Workshop programme

Lecture 1: Introduction to continuous granulation

Practical session 1

Continuous granulation line (Consigma 25):

• Overview of the unit operations of the line
• Assembling/ disassembling the twin screw granulator (TSG)
• Overview of the control panel
• Creating recipe and starting up a campaign
• Critical process parameters in the TSG and effect on the granule critical quality attribute (CQA)

Practical session 2

Segmented fluidised bed, cone mill and the blending unit:

• Overview of individual unit operations.
• The critical process parameters of individual unit operations and their effect on the granule CQA

Practical session 3

Module P tablet press:

• Overview of the Module P tablet press
• The critical process parameters
• Tablet critical quality attributes

Lecture 2: Fluidised bed dryer

Break

Practical session 4

• Tracing and monitoring the feed powder and the products through the complete continuous line.
• Effect of the process and formulation parameters of the twin screw on the final tablet properties

Practical session 5

• Effect of the fluidised bed, milling and blending unit process parameters on the final tablet properties 

Practical session 6 

• Operating the whole line in automatic mode
• Extracting the data and how to track the data for an individual cell
• Finishing and shutting down the whole line