole.
Innopharma Technology specialises in development of efficient, reliable and rapid direct measurement PAT analysers that support research, development and investigational experiments resulting in greater knowledge and more robust manufacturing processes.
Our products provide high quality data and images to understand processes such as Fluid Bed Coating, Fluid Bed Granulation, Twin Screw Granulation, in greater detail helping to reduce time to generate experimental data, scale-up time and product losses resulting on improved yields.
We provide our customers with full support of hardware and software integration from finding the best solutions to better understand the processes to full implementation and after sales support.
Innopharma was founded in 2009 with a vision to develop Process Analytical Technologies to control pharmaceutical tablet manufacturing processes in response to the regulatory impact and market trend of PAT adoption.
(Part of Thermo Fisher Scientific)
Thermo Fisher Scientific is a leading provider in the analytical and laboratory technologies industry, helping the pharmaceutical industry drive innovation and productivity. Our products and services can help you make your drug discovery and development processes faster and more efficient. Our material characterisation solutions offer features and benefits that can span the pharmaceutical market from formulation to manufacturing.
We use continuous processes to allow reliable, one-step scale-up from development to production. If your company’s projects involve any of the following then we can help solve your pharmaceutical challenges:
- Hot melt extrusion
- Continuous granulation
- GMP extrusion
- Online optical spectroscopy
- Analysis of rheological properties and microscopic structure
- Investigating viscoelastic or extensional flow behaviours
Visit our stand to take a closer look at our new Thermo Scientific Pharma 11 – a unique, flexible twin screw extruder for hot melt extrusion and twin screw granulation - helping scientists in the early development of new drug research and development formulation.
Solutions in Particle Sizing
Retsch Technology develops, sells, supports and services the state-of-the-art CAMSIZER range of optical measuring systems for particle characterization measuring both Particle Size and Shape by Digital Image Analysis:
Measuring range from 0.8 micron to 30mm
Analysis of particle size and shape of colloidal materials, emulsions, suspensions, dispersions, powders and granulates.
Dynamic Image Analysis (Digital Image Processing) is an established method, along with sieve analysis and laser diffraction for particle size analysis. This method is superior to the others in its resolution, precision and reproducibility and delivers additional detailed particle shape information. Typical analysis time is 3 to 5 minutes with excellent reproducibility.
Sympatec develops, manufactures, sells, services and supports an innovative range of best instruments for particle size and shape analysis in laboratory and process for customers worldwide.
With continuous innovations in the technological fields of laser diffraction, dynamic image analysis, ultrasonic extinction and photon cross-correlation spectroscopy (PCCS) Sympatec makes a prominent contribution to the development, production and quality control of most challenging particulate systems.
Typical applications cover dry powders and granules, fibres, suspensions, emulsions, gels, sprays and inhalants within a size range from 1 nm to 30,720 µm. Modular instruments show great versatility and can be adapted to the specific task within your laboratory. The proven measurement technologies are also available for integration into your process. Moreover, the instruments reliably deliver most accurate, reproducible and comparable results at shortest measuring times.
Surface Measurement Systems Ltd.
Surface Measurement Systems develops and engineers innovative experimental techniques and instrumentation for physico-chemical characterisation of solid state materials.
We are the world leaders in Dynamic Vapor Sorption technology and Inverse Gas Chromatography instrumentation and solutions, providing professional world-class scientific and technical support for our international customers.
Inverse Gas Chromatography - Surface Energy Analyzer (iGC-SEA)
This system is specially designed to determine the surface energy heterogeneity but nevertheless suitable for measuring different surface and bulk properties of solid materials including acid / base properties, heat of sorption, glass transition temperature, solubility parameters and so on.
Dynamic Vapour Sorption (DVS)
This system allows for real-time monitoring and controlling of vapor and gas concentration for sorption measurements in solid state materials. The sorption mechanism may be investigated from sorption / desorption isotherms and hysteresis effects. The combination of a video microscope and vibrational spectroscopic techniques with DVS would allow for increased understanding of vapor-induced structural changes of solid materials. The DVS Vacuum can offer measurements on vapour pressure and heat of evaporation of solids, low pressure vapour/gas sorption and vacuum drying.
Humidity Generation Systems (GenRH)
This system allows for precise humidity generation and delivery to sample enclosures and multiple analytical techniques including microscopy stage and FT – IR.
Particle Processing Equipment & Service Provider
ProCepT has 20 years’ experience in particle processing technology.
We specialize in development of lab-scale R&D equipment (mg to kg).
We supply process equipment; Spray Dryer - Congealer / Fluidbed / Tablet Coater / High Shear Granulator - Vacuum Dryer / Extruder / Nutsche Filter Dryer.
Our engineering concept is based on Modularity, Visibility, Accuracy and Customization.
Xedev, a spin out from ProCepT, is a Service Provider in Particle Engineering and Process Development, operating under a “fee for service” principle.
We make the difference by combining expertise in Process, Formulation and Analytics with Equipment Engineering.
Xedev offers services from a one day process feasibility run to complete process & formulation development, technology transfer, scale-up and analytical support.
ProCepT and Xedev support Pharma, Biotech, Chemical, Food, Cosmetic and Agro industries.
- Standard extruders for multifunction extrusion of smallest quantities up to production scale in lab, test and production applications.
- Hybrid extruders, a new mini-extruder built in a table top execution. As a twin barrel extruder, two different screw diameters can be run on the same device. 5, 9, 12 mm diameter screws are possible.
- High containment extruders and feeding units together with peripherals such as spheronisers, granulators, hot die faces, conveyor belts and water baths.
- Flat tray feeders, standard feeders and quick clean feeders providing precise volumetric and gravimetric feeding.
- Pelletisers, compactors and filling plants.
Specialist in particle technology:
- Continuous fluid bed plants
- Batch fluid bed technology
- Roll grinders
Neuhaus Neotec specialises in building plants for the food industry, the fine chemistry, the chemical and the pharmaceutical industries. In mechanical engineering for the processing of coffee, we are one of the world's leading manufacturers. With the takeover of the company Heinen Drying in 2010, we have expanded our business area "Particle technology". Based on this extensive know-how we develop fluidised bed plants for continuous as well as discontinuous (batch) operation.
- Fluid bed drying
- Spray drying agglomeration
- Fluid bed spray granulation
In our professional pilot plant, we simulate your individual requirements on a laboratory scale, optimise product properties and test process parameters for large production plants.
UK agent Orthos Engineering Ltd represents both ALEXANDERWERK and EIRICH, two companies with a long history in granulation technology.
Alexanderwerk specialises in the development and production of roller compaction and granulation machines for the chemical and pharmaceutical industries. With their WP 120 Pharma unit (as seen at University of Sheffield) Alexanderwerk offers a roller compactor specifically designed for use in R&D departments or small scale production. Even batches of as little as 5g can be processed on the WP 120 Pharma.
Their R-type intensive mixer was developed for the most diverse jobs in the processing of raw materials, mechanical mixtures and compounds. Variable setting of machine components and the input energy range ensures a high degree of efficiency. With their EL1 unit (as seen at University of Sheffield) Eirich offers a high shear mixer granulator specifically designed for use in laboratories.
GEA is a trusted provider of process technology and packaging solutions for the pharmaceutical, biopharmaceutical, biotechnology and nutraceutical industries. Our portfolio includes single units, modular systems and complete production lines for powder processing, oral solid dosage forms, parenterals, sterile liquids and semi-solids.
Experts in tablet compression, coating, continuous manufacturing and containment, we offer the largest variety of process technologies and boast an unrivalled history of identifying the most appropriate solution for your specific application.
GEA provides proven solutions for the most challenging dosage forms, such as oncology drugs, multiple unit pellet system (MUPS) tablets, effervescents and multilayer pellets. Also, as experts in containment, we supply a wide range of solutions for contained processing — based on a deep understanding of containment risk analysis — to identify the most appropriate solution.
Significant technical advances have been achieved in recent years, enhancing the performance of granulation technology and allowing optimal solutions to be identified for every product mix and production combination. GEA has been a constant leader in the field, driving these developments and endeavouring to provide the right solution for your granulation application.
And, in May this year, representing our continued commitment and ongoing support for the current and future pharmaceutical industry, we opened the recently expanded GEA Pharma Solids Center (GPSC) in Wommelgem, Belgium, a state-of-the-art facility for solid dosage form testing, development and optimisation.
Ytron-Quadro’s technology based solutions to processing requirements for the Pharmaceutical, Cosmetic, Food and Chemical industries are based on many years of experience within the processing industry.
Originally supplying the Quadro Comil from Quadro Engineering and liquid mixing and air free powder incorporation systems from Ytron GmbH, our capabilities now cover a much wider range of process technologies from Fitzpatrick, for dry granulation with the CCS range of roller compaction systems, to sampling devices for powders and liquids from Labocontrole, together with gel, cream and paste manufacturing using rotor/stator systems both inline and within vacuum mixing vessels from VMI.
S3 Process supplies the leading powder processing equipment to pharmaceutical manufacturers throughout the UK and Ireland. With our experienced team of consultants and project managers, we support clients through design, build, testing, installation and validation to ensure every piece of process equipment is delivered as part of a fully integrated solution.
Committed to the continuous improvement of process manufacturing, we cooperate with clients to identify process innovations that can deliver tangible efficiencies. Combining the very best process equipment with innovative techniques, our clients see significant improvements in quality, scale-up and production times, manufacturing costs, personal safety and overall manufacturing sustainability.
Partnering with the leading technology manufacturers including Frewitt milling and sieving systems, Gerteis dry granulation roller compactors, GEA continuous wet granulation and drying, GEA single pot granulation and drying systems, GEA tablet compression, and O’Hara tablet coaters, S3 Process helps identify and deliver the most suitable equipment for each of your process applications.
Improving Tablet Quality
We provide high performance instruments, support and training to help scientists in creating innovative products.
To create new and better products you need to carefully study and understand the relationship between drug properties, formulation and manufacturing process under properly controlled laboratory conditions.
Until recently small scale tablet manufacture using ‘controlled compaction force’ had not been possible because of technical limitations based on thickness control and large scale production.
New breakthroughs by Gamlen Instruments mean that scientists now have the ability to manufacture small batches of tablets and conduct advanced research and development using portable benchtop instruments.
The Tableting Instruments Company
Medelpharm, headquartered in Lyon, South-East France, is a high-precision engineering company manufacturing R&D tablet presses, and providing innovative solutions for powder analysis and formulation.
Since spring 2017 Medelpharm has its own laboratory which is under controlled atmosphere to perform powder characterization and analysis. It houses amongst the latest innovative measuring equipment, the Styl’One Tableting Instrument, Smart test 50 and a Tablet and Mini Coater /Drier for coating of minimal quantities of powder,and a multifunction mill and sifter.
Medelpharm multilayer STYL’One Evolution Tableting Instrument is a high-speed R&D tool, capable of mimicking production presses with only a few grams of powder analysing data from early formulation to scale-up at production speed. Critical QbD rules are always in our mind.
So far the STYL’One Tableting Instrument has been installed around 100 times world-wide.
The distribution of the STYL’One Tableting Instruments s is part of a global partnership with the Romaco Kilian Group.
Besides manufacturing R&D tablet presses, Medelpharm distributes renowned and innovative technologies in powder processing with brands like
- LB BOHLE
Process Systems Enterprise
PSE is the world’s foremost provider of Advanced Process Modelling software and services to the process industries. Companies apply advanced process models to explore the process decision space rapidly and effectively, in order to reduce uncertainty and make better, faster and safer formulation, process design and operating decisions.
PSE provides the gPROMS FormulatedProducts modelling suite for optimising the formulation and manufacture of drug substances and drug products using mechanistic process and material models of unit operations – such as crystallization, spray drying and granulation – combined with in-vitro/vivo product performance models.
Use of PSE’s technology and services results in faster innovation, more rapid formulation screening, improved process and product designs, enhanced operations, reduced risk, more effective R&D and experimental campaigns and better capture and transfer of corporate knowledge across the organisation.
The company is pioneering the emerging science of Systems-based Pharmaceutics with Eli Lilly, Pfizer, GSK and Roche, and is the leader of the £20.4m digital design ADDoPT project.
International Granulation Workshops
The Granulation Conference showcases the latest in agglomeration, granulation and particle technology.
We welcome your abstracts for oral or poster presentations, or any enquiries that you may have.
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