Dr Myles Jones BSc, MSc, PhD, SFHEA
Department of Psychology
The University of Sheffield
Sheffield S10 2TP, UK
Tel: (+44) 0114 22 26551
Fax: (+44) 0114 27 66515
Research Group: Neurovascular and Neuroimaging Research Group
BSc Psychology (Sheffield), MSc Neuroscience (Institute of Psychiatry), PhD Psychology (Sheffield)
Non-invasive functional neuroimaging techniques
Non-invasive functional neuroimaging techniques such as blood oxygen level dependent (BOLD) functional magnetic imaging (fMRI) are frequently used to map the cognitive architecture of the human brain. Such techniques however, do not measure neural activity per se but rather rely on the accompanying changes in blood flow, volume and oxygenation (termed `the haemodynamic response´) to infer the loci and magnitude of neural activation.
Interpreting imaging data
Characterising cerebral hemodynamics and understanding their relationship with the underlying brain activity is essential for the correct interpretation of imaging data. I have used optical techniques to provide direct measures of the cortical hemodynamic response to sensory and visual stimuli.
Stimulus-evoked neural activity and hemodynamics
Additional multi-electrode recording techniques have allowed exploration of the relationship between stimulus-evoked neural activity and hemodynamics across a wide range of stimulus conditions. I have also explored how this relationship may alter during changes in brain state and baseline levels of blood flow.
“Resting-state” neuroimaging data
In addition to stimulus evoked changes, spontaneous fluctuations in neuroimaging signals also occur in the absence of stimuli or tasks. Although these fluctuations are widely used to infer ongoing activity and connectivity their relationship with underling spontaneous brain activity has not been fully elucidated. As such, I am currently characterising these signals and their relationship with the underlying activity. This has required development of time frequency analyses that can also be applied to EEG data.
BBSRC. Understanding neural excitation and inhibition: implications for the interpretation of extracellular field potentials and neurovascular coupling. Y. Zheng (PI), J.Berwick, S. Billings, D. Coca, M.Jones, A.Kennerley, E.Milne, P.Redgrave. £768,882; 8/2013-08/2016
Medical Research Council (MRC). The neurophysiological basis of prolonged negative BOLD signals. J.Berwick (PI), M.Jones, A.Kennerley, L.Boorman, C. Martin, P. Redgrave, Y. Zheng. £655,000; 06/2011-05/2014
EPSRC. Engineering virus-like nanoparticles for targeting the central nervous system. G Battaglia (PI), S P. Armes, M. Azzouz, O. Bandmann, J. Berwick, P.G. Ince , A.J. Kennerley, M. Jones, R. Golestanian, R. Hose, R. Mead, K. Ning, A.J. Ryan, P. Shaw, R. Smallwood, D. Walker & Y. Zheng. £ 2,060,808; 05/2009-04/2012
MRC, New Investigator Award (NIA) "Neurovascular coupling during information processing states." M.Jones (PI) £197,000; 09/2006-08/2009
Teaching and administrative duties
I am Director of Undergraduate Studies for Psychology and thus chair The Psychology Department Teaching Committee. I am also a member of The Psychology Department Ethics Committeee and The Undergraduate Staff-Student Committee. I am module organiser for Neuroscience (PSY 219) and teach on Introduction to Psychology (PSY101), Neuroscience and Evolutionary Psychology (PSY 108) and The Fundamentals of Neuroscience (PSY6306). I am also involved in the scholarship of teaching and am a Senior Fellow of the Higher Education Academy (SFHEA) and a University of Sheffield, Senate Award Fellow of Excellence in Learning and Teaching. I am also an assessor of University of Sheffield HEA fellowships.
Post-Doctoral Research Associates
Dr Michael Bruyns-Haylett (BBSRC, Co-I, 2013-2016)
Dr Luke Boorman (MRC, Co-I, 2011-2014)
Abdullah Bin Dawood (2015-2018, Principal Supervisor)
Dr Priya Patel (TUOS Demonstratorship, 2012-2016, Principal Supervisor)
Reem Abdal-Sahib (TUOS Demonstratorship, 2015-2019, Co-Supervisor)
Marco Mcsweeney (TUOS Faculty of Science Studentship, 2015-2018, Co-Supervisor)
Dr Rebecca Slack (TUOS Demonstratorship, 2012-2016, Co-Supervisor)
Dr Kira Shaw (A*Star, 2012-2016, Co-Supervisor)
Dr Abigail Dickinson (TUOS Studentship, 2012-2015, Co-Supervisor)
Dr Michael Bruyns-Haylett (TUOS Studentship, 2009-2012, Principal Supervisor)
Dr Kate Bartlett (TUOS Studentship, 2005-2008, Principal Supervisor)
Dr Luke Boorman (EPSRC, 2005-2008, Co-Supervisor)
Sheffield Undergraduate Research Scheme (SURE)
Benjamin F Goude (2016)
Zoe Reader (2014)
Elizabeth Kingsmill (2012)
Harry Kay Prize Winning Undergraduate Project Students
Emma Allde (2015)
Zoe Reader (2015)
Charlotte Bentham (2013)
Eleanor Haskins (2012)
Frances Byrne (2011)
Jamie Woolley (CCN, 2013-2014)
Michael Bruyns-Haylett (CCN, 2007-2008)
Janine Bijsterbosch (BICN, 2006-2007)
Activities and Distinctions
Editorial Board of
- Applied Optics
- Brain Connectivity
- Brain Topography
- Cerebral Cortex
- European Journal of Neuroscience
- European Neuropsychopharmacology
- French National Research Agency (ANR)
- Frontiers in Cognitive Science
- Frontiers in Neuroanatomy
- Frontiers in Neuroenergetics
- HEA Teaching Development Grants
- Human Brain Mapping Conference
- Journal of Applied Physiology
- Journal of Neurophysiology
- Journal of Neuroscience
- Journal of Neuroscience Methods
- Journal of Undergraduate Neuroscience Education (JUNE)
- Neurobiology of Ageing
- Transactions on Medical Imaging
- Wellcome Trust
Invited talks: Research
Department of Physiology and Pharmacology, Neuroscience Seminar Series, The University of Bristol, 27/02/12
Faculty of Life Sciences, Neuroscience Research Seminar Series, The University of Manchester, UK. 27/11/10
Department of Life Sciences, The Open University, UK. 10/11/09
32nd European Conference on Visual Perception. Regensburg, Germany. Symposium: Neurophysiological basis of BOLD signals. 27/08/09.
MRC Centre for Neurodegeneration Research, Institute of Psychiatry, Kings College. London. UK. 04/12/2007.
University of Manchester, Faculty of Life Sciences (PhD:2011;2013)
University of Birmingham, Department of Psychology (Mres: 2011-2015)
'Inquiry-based Learning across the Curriculum' - Departmental Award (£4,000). IBL Awards Scheme 2007/08
PEBBLE - Psychological Enquiry-Based Learning: M. Jones, R. Rowe, J. Andrade & J.May (Funded by CILASS, £12,000)
Teaching Seminar Series, Faculty of Arts & Humanities and Faculty of Social Sciences. University of Reading. 3/3/10. (Invited)
M. Jones and P. McKinney (2008)“Journals contain Facts unlike the Daily Mail”: implementation of an inquiry-based learning task enabling evaluation of information sources. Psychology Learning and Teaching (PLAT) HEA Conference Paper presentation, University of Bath, 02/7/08. (Invited)
M. Jones and P. McKinney (2008) “Journals contain facts unlike the daily mail”: implementation of an inquiry-based learning task enabling evaluation of information sources. LTEA Conference, Paper presentation, University of Sheffield, 6/06/08
PSY 101 - Discovering Psychology: Mind, Brain and Interaction
PSY 108 - Neuroscience and Evolutionary Psychology
PSY 219 - Neuroscience
PSY 6306 - Fundamentals of Neuroscience
A list of key publications can be found below. A full list of publications.
- Bruyns-Haylett M, Harris S, Boorman L, Zheng Y, Berwick J & Jones M (2013) The resting-state neurovascular coupling relationship: rapid changes in spontaneous neural activity in the somatosensory cortex are associated with haemodynamic fluctuations that resemble stimulus-evoked haemodynamics.. Eur J Neurosci, 38(6), 2902-2916.
- Bruyns-Haylett M, Zheng Y, Berwick J & Jones M (2010) Temporal coupling between stimulus-evoked neural activity and hemodynamic responses from individual cortical columns.. Phys Med Biol, 55(8), 2203-2219.
- Boorman L, Kennerley AJ, Johnston D, Jones M, Zheng Y, Redgrave P & Berwick J (2010) Negative blood oxygen level dependence in the rat: a model for investigating the role of suppression in neurovascular coupling.. J Neurosci, 30(12), 4285-4294.
- Saka M, Berwick J & Jones M (2010) Linear superposition of sensory-evoked and ongoing cortical hemodynamics.. Front Neuroenergetics, 2. View this article in WRRO
- Jones M, Devonshire IM, Berwick J, Martin C, Redgrave P & Mayhew J (2008) Altered neurovascular coupling during information-processing states.. Eur J Neurosci, 27(10), 2758-2772.
- Jones M, Berwick J, Johnston D & Mayhew J (2001) Concurrent optical imaging spectroscopy and laser-Doppler flowmetry: the relationship between blood flow, oxygenation, and volume in rodent barrel cortex.. Neuroimage, 13(6 Pt 1), 1002-1015.