EU Funding Success for Kevin Gurney: "'NoTremor' - Virtual, Physiological and Computational Neuromuscular
Models for the Predictive Treatment of Parkinson’s Disease



We are very pleased to announce the success of an FP7 bid with the Sheffield component (work 411,000 Euros) led by Kevin Gurney. This is for a FP7 ICT project  titled “’NoTremor' - Virtual, Physiological and Computational Neuromuscular Models for the Predictive Treatment of Parkinson’s Disease".

The Sheffield component is in collaboration with Sean Anderson from ACSE and will employ Alex Blenkinsop (a graduate of our CCN MSc) as a postdoc. The abstract is below:


Abstract
NoTremor aims to provide patient specific computational models of the coupled brain and neuromuscular systems that will be subsequently used to improve the quality of analysis, prediction and progression of Parkinson’s disease. In particular, it aspires to establish the neglected link between brain modelling and neuromuscular systems that will result in a holistic representation of the physiology for PD patients.  NoTremor will integrate computational models of the basal ganglia and brainstem into a unique multi-scale parametric computational model that can be subsequently simulated in the NoTremor simulation engine in a physics-based manner.  UCB Pharma aims to incorporate the NoTremor computational modelling and simulation approach in their drug development pipeline that is expected to significantly boost the efficiency and personalization of new drugs.