Dr Hanya Mahmood

BDS (Birm), MFDS RCS, PGDip Con Sed, PGCert Med Ed, FHEA, MClinRes, MOralSurg, PhD

School of Clinical Dentistry

Senior Clinical Lecturer & Honorary Consultant Oral Surgeon

h.mahmood@sheffield.ac.uk
+44 114 215 9370

19 Claremont Crescent

Full contact details

Dr Hanya Mahmood
School of Clinical Dentistry
19 Claremont Crescent
Sheffield
S10 2TA

Profile

Dr Mahmood graduated from the University of Birmingham in 2012. Following this, she completed Dental Foundation Training (2012-2013) and multiple Dental Core Training posts in Oral & Maxillofacial Surgery, Oral Medicine, Oral Pathology and Radiology (2012-2018). During this time, she gained MFDS at the Royal College of Surgeons of Edinburgh, Postgraduate Certificate in Medical Education (2017), Fellowship of the Higher Education Academy (2017) and Diploma in Conscious Sedation (Merit, 2018). She was subsequently appointed as an NIHR Academic Clinical Fellow in Oral Surgery during which she completed higher surgical training with award of MOralSurg (2021).

She has a strong track record in research, having completed a Masters in Clinical Research (Distinction, 2021) and a prestigious NIHR Doctoral Research Fellowship (2021-2024) which supported her PhD in the application of Artificial Intelligence to aid early oral cancer detection. She has received several national and international research prizes, including the most coveted PhD-level UK research prize for Oral & Dental Research, the Senior Colgate Award (2023) in addition to the IADR Oral Medicine & Pathology Research Prize (2022), ABAOMS Research Prize (2023) and BSOMP Potts Research Prize (2022). She was promoted to Senior Clinical Lecturer & Honorary Consultant Oral Surgeon at the School of Clinical Dentistry, (University of Sheffield) in 2024.

Research interests

Dr Mahmood’s main research focus is the study of oral precancer progression to malignancy. She is a key member of the NEOPATH research group leading innovation in oral, head and neck cancer research. Her NIHR funded PhD (worth £353K) developed novel digital, computational and quantitative models for oral cancer risk prediction (supervisors Professors Syed Ali Khurram, Daniel Lambert and Nasir Rajpoot) and received various national and international research prizes.

She is involved in a number of national and international collaborative projects exploring novel digital and spatial biomarkers in oral cancers and pre-cancers using state-of-the art approaches, including AI, Deep Learning, single-cell analysis and multiplex imaging.

Publications

Journal articles

Shephard AJ, Bashir RMS, Mahmood H, Jahanifar M, Minhas F, Raza SEA, McCombe KD, Craig SG, James J, Brooks J , Nankivell P et al (2024) A fully automated and explainable algorithm for predicting malignant transformation in oral epithelial dysplasia. npj Precision Oncology, 8(1). View this article in WRRO
Hankinson P, Mahmood H, Walsh H, Speight PM & Khurram SA (2024) Demystifying oral epithelial dysplasia: a histological guide. Pathology, 56(1), 11-23.
Sathyamoorthy H, Mahmood H, Zubir AZA, Hankinson P & Khurram SA (2024) Prognostic importance of mitosis quantification and PHH3 expression in oral epithelial dysplasia. Virchows Archiv, 484, 47-59. View this article in WRRO
Mahmood H, Shephard A, Hankinson P, Bradburn M, Araujo ALD, Santos-Silva AR, Lopes MA, Vargas PA, McCombe KD, Craig SG , James J et al (2023) Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia. British Journal of Cancer, 129(10), 1599-1607. View this article in WRRO
Bashir RMS, Shephard AJ, Mahmood H, Azarmehr N, Raza SEA, Khurram SA & Rajpoot NM (2023) A digital score of peri-epithelial lymphocytic activity predicts malignant transformation in oral epithelial dysplasia. Journal of Pathology, 260(4), 431-442.
Mahmood H, Hankinson P, Andrew D, Nusrath M & Khurram SA (2022) Radiation‐induced osteosarcoma involving the mandible – report of a rare diagnosis. Oral Surgery.
Mahmood H, Hoare J & Atkins S (2022) Chemical neurotoxicity to the inferior alveolar nerve — a rare sequela of endodontic treatment. Oral Surgery, 15(4), 663-668. View this article in WRRO
Mahmood H, Bradburn M, Rajpoot N, Islam NM, Kujan O & Khurram SA (2022) Prediction of malignant transformation and recurrence of oral epithelial dysplasia using architectural and cytological feature specific prognostic models. Modern Pathology, 35, 1151-1159. View this article in WRRO
Wilson C & Mahmood H (2021) COVID-19 treatment and MRONJ. Faculty Dental Journal, 12(3), 111-112.
Wilson CL, Mahmood H, Varley I, Khurram AS, El-Awa A & Steel C (2021) UNUSUAL LIP TUMORS: A CASE SERIES. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 132(1), e52-e53.
Mahmood H, Shaban M, Rajpoot N & Khurram SA (2021) Artificial Intelligence-based methods in head and neck cancer diagnosis : an overview. British Journal of Cancer, 124(12), 1934-1940.
Anabtawi M, Tweedale H & Mahmood H (2021) The role, efficacy and outcome measures for teriparatide use in the management of medication-related osteonecrosis of the jaw. International Journal of Oral and Maxillofacial Surgery, 50(4), 501-510. View this article in WRRO
Camalan S, Mahmood H, Binol H, Araújo ALD, Santos-Silva AR, Vargas PA, Lopes MA, Khurram SA & Gurcan MN (2021) Convolutional neural network-based clinical predictors of oral dysplasia: class activation map analysis of deep learning results. Cancers, 13(6). View this article in WRRO
Mahmood H, Shaban M, Indave BI, Santos-Silva AR, Rajpoot N & Khurram SA (2020) Use of artificial intelligence in diagnosis of head and neck precancerous and cancerous lesions: A systematic review. Oral Oncology, 110. View this article in WRRO
Wilson CL, Mahmood H & Loescher A (2020) Clinical presentations on a facial pain clinic. British Dental Journal.
Anabtawi M, Wege J, Mahmood H, Dareen Amro BA & Patterson A (2020) Nodular eruptions as a rare complication of botulinum neurotoxin type-A : case series and review of literature. Cureus, 12(8). View this article in WRRO
Mahmood H, Siddique I & McKechnie A (2020) Antiplatelet drugs : a review of pharmacology and the perioperative management of patients in oral and maxillofacial surgery. Annals of the Royal College of Surgeons of England, 102(1), 9-13. View this article in WRRO
Mahmood H, Stern M & Atkins S (2019) Inferior alveolar nerve anaesthesia : a rare complication of orthodontic tooth movement. Journal of Orthodontics, 46(4), 374-377. View this article in WRRO
Mahmood H, Murphy C & Oktseloglou V (2018) Cystadenoma of the mandible : a rare presentation. British Journal of Oral and Maxillofacial Surgery, 56(6), 540-542. View this article in WRRO
Mahmood H, Flora H, Murphy C & Sutton D (2018) Retrobulbar abscess : rare complication after repair of an oroantral communication. British Journal of Oral and Maxillofacial Surgery, 56(3), 227-229. View this article in WRRO
Mahmood H & Chengot P (2017) Primary malignant gingival melanoma : case report and educational reminder. Oral Surgery, 10(4), e88-e91. View this article in WRRO
Mahmood H, Siddique I & Mohammed-Ali R (2015) Analgesia overdose due to dental pain requiring acute hospital admissions. British Journal of Oral and Maxillofacial Surgery, 53(10), e79-e80.
Siddique I, Mahmood H & Mohammed-Ali R (2015) Paracetamol overdose secondary to dental pain: a case series. British Dental Journal, 219(6), E6-E6.
Mahmood H, White L, Li T & Mohammed-Ali R (2014) Third Molar Extractions: Are we over prescribing the Cone Beam CT?. British Journal of Oral and Maxillofacial Surgery, 52(8), e101-e101.
Shephard AJ, Mahmood H, Raza SEA, Khurram SA & Rajpoot NM () A novel AI-based score for assessing the prognostic value of intra-epithelial lymphocytes in oral epithelial dysplasia. British Journal of Cancer.

Chapters

Azarmehr N, Shephard A, Mahmood H, Rajpoot N & Khurram SA (2022) A Neural Architecture Search Based Framework for Segmentation of Epithelium, Nuclei and Oral Epithelial Dysplasia Grading, Lecture Notes in Computer Science (pp. 357-370). Springer International Publishing

Conference proceedings papers

Shephard A, Mahmood H, Raza S, Khurram A & Rajpoot N (2024) ODYN: an artificial intelligence-based pipeline for the prediction of malignant transformation in oral epithelial dysplasia. VIRCHOWS ARCHIV, Vol. 485 (pp S46-S47)
Shephard A, Mahmood H, Raza SEA, Khurram A & Rajpoot N (2024) A novel artificial intelligence-based score for assessing the prognostic value of intra-epithelial lymphocytes in oral epithelial dysplasia. VIRCHOWS ARCHIV, Vol. 485 (pp S120-S120)
Shephard AJ, Graham S, Saad Bashir RM, Jahanifar M, Mahmood H, Khurram SA & Rajpoot NM (2021) Simultaneous Nuclear Instance and Layer Segmentation in Oral Epithelial Dysplasia. 2021 IEEE/CVF International Conference on Computer Vision Workshops (ICCVW), 11 October 2021 - 17 October 2021.
Saad Bashir RM, Mahmood H, Shaban M, Ahmed Raza SE, Fraz MM, Khurram SA & Rajpoot NM (2020) Automated grade classification of oral epithelial dysplasia using morphometric analysis of histology images. Medical Imaging 2020: Digital Pathology(11320). Houston, Tx, United States, 15 February 2020 - 15 February 2020. View this article in WRRO
Mahmood H, Smith A & Khurram SA (2020) Lichen sclerosus et atrophicus - an extremely rare diagnosis of the oral cavity. VIRCHOWS ARCHIV, Vol. 477 (pp S318-S319)
Mahmood H, Shaban M, Indave I, Santos-Silva A, Rajpoot N & Khurram SA (2020) Artificial intelligence to aid the diagnosis of head and neck precancerous and cancerous lesions: a systematic review. VIRCHOWS ARCHIV, Vol. 477 (pp S37-S37)
Mahmood H, Andrew D & Khurram SA (2020) Radiation-induced osteosarcoma involving the mandible - report of a rare diagnosis. VIRCHOWS ARCHIV, Vol. 477 (pp S319-S319)
Mahmood H & Khurram SA (2020) Prognostic significance of oral dysplasia features - analysis of a preliminary cohort. VIRCHOWS ARCHIV, Vol. 477 (pp S21-S22)

Preprints

Shephard AJ, Mahmood H, Raza SEA, Damaceno Araujo AL, Santos-Silva AR, Lopes MA, Vargas PA, McCombe KD, Craig SG, James J , Brooks J et al (2024) Development and Validation of an Artificial Intelligence-based Pipeline for Predicting Oral Epithelial Dysplasia Malignant Transformation, Cold Spring Harbor Laboratory.
Shephard AJ, Mahmood H, Raza SEA, Khurram SA & Rajpoot NM (2024) A Novel AI-based Score for Assessing the Prognostic Value of Intra-Epithelial Lymphocytes in Oral Epithelial Dysplasia, Cold Spring Harbor Laboratory.
Shephard AJ, Mahmood H, Raza SEA, Araujo ALD, Santos-Silva AR, Lopes MA, Vargas PA, McCombe K, Craig S, James J , Brooks J et al (2023) Transformer-based Model for Oral Epithelial Dysplasia Segmentation, arXiv.
Rajpoot N, Shephard A, Bashir R, Mahmood H, Jahanifar M, Minhas F, Raza SEA, McCombe K, Craig S, James J , Brooks J et al (2023) A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia, Research Square Platform LLC.
Shephard AJ, Bashir RMS, Mahmood H, Jahanifar M, Minhas F, Raza SEA, McCombe KD, Craig SG, James J, Brooks J , Nankivell P et al (2023) A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia, arXiv.
Bashir RMS, Shephard AJ, Mahmood H, Azarmehr N, Raza SEA, Khurram SA & Rajpoot NM (2023) A digital score of peri-epithelial lymphocytic activity predicts malignant transformation in oral epithelial dysplasia, Cold Spring Harbor Laboratory.
Shephard AJ, Graham S, Bashir RMS, Jahanifar M, Mahmood H, Khurram SA & Rajpoot NM (2021) Simultaneous Nuclear Instance and Layer Segmentation in Oral Epithelial Dysplasia, arXiv.

Research group

As part of the NEOPATH Research Group, she works closely with Professor Ali Khurram to supervise and mentor clinical academic trainees, postgraduate and post-doctoral research students to drive forwards translational projects in oral, head and neck cancer research.

Clinical trainees

Chris Platais
Mollie Clark
Alizey Kazmi (HEYH Flexible Portfolio)

Masters students

Hrishikesh Sathyamoorthy (MMedSci - completed)
Najla Nadiah (MMedSci - completed)

Teaching interests

Dr Mahmood has completed a PGCert in Medical Education and obtained Fellowship of the Higher Education Academy (2017).

She provides regular hands-on practical teaching in Oral Surgery to undergraduates, postgraduates and clinical trainees. She provides formal teaching to BDS students as part of the Integrated Clinical Practice, Oral Diseases and Integrated Human Diseases courses.

She is a personal tutor to BDS students, a registered Clinical Supervisor for speciality trainees in Oral Surgery, and a trained peer mentor for postgraduates in the Yorkshire & Humber Deanery.

She teaches on the Sheffield Implant Foundation Course and has previously led the RCS MFDS exam webinars for Oral Surgery broadcast to students in the UK, Burma and Kuala Lumpur (2017-2019).

Professional activities and memberships

Current roles

Scientific Advisor, British Dental Association Health & Science Committee (since 2022)
Member, Research Working Group, Salivary Gland Cancers UK (since 2024)
Member, INTERCEPTOR Research Working Group (since 2024)
Member, Scientific Advisory Board for Fanconi Hope (since 2024)
Member, Sheffield University Research Integrity Steering Group (since 2024)
Chair, ABAOMS Education Committee (since 2023)
Sheffield Representative, Dental Sedation Teachers Group (since 2023)
Lead, Sedation Journal Club, Charles Clifford Dental Hospital (since 2020)
Member of learned societies: BAOS, ABAOMS, BDA, BSOMP, IADR, BSODR, DSTG
Reviewer for Oral Surgery Journal, British Dental Journal & British Journal of Cancer

Previous roles

Academic Trainee Representative & Webmaster, ABAOMS (2018 – 2024)
Trainee Representative, Sheffield Hospitals Junior Doctor Forum (2018-2023) & Oral & Dental Research Directorate (Charles Clifford Hospital, 2021-2023)
Member, Athena Swan Assessment Team (School of Clinical Dentistry, 2023-2024)
BAOS Yorkshire Regional Representative (2018-2019)

Clinical treatments: Dr Mahmood provides a range of oral surgical treatment under local anaesthetic, conscious sedation and general anaesthetic. Her main clinical interests include the management of medically compromised patients and treatment of oral soft/hard tissue disease and pathology.