Dr Elizabeth Williams

Department of Oncology & Metabolism
Human Nutrition Unit
The University of Sheffield Medical School
Beech Hill Road
Sheffield
S10 2RX

Office: GU29

Tel: +44 (0)114 215 9065
Fax: +44 (0)114 271 3314


email: e.a.williams@sheffield.ac.uk

Biography

I trained in Physiology at The University of Sheffield and continued at Sheffield for my postgraduate studies investigating the role of riboflavin deficiency on gastrointestinal development. I was awarded my PhD in 1996 and was then appointed as a Postdoctoral Researcher at the MRC Dunn Nutrition Unit, Cambridge and worked at a MRC field station in The Gambia, West Africa. On my return to the UK I was appointed as a Lecturer in Human Nutrition at Newcastle University. In 2003 I returned to Sheffield and joined the Human Nutrition Unit as a Lecturer. I was promoted to Senior Lecturer in 2010.

Research Interests

I have a long-standing research interest in diet and intestinal health and, in particular, biomarkers of colorectal cancer, and the role of butyrate and folate on colorectal carcinogenesis.

I also have a research interest in the nutrition, health and wellbeing of older adults. This includes an interest in the relationship between diet, immune function and ageing, and the assessment of dietary intake in older adults. The work has developed through collaboration with colleagues in Sheffield (Profs Pockley, Powers and Parker) and beyond (University of St Andrews, Reading University and Bath Institute of Mechanical Engineering).

Teaching Interests

My primary teaching responsibilities are within the Human Nutrition Unit. The Unit runs a 12-month MMedSci and a 9-month Postgraduate Diploma in Human Nutrition. The Masters programme consists of 6 taught modules and a 5-month research project. I am responsible for the design, delivery and assessment of the 15 credit Nutritional Physiology module on the course.

Professional Activities

Nutritional Genomics Theme Leader, The Nutritional Society.

Current Projects

I am the Sheffield principal investigator on the NANA project. Novel assessment of Nutrition in Ageing. The NANA project is a multidisciplinary study funded by ESRC as part of the New Dynamics of Ageing (NDA) programme.

Key Publications

  1. Forster SE, Jones L, Saxton JM, Flower DJ, Foulds G, Powers HJ, Parker SG, Pockley AG, Williams EA. (2010) Recruiting older people to a randomised controlled dietary intervention trial - how hard can it be? BMC Med Res Methodol. 2010 Feb 22;10(1):17.
  2. Caple F, Williams EA, Spiers A, Tyson J, Burtle B, Daly AK, Mathers J, Hesketh JE (2010) Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype. British Journal of Nutrition 19:1-9
  3. Hill MH, Mushtaq S, Williams EA, Dainty JR, Powers HJ. (2009) Study Protocol: randomised controlled trial to investigate the functional significance of marginal riboflavin status in young women in the UK (RIBOFEM). BMC Public Health 26;9:90
  4. Hill MH, Bradley A, Mushtaq S, Williams EA, Powers HJ. (2009) Effects of methodological variation on assessment of riboflavin status using the erythrocyte glutathione reductase activation coefficient assay. British Journal of Nutrition. 102:273-278.
  5. Croucher LJ, Bury JP, Williams EA, Riley SA, Corfe, BM. (2008) Commonly used bowel preparations have significant and different effects upon cell proliferation in the colon: a pilot study BMC Gastroenterology 2008 Nov 14;8:54
  6. Tyson, J, Caple F, Spiers A, Burtle B, Daly A, Williams EA, Hesketh JE, Mathers JC. (2008) Inter-individual variation in nucleotide excision repair in young adults:effects of age adiposity, micronutrient supplementation and genotype. British Journal of Nutrition. Oct 7:1-8
  7. Williams EA, Stimpson J, Wang D, Garaiova I, Plummer S, Barker ME, Corfe BM. (2008) Clinical trial: a multistrain probiotic preparation significantly reduces symptoms of irritable bowel syndrome in a double-blind placebo-controlled study. Alimentary Pharmacology & Therapeutics 101(9):1316-23
  8. Powers HJ, Hill MH, Bal W, Spiers A, Welfare M, Russell J, Williams EA†, Mathers JC. (2007) Responses of biomarkers of folate and riboflavin status to folate and riboflavin supplementation in healthy and adenomatous polyp patients. Cancer Epidemiology, Biomarkers and Prevention. 16 (10):2128-35 †Joint last author 

For a full list of publications please visit myPublications