The University of Sheffield has invested £1.5 million in a state of the art 7 Tesla Magnetic Resonance Imaging (MRI) facility. One Tesla is nearly 20,000 times the strength of Earth magnetic field. Most common "Clinical MRI" scanners operate at 1.5 and 3.0 Tesla magnetic field. The use of higher magnetic field results in higher quality detailed images, which in particular can permit detection of subtle changes in tissue properties in the body.
Thus, our 7T MRI provides an opportunity to explore aspects of cellular and preclinical imaging that can be more easily translated to clinical research. For example we can measure magnetic properties of ultra-small magnetic particles in a test tube or in a body (blood/tissue). We can distinguish cancerous tissue from normal tissue, and we can validate disease phenotypes in transgenic and xenograft small animal models. Finally we can assess efficacy of selective therapeutics that are able to target diseased organs (brain, heart, liver, kidney, muscle, and bone etc.) in these animal models.
Furthermore, our user supportive MRI staff aim to help both internal and external scientists meet their research goals through the use of novel multidimensional (1d & 2d) proton and X-nuclei spectroscopy, ultra-fast structural and functional imaging methodologies, which may then assist translational researchers, and clinicians discover novel MR associated biomarkers that may lead to better clinical trials in patients.