Dr Louise Robson

Department of Biomedical Science

Senior University Teacher and Chair of Exam Board

Dr Louise Robson
l.robson@sheffield.ac.uk
+44 114 222 4688

Full contact details

Dr Louise Robson
Department of Biomedical Science
Firth Court
Western Bank
Sheffield
S10 2TN
Profile
  • 2019 - Present: Senior University Teacher and Director of Learning and Teaching, Department of Biomedical Science, The University of Sheffield
  • 2016 - 2019: Senior Lecturer & Director of Learning and Teaching, Department of Biomedical Science, The University of Sheffield
  • 2005 - 2016: Senior Lecturer (and Chief UCAS Selector), Department of Biomedical Science, University of Sheffield
  • 1996 - 2005 Lecturer: Department of Biomedical Science, University of Sheffield
  • 1992 - 1996: Postdoctoral research associate, Department of Physiology, University of Leeds
  • 1989 - 1992: PhD, Department of Physiology, University of Leeds
Research interests

Our research is focused on the role of ion channels in the physiology and pathophysiology of epithelial cells, particularly intestinal and airway cells. In collaboration with R Muimo (Medical School) we have a particular interest in cystic fibrosis and the role of CFTR in airway and the intestine.  Previous work in the kidney has concentrated on the role of K+ channels and the K+ channel regulator KCNE1.

Epithelial physiology

My research is focused on the role of ion channels in the physiology and pathophysiology of epithelial cells, particularly airway cells, but also renal and gut. Previous work has investigated the role of K+ channels and the K+ channel regulator KCNE1 in renal cells, and also TRP channels in airway and bone.

Current research is focussed on investigating the role of the Cl- channel CFTR in airway Cl- secretion. CFTR is the channel mutated in the disease cystic fibrosis. The lab works with R Muimo (Medical School) and A Mehta (University of Dundee) to investigate proteins that interact with the CFTR protein.

We work with C Taylor (Sheffield Children’s Hospital) investigating compounds that may have therapeutic potential in cystic fibrosis, and also carry out diagnostic work on individuals who have an inconclusive sweat test (the standard test for diagnosis of cystic fibrosis).

Publications

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Journal articles

All publications

Journal articles

Conference proceedings papers

  • England AK, Muimo R & Robson L (2011) A potential role of tyrosine phosphorylation in the function of the cystic fibrosis transmembrane conductance regulator (CFTR). FASEB JOURNAL, Vol. 25 RIS download Bibtex download
  • Robson L, Neal A, Taylor H, Millar I, White S & Kibble J (2011) KCNE1 regulates a chromanol-sensitive pathway in mouse kidney. FASEB JOURNAL, Vol. 25 RIS download Bibtex download
  • Robson L, Neal AM & Kibble JD (2005) Clorilium mimics the renal response of KCNE1 knockout mice. FASEB JOURNAL, Vol. 19(5) (pp A1173-A1173) RIS download Bibtex download
  • Lee AT, Ong ACM & Robson L (2005) Localisation of polycystin-1 and 2 in a mouse collecting duct cell line. FASEB JOURNAL, Vol. 19(4) (pp A148-A148) RIS download Bibtex download
  • Robson L, Laycock SK, Brier T, Ong ACM & Haigh C (2003) A Ca2+-activated conductance in cultured mouse collecting duct cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 80A-80A) RIS download Bibtex download
  • Davies JP & Robson L (2003) Antagonist sensitivity of a P2X receptor in frog isolated proximal tubule cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 83A-83A) RIS download Bibtex download
  • White SJ, Hajihasemi S, Cooper GJ, Robson L & Ortega B (2003) A C-terminal mutation enhances ROMK2 stability in oocytes and MDCK cells.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, Vol. 14 (pp 78A-78A) RIS download Bibtex download
  • Davies JP & Robson L (2002) Role of P2X receptors in volume regulation in renal proximal tubule cells isolated from frog. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 544 (pp 98P-98P) RIS download Bibtex download
  • Khandel K & Robson L (2001) Quinidine inhibits Na+-alanine cotransport currents in frog isolated renal proximal tubule cells. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 535 (pp 24P-25P) RIS download Bibtex download
  • Millar ID, White SJ, Kibble JD & Robson L (2001) IsK does not regulate a basolateral channel in mouse renal proximal convoluted tubules. JOURNAL OF PHYSIOLOGY-LONDON, Vol. 535 (pp 24P-24P) RIS download Bibtex download
  • Robson L & Hunter M (1993) Slowing of K+ current rundown by ATP is independent of ATP hydrolysis in proximal tubule cells isolated from frog kidney. Journal of Physiology, Vol. 467 RIS download Bibtex download
  • Robson L & Hunter M (1993) Gadolinium inhibits a voltage-independent current in cells isolated from frog proximal tubule. Journal of Physiology, Vol. 467 RIS download Bibtex download
  • Robson L & Hunter M (1992) What is the cause of the repolarization observed after addition of alanine to the bathing solution of cells isolated from frog proximal tubule?. Journal of Physiology, Vol. 446 RIS download Bibtex download
  • Robson L & Hunter M (1990) Increases of frog isolated proximal tubule cell lenghts induced by hypotonic shock and alanine. Journal of Physiology, Vol. 430 RIS download Bibtex download
Teaching interests

I have been at Sheffield since 1996, and teach at all levels across the courses in Biomedical Science.  One of the things I have always tried to do is use new and innovative ways to deliver sessions to students, principally to strengthen their understanding of physiology but also to develop their transferable skills.

I use a mixture of traditional approaches such as lectures and project work, together with and alternative approaches such as online quizzes, problem solving sessions and lecture capture to deliver modules and sessions. 

I am always looking to embed digital technologies to not only teach but provide academic and pastoral support to students as well.  I am also very active in outreach work, delivering sessions in Science Week every year and talking at the Royal Institution in London.  As an enthusiastic teacher I aim to really grab student attention, ensuring I equip them with the knowledge and skills needed to succeed after they graduate.

Teaching activities

Undergraduate:

  • BMS109-108 Physiology with Pharmacology
  • BMS242/245 Phys Pharm Cells (Coordinator)
  • BMS242/243 Core Phys Pharm
  • BMS303 Molecular Physiology of Ion Channels  (Coordinator)
  • BMS311 The Kidney in Health & Disease (Coordinator)
  • BMS346 Epithelial Physiology in Health & Disease (Coordinator)
  • BMS6063 Epithelial Physiology in health and diseas

Masters (MSc):

  • BMS6062 Molecular Physiology of Ion Channels and Human Disease (Coordinator)
  • BMS6063 Epithelial Physiology in Health and Disease (Coordinator)

Other:

  • BMS603 Science in Schools
Professional activities
  • Physiological Society Otto Hutter Teaching prize winner (2018)
  • Senior Fellow of the Physiological Society (2017 onwards)
  • Senior Fellow of the Higher Education Academy (SFHEA) (2016 onwards)
  • Senate Award for Sustained Excellence in Learning and Teaching (2009)
  • Member of the Meetings Committee of the Physiological Society (2015-2018)
  • Chair of the Physiological Society Education Committee (2008-2012)
  • Reviewing editor for the Journal of Physiology (2012-2015)
  • Member of the Executive Committee of the Physiological Society (2008-2012)
  • Physiological Society Biller Prize (2002)
  • Active in Outreach and Access work in schools
  • Lecturer for the Royal Institution
  • Winner of 'Best overall lecturer in BMS' (2015 to 2019)
  • Fellow of the Royal Society of Biology (2020 onwards)
  • Committee member of the Royal Society of Biology Yorkshire Branch (2020 onwards)