Dr Gordon Cooper

School of Biosciences

Senior University Teacher, and Director of Learning and Teaching

Examinations Officer

Gordon Cooper
g.j.cooper@sheffield.ac.uk
+44 114 222 4667

Full contact details

Dr Gordon Cooper
School of Biosciences
B2 222a
Alfred Denny Building
Western Bank
Sheffield
S10 2TN
Profile
  • 2019 - Present: Senior University Teacher and Examination Officer, Department of Biomedical Science, University of Sheffield
  • 2014 - 2019: Senior Lecturer and Examination Officer, Department of Biomedical Science, University of Sheffield
  • 2002-2014: Lecturer, Department of Biomedical Science, University of Sheffield
  • 2000-02: Research Associate, Department of Biomedical Science, University of Sheffield
  • 1999-00: Research Associate - School of Biological Science, University of Manchester
  • 1996-99: Postdoctoral Fellow - Dept. Cellular & Molecular Physiology, Yale University, New Haven, Ct, USA
  • 1993-96: Research Associate - Dept. Physiology, University of Leeds
  • 1990-93: Ph.D. - University of Leeds
  • 1987-90: B.Sc. Physiology (Hons) - University of Leeds
Research interests
  • Transport of gases and urea by membrane proteins
  • Function of renal potassium channels

Epithelial Transport and the movement of small solutes across biological membranes

The underlying theme to my research has been the transport of small solutes and ions across biological membranes, in particular within the kidney and other epithelia. The regulated transport of small solutes such as urea and carbon dioxide plays a critical role in whole body homeostasis.

In classifying my current research I would split it into two major themes. Firstly is the transport of water and gases across biological membranes via Aquaporins. This theme incorporates collaborations with Walter Boron (Case Western) and Gordon Cramb (St Andrews). The second theme focuses on the handling of urea by the kidney, a process critical in the ability of the body to concentrate urine. This process of renal urea handling also has implications in the regulation of blood pressure.  This theme involves collaborations with Craig Smith (Manchester) and Gavin Stewart (Dublin).

Over the last few years I have been actively involved in the redevelopment of the delivery of Physiology practical classes within the University. As part of a Physiological Society funded project I have co-ordinated the production of an online teaching resource that has facilitated the delivery of undergraduate practical sessions.

Publications

Show: Featured publications All publications

Journal articles

All publications

Journal articles

Conference proceedings papers

  • Collins VM, Cooper GJ & White SJ (2006) Apical membrane targeting of ROMK2 is independent of N-linked glycosylation. FASEB JOURNAL, Vol. 20(4) (pp A328-A328) RIS download Bibtex download
  • White SJ, Cooper GJ, Hajihashemi S, Ware TL & Murray LA (2003) Cloning and functional expression of zebrafish (Danio rerio) ROMK2 (Kir1.1 b).. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 79A-79A) RIS download Bibtex download
  • Cooper GJ (2003) The functional unit of a frog urea transporter (fUT) is multimeric.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 75A-75A) RIS download Bibtex download
  • White SJ, Hajihasemi S, Cooper GJ, Robson L & Ortega B (2003) A C-terminal mutation enhances ROMK2 stability in oocytes and MDCK cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 78A-78A) RIS download Bibtex download
  • Collins VM, Cooper GJ & White SJ (2002) The N terminus of ROMK2 is necessary for channel function but not membrane trafficking. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 544 (pp 8P-8P) RIS download Bibtex download
  • Cooper G, Hurst A, Lynch P & Hunter M (1994) Pump-leak coupling in the amphibian diluting segment. Kidney and Blood Pressure Research, Vol. 17(3-4) (pp 138-142) RIS download Bibtex download
  • Cooper GJ & Hunter M (1993) Alteration of Na+-H+ exchanger setpoint by furosemide (frusemide) in frog isolated early distal tubule (EDT). Journal of Physiology, Vol. 467 RIS download Bibtex download
  • Cooper G, Stone V & Hunter M (1992) Furosemide induces cytoplasmic alkalinization in frog early distal tubules. Journal of Physiology, Vol. 446 RIS download Bibtex download
Grants
  • The Physiological Society - David Jordan Teaching Grant
  • NERC
  • Kidney Research UK.
Teaching activities

Undergraduate and postgraduate taught modules

Undergraduate:

  • BMS109-108 Physiology with Pharmacology
  • BMS109 Lab Skills & Skills Sessions
  • BMS109 Introduction to Organ Systems
  • BMS221 Physiology at the Extreme
  • BMS242/43 Career Development Skills (Coordinator)
  • BMS242/243 Core Phys Pharm
  • BMS242, 244 CVS Respiratory
  • BMS311 The Kidney in Health & Disease
  • BMS346 Epithelial Physiology in Health and Disease
  • BMS316 Group Research Initiatives (Coordinator)
  • Level 3 Practical and Dissertation Modules

Masters (MSc):

  • BMS6063 Epithelial Physiology in Health and Disease
Professional activities
  • Fellow of the Physiological Society
  • Senior Fellow of the Higher Education Academy (SFHEA)
  • Invited Speaking. September 2013 - Invited speaker at Symposium on Mammalian Urea Transporters held at University College in Dublin.