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Research in the Department of Biomedical Science is focused on understanding mechanisms underpinning the development and functioning of cells, organs and whole organisms in both health and disease. Our interactions with clinical colleagues at the Sheffield hospitals are highly productive and ensure that the fundamental science being undertaken within the department is effectively disseminated into the medical arena. Our four research themes reflect the areas in which we have particular strengths and interests.

Research Themes


Cell Biology and Cancer research is focused on understanding fundamental cellular mechanisms with a particular emphasis on regulation of membrane traffic and cytoskeletal dynamics.

Cell Biology and Cancer


Development and Disease deals with the fascinating question of how a complex organism is generated from a single cell.

Development and Disease


Neuroscience in our department extends from development of the nervous system and neuronal cell biology, through to sensory neurophysiology and computational modelling.



Stem cells are cells that can divide indefinitely while retaining not only their own characteristics, but also the ability to differentiate into other cell types.

Stem Cell and Regenerative Medicine

Outstanding research

The quality of our research is outstanding as demonstrated by our publication output, the international standing of many of our researchers and our sustained position in research assessment exercises ranking as the 1st for Medical Research Excellence and 5th for Biological Sciences in the REF2014, and Joint 3rd for Biological Sciences, RAE2008.

We are also proud to host a number of prestigious independent research fellows and have a strong reputation for ensuring strong mentoring and support for researchers at all levels.

Our research is supported by outstanding facilities all of which are housed within the department. These include the light and electron microscope facilities; biological mass spectrometry; extensive zebrafish aquaria, a Drosophila facility, and RNAi screening.

Facilities and services

PhD opportunities

We welcome applicants for PhD research in any of our highlighted theme areas. Please review the web page for the theme that you're interested in for more details on the projects on offer, or explore our PhD opportunities page.

PhD opportunities

Independent Research Fellowships

Our programme for Independent Research Fellows is designed to establish you as a research leader in an ambitious, vibrant and supportive environment.

Long-term Fellows in the Faculty of Science at the University of Sheffield get:

  • the offer of an academic position after their Fellowship
  • a PhD student to kick-start their research portfolio

Learn more and apply