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Research

Research in the Department of Biomedical Science is focused on understanding mechanisms underpinning the development and functioning of cells, organs and whole organisms in both health and disease. Our interactions with clinical colleagues at the Sheffield hospitals are highly productive and ensure that the fundamental science being undertaken within the department is effectively disseminated into the medical arena. Our four research themes reflect the areas in which we have particular strengths and interests.

Research Themes

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Cell Biology and Cancer research is focused on understanding fundamental cellular mechanisms with a particular emphasis on regulation of membrane traffic and cytoskeletal dynamics.

These processes are essential, not only for the behaviour of individual cells, but also for how cells act in particular contexts and our studies therefore impact on other research themes within Biomedical Science.

Cell Biology and Cancer

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Development and Disease deals with the fascinating question of how a complex organism is generated from a single cell.

These studies give insights into what can go wrong during early development, how organs in our bodies adapt and change throughout life, and ultimately how we age.























Development and Disease

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Neuroscience in our department extends from development of the nervous system and neuronal cell biology, through to sensory neurophysiology and computational modelling.

Throughout this theme, we have internationally recognised strengths in sensory neuroscience of visual, auditory, and olfactory systems.




















Neuroscience

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Stem cells are cells that can divide indefinitely while retaining not only their own characteristics, but also the ability to differentiate into other cell types.

Throughout this theme, we are working to understand the mechanisms that control the proliferation and differentiation of human pluripotent stem cells so that they can be used safely in healthcare.

Stem Cell and Regenerative Medicine

Outstanding research

The quality of our research is outstanding as demonstrated by our publication output, the international standing of many of our researchers and our sustained position in research assessment exercises ranking as the 1st for Medical Research Excellence and 5th for Biological Sciences in the REF2014, and Joint 3rd for Biological Sciences, RAE2008.

We are also proud to host a number of prestigious independent research fellows and have a strong reputation for ensuring strong mentoring and support for researchers at all levels.

Our research is supported by outstanding facilities all of which are housed within the department. These include the light and electron microscope facilities; biological mass spectrometry; extensive zebrafish aquaria, a Drosophila facility, and RNAi screening.

Facilities and services

PhD project opportunities

We welcome applicants for PhD research in any of our highlighted theme areas. Please review the web page for the theme that you're interested in for more details on the projects on offer, or explore our PhD opportunities page.














PhD opportunities

Independent Fellowships in biology

We are seeking outstanding candidates wishing to launch their independent research careers by successful applications for Independent Research Fellowships (IRFs).














Fellowships