Dr Emily Noël

All publications

Journal articles

• Derrick CJ, Pollitt EJG, Sevilla Uruchurtu AS, Hussein F, Grierson AJ & Noël ES (2021) Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development.
• Bowley G, Kugler E, Wilkinson R, Lawrie A, Eeden F, Chico TJA, Evans PC, Noël ES & Serbanovic‐Canic J (2021) Zebrafish as a tractable model of human cardiovascular disease. British Journal of Pharmacology. View this article in WRRO
• Derrick CJ & Noël ES (2021) The ECM as a driver of heart development and repair. Development, 148(5), dev191320-dev191320.
• Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J & Noël ES (2021) Asymmetric Hapln1a drives regionalized cardiac ECM expansion and promotes heart morphogenesis in zebrafish development. Cardiovascular Research.
• Campbell K, Noël ES, Fletcher AG & Bulgakova NA (2020) Contemporary morphogenesis. Philosophical Transactions of the Royal Society B: Biological Sciences, 375(1809).
• Noël ES & Bakkers J (2017) Twists and turns: Computational modelling of the heart tube during development reveals the interplay between tissue asymmetry and growth that helps our hearts take shape. eLife, 6. View this article in WRRO
• Han MK, Hoijman E, Nöel E, Garric L, Bakkers J & de Rooij J (2016) αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish.. Biol Open, 5, 1461-1472. View this article in WRRO
• Noël ES, Momenah TS, Al-Dagriri K, Al-Suwaid A, Al-Shahrani S, Jiang H, Willekers S, Oostveen YY, Chocron S, Postma AV , Bhuiyan ZA et al (2016) A Zebrafish Loss-of-Function Model for Human CFAP53 Mutations Reveals Its Specific Role in Laterality Organ Function. Human Mutation, 37(2), 194-200.
• Wu C-C, Kruse F, Vasudevarao MD, Junker JP, Zebrowski DC, Fischer K, Noël ES, Grün D, Berezikov E, Engel FB , van Oudenaarden A et al (2016) Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell, 36(1), 36-49.
• Tessadori F, Noël ES, Rens EG, Magliozzi R, Evers-van Gogh IJA, Guardavaccaro D, Merks RMH & Bakkers J (2015) Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation. Developmental Cell, 32(5), 631-639.
• Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J & van Oudenaarden A (2014) Genome-wide RNA Tomography in the Zebrafish Embryo. Cell, 159(3), 662-675.
• Bonetti M, Paardekooper Overman J, Tessadori F, Noël E, Bakkers J & den Hertog J (2014) Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish. Development, 141(9), 1961-1970.
• Noël ES, Verhoeven M, Lagendijk AK, Tessadori F, Smith K, Choorapoikayil S, den Hertog J & Bakkers J (2013) A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nature Communications, 4(1).
• Smith KA, Noël E, Thurlings I, Rehmann H, Chocron S & Bakkers J (2011) Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish. PLoS Genetics, 7(9). View this article in WRRO
• Mas JC, Noël ES & Ober EA (2011) Chromatin Modification in Zebrafish Development, 401-428.
• Noël ES, Reis MD, Arain Z & Ober EA (2010) Analysis of the Albumin/α-Fetoprotein/Afamin/Group specific component gene family in the context of zebrafish liver differentiation. Gene Expression Patterns, 10(6), 237-243.
• Noël ES, Casal-Sueiro A, Busch-Nentwich E, Verkade H, Dong PDS, Stemple DL & Ober EA (2008) Organ-specific requirements for Hdac1 in liver and pancreas formation. Developmental Biology, 322(2), 237-250.

Chapters

• Noël ES (2024) Cardiac construction—Recent advances in morphological and transcriptional modeling of early heart development, Current Topics in Developmental Biology Elsevier

Conference proceedings papers

• Sanchez-Posada J & Noel ES (2022) morphoHeart: A novel tool to capture, quantify and link 3D asymmetric heart morphogenesis with spatiotemporal extracellular matrix dynamics in zebrafish cardiac development. JOURNAL OF ANATOMY, Vol. 240(4) (pp 785-786)
• Derrick CJ, Hussein F, Pollitt EJG & Noel ES (2021) Laminins regulate cardiac growth through restricting second heart field addition. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Vol. 102(2) (pp 126-126)
• Carr PL, Jiang Z, Savage AM, Noël ES, Wilkinson RN & Lawrie A (2019) Validating the Zebrafish Aortic Arch Development as a Model to Study the Molecular Mechanisms Underlying Idiopathic Pulmonary Arterial Hypertension. C49. TICKET TO RIDE: EXPERIMENTAL MODELS OF PAH

Preprints

• Sánchez-Posada J & Noël ES (2024) morphoHeart: a novel quantitative tool to perform integrated 3D morphometric analyses of heart and ECM morphology during embryonic development, Cold Spring Harbor Laboratory.
• Pollitt EJG, Derrick CJ, Sánchez-Posada J & Noël ES (2023) Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle, Cold Spring Harbor Laboratory.
• Derrick CJ, Pollitt EJG, Uruchurtu ASS, Hussein F & Noёl ES () Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development.
• Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J & Noël ES () Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development, Cold Spring Harbor Laboratory.