Publications
List of recent publications and articles from members of the CMIAD group.
Journal articles
- Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria. Current Biology. RIS | bibtex
- Proteasome-dependent protein quality control of the peroxisomal membrane protein Pxa1p. Biochimica et Biophysica Acta (BBA) - Biomembranes. RIS | bibtex
- The architecture of the Gram-positive bacterial cell wall. Nature. View this article in WRRO RIS | bibtex
- How does methotrexate work?. Biochemical Society Transactions, 48(2), 559-567. RIS | bibtex
- Interstitial lung disease in primary immunodeficiency: towards a brighter future. European Respiratory Journal, 55(4), 2000089-2000089. RIS | bibtex
- Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal. PLOS Biology, 18(3). View this article in WRRO RIS | bibtex
- Semaphorin 3F signaling actively retains neutrophils at sites of inflammation. Journal of Clinical Investigation. RIS | bibtex
- Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons. Toxicon: X, 5. View this article in WRRO RIS | bibtex
- Generation of otic lineages from integration-free human-induced pluripotent stem cells reprogrammed by mRNAs. Stem Cells International, 2020. View this article in WRRO RIS | bibtex
- A platform for context-specific genetic engineering of recombinant protein production by CHO cells. Journal of Biotechnology, 312, 11-22. RIS | bibtex
- Cross-talk between the tumor microenvironment, extracellular matrix, and cell metabolism in cancer. Frontiers in Oncology, 10. View this article in WRRO RIS | bibtex
- Porphyromonas gingivalis lipopolysaccharide rapidly activates trigeminal sensory neurons and may contribute to pulpal pain. International Endodontic Journal. View this article in WRRO RIS | bibtex
- Scratching the surface : bacterial cell envelopes at the nanoscale. mBio, 11(1). View this article in WRRO RIS | bibtex
- K+ accumulation and clearance in the calyx synaptic cleft of type I mouse vestibular hair cells. Neuroscience, 426, 69-86. View this article in WRRO RIS | bibtex
- Water loss regulates cell and vesicle volume. Science, 367(6475), 246-247. RIS | bibtex
- Prekallikrein – an emerging therapeutic target for Klebsiella pneumoniae infection? †. The Journal of Pathology, 250(4), 359-361. RIS | bibtex
- How the central domain of dystrophin acts to bridge F-actin to sarcolemmal lipids. Journal of Structural Biology, 209(1). View this article in WRRO RIS | bibtex
- Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea. The Journal of Physiology, 598(1), 151-170. View this article in WRRO RIS | bibtex
- The endocytic pathways of Dictyostelium discoideum. The International Journal of Developmental Biology, 63(8-9-10), 461-471. View this article in WRRO RIS | bibtex
- Multiple sclerosis drug FTY-720 toxicity is mediated by the heterotypic fusion of organelles in neuroendocrine cells. Scientific Reports, 9(1). View this article in WRRO RIS | bibtex
- The binding affinity of PTPN13’s tandem PDZ2/3 domain is allosterically modulated. BMC Molecular and Cell Biology, 20(1). View this article in WRRO RIS | bibtex
- Apoptotic signalling targets the post-endocytic sorting machinery of the death receptor Fas/CD95. Nature Communications, 10(1). View this article in WRRO RIS | bibtex
- Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection. Nature Communications, 10(1). View this article in WRRO RIS | bibtex
- Development of a gut-on-a-chip model for high throughput disease modeling and drug discovery. International Journal of Molecular Sciences, 20(22). View this article in WRRO RIS | bibtex
- The impact of hypoxia on the host-pathogen interaction between neutrophils and staphylococcus aureus. International Journal of Molecular Sciences, 20(22). View this article in WRRO RIS | bibtex
- JAK inhibition by methotrexate (and csDMARDs) may explain clinical efficacy as monotherapy and combination therapy. Journal of Leukocyte Biology, 106(5), 1063-1068. View this article in WRRO RIS | bibtex
- 2601. Identification of Staphylococcus aureus Genetic Factors Associatiated with the Subversion of Macrophage Phagosomal Acidification. Open Forum Infectious Diseases, 6(Supplement_2), S904-S904. RIS | bibtex
- Cell‐type specific visualization and biochemical isolation of endogenous synaptic proteins in mice. European Journal of Neuroscience. View this article in WRRO RIS | bibtex
- Low‐dose methotrexate: potential clinical impact on haematological and constitutional symptoms in myeloproliferative neoplasms. British Journal of Haematology, 187(3). RIS | bibtex
- Bone marrow osteoprogenitors are depleted whereas osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid. The FASEB Journal, 33(11), 12768-12779. View this article in WRRO RIS | bibtex
- The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis. Journal of Biological Chemistry, 294(42), 15418-15434. RIS | bibtex
- Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex. Current Biology, 29(19), 3323-3330.e8. RIS | bibtex
- Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function. EMBO Molecular Medicine, 11(9). View this article in WRRO RIS | bibtex
- Airway epithelial cells generate pro-inflammatory Tenascin-C and small extracellular vesicles in response to TLR3 stimuli and rhinovirus infection. Frontiers in Immunology, 10. View this article in WRRO RIS | bibtex
- S‐acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion. EMBO reports. View this article in WRRO RIS | bibtex
- Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing. Development, 146(15), dev174789-dev174789. RIS | bibtex
- Methodological standards, quality of reporting, and regulatory compliance in animal research on amyotrophic lateral sclerosis: a systematic review. BMJ Open Science, 3(1). View this article in WRRO RIS | bibtex
- Pellino-1 regulates immune responses to Haemophilus influenzae in models of inflammatory lung disease. Frontiers in Immunology, 10. View this article in WRRO RIS | bibtex
- Ca2+-activated K+ channels reduce network excitability, improving adaptability and energetics for transmitting and perceiving sensory information. Journal of Neuroscience. View this article in WRRO RIS | bibtex
- Membrane dynamics in cell migration. Essays In Biochemistry. View this article in WRRO RIS | bibtex
- Experimental and theoretical evidence for bidirectional signaling via core planar polarity protein complexes in Drosophila. iScience, 17, 49-66. View this article in WRRO RIS | bibtex
- The UK cellular microbiology network: Exploring the host‐bacterial interface. Cellular Microbiology, 21(9). RIS | bibtex
- Proteomic profiling, transcription factor modeling, and genomics of evolved tolerant strains elucidate mechanisms of vanillin toxicity in Escherichia coli.. mSystems, 4(4). View this article in WRRO RIS | bibtex
- Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses. Journal of Experimental Medicine, 216(9), 1986-1998. RIS | bibtex
- Secretion of mast cell inflammatory mediators is enhanced by CADM1-dependent adhesion to sensory neurons. Frontiers in Cellular Neuroscience, 13. View this article in WRRO RIS | bibtex
- Modularity, criticality, and evolvability of a developmental gene regulatory network. eLife, 8. View this article in WRRO RIS | bibtex
- A theoretical analysis of how plant growth is limited by carbon allocation strategies and respiration. in silico Plants (isP), 1(1). View this article in WRRO RIS | bibtex
- In Vitro Membrane Remodeling by ESCRT is Regulated by Negative Feedback from Membrane Tension. iScience, 15, 173-184. View this article in WRRO RIS | bibtex
- Reciprocal action of casein kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation. eLife, 2019(8). View this article in WRRO RIS | bibtex
- Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea. The Journal of Physiology. View this article in WRRO RIS | bibtex
- Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells. The EMBO Journal, 38(9), e99839-e99839. RIS | bibtex
- Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression. PLoS Genetics, 15(4). View this article in WRRO RIS | bibtex
- ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage. Oncogenesis, 8(5). View this article in WRRO RIS | bibtex
- Neutrophil GM-CSF receptor dynamics in acute lung injury.. Journal of Leukocyte Biology. View this article in WRRO RIS | bibtex
- Correction to: Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. Journal of Clinical Immunology, 39(2), 225-227. RIS | bibtex
- AP-2-Dependent Endocytic Recycling of the Chitin Synthase Chs3 Regulates Polarized Growth in Candida albicans.. mBio, 10(2). View this article in WRRO RIS | bibtex
- Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis. Brain, 142(3), 586-605. View this article in WRRO RIS | bibtex
- The intracellular domain of β-dystroglycan mediates the nucleolar stress response by suppressing UBF transcriptional activity. Cell Death and Disease, 10. View this article in WRRO RIS | bibtex
- Gamma secretase orthologs are required for lysosomal activity and autophagic degradation in Dictyostelium discoideum, independent of PSEN (presenilin) proteolytic function. Autophagy, 15(8), 1407-1418. RIS | bibtex
- PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection. PLoS Pathogens, 15(2). View this article in WRRO RIS | bibtex
- Emerging Regulatory Roles of Dual-Specificity Phosphatases in Inflammatory Airway Disease. International Journal of Molecular Sciences, 20(3). View this article in WRRO RIS | bibtex
- The breadth of macropinocytosis research. Philosophical Transactions of the Royal Society B: Biological Sciences, 374(1765), 20180146-20180146. RIS | bibtex
- Retromer Controls Planar Polarity Protein Levels and Asymmetric Localization at Intercellular Junctions. Current Biology, 29(.), 484-491.e6. View this article in WRRO RIS | bibtex
- The origins and evolution of macropinocytosis. Philosophical Transactions B: Biological Sciences, 374(1765). View this article in WRRO RIS | bibtex
- A theoretical framework for planar polarity establishment through interpretation of graded cues by molecular bridges. Development, 146(3). View this article in WRRO RIS | bibtex
- Yeast model based study identified myosin and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis. Disease Models & Mechanisms, 12(1). View this article in WRRO RIS | bibtex
- Cellular Microbiology Interview - Dr. Jason King.. Cellular Microbiology. View this article in WRRO RIS | bibtex
- Hair Cell Afferent Synapses: Function and Dysfunction. Cold Spring Harbor Perspectives in Medicine, 9(12), a033175-a033175. RIS | bibtex
- DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus Through IL-1β Signalling. Journal of Virology. View this article in WRRO RIS | bibtex
- The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host. International Journal of Molecular Sciences, 21(4), 1183-1183. RIS | bibtex
- Correction: Analysis of long dsRNA produced in vitro and in vivo using atomic force microscopy in conjunction with ion-pair reverse-phase HPLC. The Analyst, 144(22), 6773-6773. RIS | bibtex
- Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria. RIS | bibtex
- Dynamic coupling of cochlear inner hair cell intrinsic Ca2+action potentials to Ca2+signaling of non-sensory cells. RIS | bibtex
- Macrophages utilize mitochondrial fission to enhance mROS production during responses to Streptococcus pneumoniae. RIS | bibtex
- Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review. Clinical Reviews in Allergy & Immunology. RIS | bibtex
- Neutrophils use selective autophagy receptor p62/SQSTM1 to target Staphylococcus aureus for degradation in vivo in zebrafish. RIS | bibtex
Chapters
- Quantitative Analysis of Protein S-Acylation Site Dynamics Using Site-Specific Acyl-Biotin Exchange (ssABE). In Evans C, Wright P & Noirel J (Ed.), Mass Spectrometry of Proteins (pp. 71-82). New York: Humana Press. View this article in WRRO RIS | bibtex
Conference proceedings papers
- Long term actions of a recombinant advanced Botulinum toxin (BiTox-AA) molecule in migraine animal models. CEPHALALGIA, Vol. 39 (pp 230-230) RIS | bibtex
- Neutrophils activated with Hif-1 alpha are protective in zebrafish tuberculosis in vivo models. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, Vol. 49 (pp 67-68) RIS | bibtex
- Endogenous Circulating BMP9 Maintains Endothelial Cell Barrier Function. CARDIOVASCULAR DRUGS AND THERAPY, Vol. 33(2) (pp 269-270) RIS | bibtex