Bridging the Age Gap in Breast Cancer

Bridging the Age Gap is an NIHR funded study that aims to optimize the management of older women and reduce the age-gap in cancer outcomes between older and younger women with breast cancer by:

  1. Developing a predictive tool to tailor treatment options for older women according to breast cancer factors and their fitness/frailty
  2. Developing a Decision Support Instrument (DESI) to assist older women making informed decisions about their preferred treatment

The study is now open in 57 centres around England and Wales, and is expected to continue recruiting until March 2018.

Read our recent news highlights below.

Study Background

Phase 2

The Cohort study has now transitioned into Phase 2. 36 sites now have R&D approval and have transitioned to the new protocol. 

For more information:

Christmas Closure

The Age Gap office will be short staffed from 16th December until 2nd January.

Please contact us by email with any urgent queries over the Christmas holidays.


We have now recruited over 3200 women to the trial, which means we have reached our target for the Cohort study. However, the RCT is not on schedule, and we still need around 350 more recruits in order to reach our target. We will now continue to recruit to the RCT until 31st March 2018.

November 2017 recruitment is now available here:

Study Extension

To reach our RCT target of 1500 women, the study has been extended, and will now close at the end of March 2018.