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Healthy Lifespan Institute

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  • About
    • About
      • Mission
      • Who we are
      • Ageing explained
      • News
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      • Core team and directors
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      • PhD study at Sheffield
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Understanding multimorbidity and frailty

Identifying the biological and molecular mechanisms common to multiple age-related diseases, as well as the wider environmental, social and and genetic factors that modulate multimorbidity as we age.

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Biological mechanisms of ageing, multimorbidity and frailty

Led by Professor Sherif El-Khamisy, we are identifying biological pathways and molecular mechanisms driving ageing and common causes to cardiovascular, musculoskeletal, neurodegenerative diseases and cancer and providing targets for drug interventions to prevent multimorbidity and boost resilience in individuals with frailty.

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Artificial intelligence for multimorbidity and frailty

Led by Dr Maria-Cruz Villa-Uriol and Venet Osmani, we are identifying determinants and predictors of multimorbidity (including socio-economic and environmental factors/biological processes) using Artificial Intelligence approaches.

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Medical imaging

Biomarkers and imaging

Led by Professor Steven Sourbron, we're using medical imaging biomarkers to improve our understanding and management of multimorbidity and organ interactions in human disease. We offer infrastructure, technical solutions and support for integrating medical imaging biomarkers as primary or secondary endpoints in clinical or preclinical research.

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Developing interventions
Knowledge exchange and capacity building

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