Cardiac-MRI predicts clinical worsening and mortality in Pulmonary Arterial Hypertension

Insigneo member Dr Samer Alabed (Cardiac MRI Research Fellow at the University of Sheffield’s Department of Infection, Immunity and Cardiovascular Disease) and colleagues have published a new meta-analysis in JACC: Cardiovascular Imaging.

Cardiac Magnetic Resonance Imaging figure
Figure: Cardiac Magnetic Resonance Imaging for Prediction and Mortality in Pulmonary Arterial Hypertension

The new meta-analysis in JACC: Cardiovascular Imaging confirms Cardiac magnetic resonance (CMR) imaging is an especially effective tool for evaluating patients with pulmonary arterial hypertension (PAH).

The researchers concluded that “CMR can predict clinical worsening, in addition to confirming its prognostic role, in a large cohort of patients with PAH.

"This study provides a strong rationale for considering CMR as a clinical trial endpoint.”

They added, too, that “our findings highlight the clinical utility of CMR imaging and support further evaluation of this modality as a clinically meaningful trial endpoint for the assessment of new therapies for PAH.”

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Article

Cardiac-MRI Predicts Clinical Worsening and Mortality in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis (JACC: Cardiovascular Imaging) S. Alabed, Y. Shahin, P. Garg, F. Alandejani, C. S. Johns, R. A. Lewis, R. Condliffe, J. M. Wild, D. G. Kiely, A. J. Swift

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