International Health Technology Assessment and Reimbursement (Online)

Core modules:

Methods and Processes in International Health Technology Assessment

This module outlines the process of Health Technology Assessment and sets out the framework by which companies may develop Therapeutic Value Propositions (TVPs), i.e. positions in a disease management pathway where a new technology may add value in terms of effectiveness, safety or cost. The module covers identification and synthesis of evidence to construct disease management pathways, and how to pinpoint areas of unmet need. It also covers an introduction to the types of evidence needed to demonstrate clinical and cost-effectiveness, including clinical trial design as well as non-trial evidence.

15 credits

Systematic Reviews and Evidence Synthesis: Principles DL

The purpose of this unit is to enable students to understand the principles of systematic review. It covers the defining characteristics and application of systematic reviews; how to search for and select relevant evidence; how to quality assess primary research articles; the key issues that may generate bias; and the general principles governing evidence synthesis.

15 credits

International Healthcare Systems and Reimbursement DL

This module introduces students to the range of healthcare and reimbursement systems to be found throughout the world, considering tax-based, compulsory private insurance, employer insurance, private insurance and uninsured systems with varying degrees of centralisation and devolution. Students will consider how health technology assessment (HTA) fits within these systems, looking at one or two countries as particular examples.

15 credits

Cost-effectiveness Modelling in International Health Technology Assessment DL

This unit sets out the different uses of modelling in Health Technology Assessment (HTA), together with the main principles and common techniques (including Markov models and individual level simulation). It reviews the international guidance on good practice and develops particpants' skills to appraise and commission models for HTA. Learning is based around a core international literature on modelling covering methodological papers and a substantial set of case studies, ensuring learning is grounded in real world examples. Participants also undertake some simple 'hands-on' model-building and model reviewing in EXCEL to help embed the principles learned.Students interested to learn more about building cost-effectiveness models can enrol the Building Cost-effectiveness Models for HTA module (HAR6119). This module runs in the Spring semester and is worth 15 credits.

15 credits

Economic Evaluation in International Health Technology Assessment DL

This unit introduces the concept of economic evaluation as applied to health technology assessment, the different types of evaluation that are available and the various stages and techniques that need to be applied to generate results. The techniques will be matched against current practice guidelines in different jurisdictions so that students can understand the current policy context of the methods. Also, as additional techniques are described, the strengths and weaknesses of each will be highlighted, with the students being encouraged to critically appraise their appropriateness to different contexts and jurisdictions.

15 credits

International Health Technology Assessment and Reimbursement Real World Case Studies

This module provides students with real-world case-studies of HTA submissions for a range of therapeutic interventions, and encourages a critical approach to the evaluation of the different methods used. The module is a summation of the taught modules for students on the diploma programme, introduces advanced topics and prepares Masters students for the long project module.

15 credits

Long Project

This is the long project for the MSc in International Health Technology Assessment, Pricing and Reimbursement. It is designed to allow students to integrate their knowledge of health technology assessment, pricing and reimbursement acquired throughout the MSc, using a real or hypothetical case study of a health technology to prepare a value case for submission in multiple jurisdictions.

60 credits

Optional modules - two from:

Randomised Controlled Trials to Support Reimbursement Decision Making DL

Randomised controlled trials (RCTs) are of use when evaluating the effectiveness of interventions, as part of health technology assessment and decision-making. This unit covers the appropriate use of trials, the range of available research designs, strategies to optimise recruitment, sample size, outcome measures, and the use of economic and qualitative methods alongside trials.

15 credits

Using Evidence in the Design and Development of Models

This unit sets out the process of developing decision-analytic models in health technology assessment (HTA), and explains how this process is informed by evidence. It explores conceptual modelling, including how to understand decision problems and how to apply this understanding to the specification and population of a relevant decision-analytic framework. Students are introduced to information retrieval methods and formal problem structuring processes as applied to HTA.

15 credits

Building Cost-effectiveness Models for Health Technology Assessment

An advanced course teaching the technical and practical skills required to build cost-effectiveness models for international health technology assessment. It builds on from the introductory unit, HAR6113 Cost-effectiveness modelling in international HTA, which covered the principles behind modelling. Content includes problem definition and structuring, building decision tree and Markov/state transition models in Excel, identifying appropriate data sources, implementing deterministic and probabilistic sensitivity analysis, and Value of Information analysis. It is an advanced course, aimed at students with a strong mathematical background who want to go on to build their own economic models.Students require a mathematical / statistical background and a sound understanding of the principles of modelling (prior completion of HAR6113 or evidence of previous training/knowledge). Good pre-existing Excel skills are essential. For students considering this Module as a standalone option who only require an understanding of the principles of economic modelling and good practice and who need the skills to be able to review other people¿s models, but do not need the technical skills to build their own models, the introductory module HAR6113: Cost-effectiveness Modelling in International HTA may be a more appropriate choice of module.

15 credits

Utility and Patient-reported Outcomes Data in Health Technology Assessment

The module explores the assessment and generation of patient reported outcomes for use in international health technology assessment, the quality adjusted life year (QALY) model and its weaknesses, and alternative methods of valuing benefits. The approaches used to generate outcomes and other utility data will be explored in relation to current practice guidelines of reimbursement and other agencies in different countries.

15 credits

Core modules:

Methods and Processes in International Health Technology Assessment

This module outlines the process of Health Technology Assessment and sets out the framework by which companies may develop Therapeutic Value Propositions (TVPs), i.e. positions in a disease management pathway where a new technology may add value in terms of effectiveness, safety or cost. The module covers identification and synthesis of evidence to construct disease management pathways, and how to pinpoint areas of unmet need. It also covers an introduction to the types of evidence needed to demonstrate clinical and cost-effectiveness, including clinical trial design as well as non-trial evidence.

15 credits

Systematic Reviews and Evidence Synthesis: Principles DL

The purpose of this unit is to enable students to understand the principles of systematic review. It covers the defining characteristics and application of systematic reviews; how to search for and select relevant evidence; how to quality assess primary research articles; the key issues that may generate bias; and the general principles governing evidence synthesis.

15 credits

International Healthcare Systems and Reimbursement DL

This module introduces students to the range of healthcare and reimbursement systems to be found throughout the world, considering tax-based, compulsory private insurance, employer insurance, private insurance and uninsured systems with varying degrees of centralisation and devolution. Students will consider how health technology assessment (HTA) fits within these systems, looking at one or two countries as particular examples.

15 credits

Cost-effectiveness Modelling in International Health Technology Assessment DL

This unit sets out the different uses of modelling in Health Technology Assessment (HTA), together with the main principles and common techniques (including Markov models and individual level simulation). It reviews the international guidance on good practice and develops particpants' skills to appraise and commission models for HTA. Learning is based around a core international literature on modelling covering methodological papers and a substantial set of case studies, ensuring learning is grounded in real world examples. Participants also undertake some simple 'hands-on' model-building and model reviewing in EXCEL to help embed the principles learned.Students interested to learn more about building cost-effectiveness models can enrol the Building Cost-effectiveness Models for HTA module (HAR6119). This module runs in the Spring semester and is worth 15 credits.

15 credits

Economic Evaluation in International Health Technology Assessment DL

This unit introduces the concept of economic evaluation as applied to health technology assessment, the different types of evaluation that are available and the various stages and techniques that need to be applied to generate results. The techniques will be matched against current practice guidelines in different jurisdictions so that students can understand the current policy context of the methods. Also, as additional techniques are described, the strengths and weaknesses of each will be highlighted, with the students being encouraged to critically appraise their appropriateness to different contexts and jurisdictions.

15 credits

International Health Technology Assessment and Reimbursement Real World Case Studies

This module provides students with real-world case-studies of HTA submissions for a range of therapeutic interventions, and encourages a critical approach to the evaluation of the different methods used. The module is a summation of the taught modules for students on the diploma programme, introduces advanced topics and prepares Masters students for the long project module.

15 credits

Optional modules - two from:

Randomised Controlled Trials to Support Reimbursement Decision Making DL

Randomised controlled trials (RCTs) are of use when evaluating the effectiveness of interventions, as part of health technology assessment and decision-making. This unit covers the appropriate use of trials, the range of available research designs, strategies to optimise recruitment, sample size, outcome measures, and the use of economic and qualitative methods alongside trials.

15 credits

Using Evidence in the Design and Development of Models

This unit sets out the process of developing decision-analytic models in health technology assessment (HTA), and explains how this process is informed by evidence. It explores conceptual modelling, including how to understand decision problems and how to apply this understanding to the specification and population of a relevant decision-analytic framework. Students are introduced to information retrieval methods and formal problem structuring processes as applied to HTA.

15 credits

Building Cost-effectiveness Models for Health Technology Assessment

An advanced course teaching the technical and practical skills required to build cost-effectiveness models for international health technology assessment. It builds on from the introductory unit, HAR6113 Cost-effectiveness modelling in international HTA, which covered the principles behind modelling. Content includes problem definition and structuring, building decision tree and Markov/state transition models in Excel, identifying appropriate data sources, implementing deterministic and probabilistic sensitivity analysis, and Value of Information analysis. It is an advanced course, aimed at students with a strong mathematical background who want to go on to build their own economic models.Students require a mathematical / statistical background and a sound understanding of the principles of modelling (prior completion of HAR6113 or evidence of previous training/knowledge). Good pre-existing Excel skills are essential. For students considering this Module as a standalone option who only require an understanding of the principles of economic modelling and good practice and who need the skills to be able to review other people¿s models, but do not need the technical skills to build their own models, the introductory module HAR6113: Cost-effectiveness Modelling in International HTA may be a more appropriate choice of module.

15 credits

Utility and Patient-reported Outcomes Data in Health Technology Assessment

The module explores the assessment and generation of patient reported outcomes for use in international health technology assessment, the quality adjusted life year (QALY) model and its weaknesses, and alternative methods of valuing benefits. The approaches used to generate outcomes and other utility data will be explored in relation to current practice guidelines of reimbursement and other agencies in different countries.

15 credits

Optional modules - four from:

Methods and Processes in International Health Technology Assessment

This module outlines the process of Health Technology Assessment and sets out the framework by which companies may develop Therapeutic Value Propositions (TVPs), i.e. positions in a disease management pathway where a new technology may add value in terms of effectiveness, safety or cost. The module covers identification and synthesis of evidence to construct disease management pathways, and how to pinpoint areas of unmet need. It also covers an introduction to the types of evidence needed to demonstrate clinical and cost-effectiveness, including clinical trial design as well as non-trial evidence.

15 credits

Systematic Reviews and Evidence Synthesis: Principles DL

The purpose of this unit is to enable students to understand the principles of systematic review. It covers the defining characteristics and application of systematic reviews; how to search for and select relevant evidence; how to quality assess primary research articles; the key issues that may generate bias; and the general principles governing evidence synthesis.

15 credits

International Healthcare Systems and Reimbursement DL

This module introduces students to the range of healthcare and reimbursement systems to be found throughout the world, considering tax-based, compulsory private insurance, employer insurance, private insurance and uninsured systems with varying degrees of centralisation and devolution. Students will consider how health technology assessment (HTA) fits within these systems, looking at one or two countries as particular examples.

15 credits

Cost-effectiveness Modelling in International Health Technology Assessment DL

This unit sets out the different uses of modelling in Health Technology Assessment (HTA), together with the main principles and common techniques (including Markov models and individual level simulation). It reviews the international guidance on good practice and develops particpants' skills to appraise and commission models for HTA. Learning is based around a core international literature on modelling covering methodological papers and a substantial set of case studies, ensuring learning is grounded in real world examples. Participants also undertake some simple 'hands-on' model-building and model reviewing in EXCEL to help embed the principles learned.Students interested to learn more about building cost-effectiveness models can enrol the Building Cost-effectiveness Models for HTA module (HAR6119). This module runs in the Spring semester and is worth 15 credits.

15 credits

Economic Evaluation in International Health Technology Assessment DL

This unit introduces the concept of economic evaluation as applied to health technology assessment, the different types of evaluation that are available and the various stages and techniques that need to be applied to generate results. The techniques will be matched against current practice guidelines in different jurisdictions so that students can understand the current policy context of the methods. Also, as additional techniques are described, the strengths and weaknesses of each will be highlighted, with the students being encouraged to critically appraise their appropriateness to different contexts and jurisdictions.

15 credits

International Health Technology Assessment and Reimbursement Real World Case Studies

This module provides students with real-world case-studies of HTA submissions for a range of therapeutic interventions, and encourages a critical approach to the evaluation of the different methods used. The module is a summation of the taught modules for students on the diploma programme, introduces advanced topics and prepares Masters students for the long project module.

15 credits

Randomised Controlled Trials to Support Reimbursement Decision Making DL

Randomised controlled trials (RCTs) are of use when evaluating the effectiveness of interventions, as part of health technology assessment and decision-making. This unit covers the appropriate use of trials, the range of available research designs, strategies to optimise recruitment, sample size, outcome measures, and the use of economic and qualitative methods alongside trials.

15 credits

Using Evidence in the Design and Development of Models

This unit sets out the process of developing decision-analytic models in health technology assessment (HTA), and explains how this process is informed by evidence. It explores conceptual modelling, including how to understand decision problems and how to apply this understanding to the specification and population of a relevant decision-analytic framework. Students are introduced to information retrieval methods and formal problem structuring processes as applied to HTA.

15 credits

Building Cost-effectiveness Models for Health Technology Assessment

An advanced course teaching the technical and practical skills required to build cost-effectiveness models for international health technology assessment. It builds on from the introductory unit, HAR6113 Cost-effectiveness modelling in international HTA, which covered the principles behind modelling. Content includes problem definition and structuring, building decision tree and Markov/state transition models in Excel, identifying appropriate data sources, implementing deterministic and probabilistic sensitivity analysis, and Value of Information analysis. It is an advanced course, aimed at students with a strong mathematical background who want to go on to build their own economic models.Students require a mathematical / statistical background and a sound understanding of the principles of modelling (prior completion of HAR6113 or evidence of previous training/knowledge). Good pre-existing Excel skills are essential. For students considering this Module as a standalone option who only require an understanding of the principles of economic modelling and good practice and who need the skills to be able to review other people¿s models, but do not need the technical skills to build their own models, the introductory module HAR6113: Cost-effectiveness Modelling in International HTA may be a more appropriate choice of module.

15 credits

Utility and Patient-reported Outcomes Data in Health Technology Assessment

The module explores the assessment and generation of patient reported outcomes for use in international health technology assessment, the quality adjusted life year (QALY) model and its weaknesses, and alternative methods of valuing benefits. The approaches used to generate outcomes and other utility data will be explored in relation to current practice guidelines of reimbursement and other agencies in different countries.

15 credits